7 research outputs found
Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine:A potential role for homoserine kinase in insect-stage Trypanosoma brucei
10.1111/mmi.12853Molecular Microbiology951143-15
Rising to the occasion - Institutional standardization and organization of equipment for 'can't intubate, can't oxygenate' (CICO) crisis
'Can't intubate, can't oxygenate' (CICO) scenario is a rare anesthesia crisis for which the management has been suboptimal in the past. Inadequacy and disorganization of airway equipment have been identified as one of the latent factors that contribute to the failure of CICO management. We initiated a quality improvement project to review the equipment aspect of CICO management in our department. We revised our emergency front of neck access (FONA) airway equipment based on available evidence and organized the equipment with custom-made CICO kits. The CICO kits could potentially streamline management, and institutionally standardized equipment across all critical care departments. Our approach may serve as a practical guide for implementation of standard practice for CICO management
Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore
10.1186/s12884-017-1537-8BMC Pregnancy and Childbirth171Article number 364BPCMBGUSTO (Growing up towards Healthy Outcomes
International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module
•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's.
Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific.
Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days.
Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs.
Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically