3 research outputs found
Characterization and outcomes of 414 patients with primary SS who developed haematological malignancies
- Author
- Acar-Denizli N.
- Alberto Rojas R.
- Andrea Consani S.
- Argibay Filgueira A. B.
- Arma?an B.
- Armagan B.
- Astorri E.
- Atzeni F.
- Baldini C.
- Bartoloni E.
- Bombardieri M.
- Bombardieri S.
- Bootsma H.
- Brito-Zer('o)n P.
- Brun J. G.
- Carreira P.
- Carsons S. E.
- Comotto A.
- Danda D.
- De Miguel Campo B.
- De Vita S.
- Devauchelle-Pensec V.
- Dong X.
- Downie-Doyle S.
- Ericka D('i)az Cuiza P.
- Farris D. A.
- Febrer Nafria A. M.
- Fernandes Mo?a Trevisani V.
- Flores-Ch('a)vez A.
- Fonseca Aizpuru E.
- Fraile G.
- Gandolfo S.
- Gerli R.
- Gheita T. A.
- Giacomelli R.
- Giardina F.
- Gottenberg J. E.
- Hammenfors D.
- Hern('a)ndez-Molina G.
- Hernandez-Molina G.
- Herrera B. E.
- Hinrichs A.
- Hinrichs A. C.
- Hofauer B.
- Horvath I. F.
- Isenberg D.
- Izzo R.
- Kalyoncu U.
- Kawano M.
- Kilic L.
- Knopf A.
- Kostov B.
- Kruize A. A.
- Kvarnstrom M.
- Kwok S. -K.
- L('o)pez Dupla M.
- Li X.
- Mandl T.
- Mariette X.
- Maure Noia B.
- Melchor D('i)az S.
- Morcillo C.
- Morel J.
- Nakamura H.
- Nakamura T.
- Ng F.
- Nishihata S. -Y.
- Nordmark G.
- Olsson P.
- Park S. -H.
- Pasoto S. G.
- Praprotnik S.
- Priori R.
- Quartuccio L.
- Ramos-Casals M.
- Rasmussen A.
- Retamozo S.
- Rischmueller M.
- S('a)nchez Bern('a) I.
- S('a)nchez-Guerrero J.
- S(`e)ne D.
- Sandhya P.
- Santos Seoane S.
- Saraux A.
- Sebastian A.
- Sene D.
- Seror R.
- Shimizu T.
- Sis('o)-Almirall A.
- Solans-Laque R.
- Suzuki Y.
- Sz('a)nt('o) A.
- Takagi Y.
- Tarr T.
- V('a)zquez M.
- Valim V.
- Vissink A.
- Vollenveider C.
- Wahren-Herlenius M.
- Wiland P.
- Xu B.
- Yan Z.
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Objective: To characterize 414 patients with primary SS who developed haematological malignancies and to analyse how the main SS- and lymphoma-related features can modify the presentation patterns and outcomes. Methods: By January 2021, the Big Data Sjögren Project Consortium database included 11 966 patients fulfilling the 2002/2016 classification criteria. Haematological malignancies diagnosed according to the World Health Organization (WHO) classification were retrospectively identified. Results: There were 414 patients (355 women, mean age 57 years) with haematological malignancies (in 43, malignancy preceded at least one year the SS diagnosis). A total of 376 (91%) patients had mature B-cell malignancy, nearly half had extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT lymphoma) (n = 197), followed by diffuse large B-cell lymphoma (DLBCL) (n = 67), nodal MZL lymphoma (n = 29), chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) (n = 19) and follicular lymphoma (FL) (n = 17). Rates of complete response, relapses and death were 80%, 34% and 13%, respectively, with a 5-year survival rate of 86.5% after a mean follow-up of 8 years. There were significant differences in age at diagnosis (younger in MALT, older in CLL/SLL), predominant clinical presentation (glandular enlargement in MALT lymphoma, peripheral lymphadenopathy in nodal MZL and FL, constitutional symptoms in DLBCL, incidental diagnosis in CLL/SLL), therapeutic response (higher in MALT lymphoma, lower in DLBCL) and survival (better in MALT, nodal MZL and FL, worse in DLBCL). Conclusion: In the largest reported study of haematological malignancies complicating primary SS, we confirm the overwhelming predominance of B-cell lymphomas, especially MALT, with the salivary glands being the primary site of involvement. This highly-specific histopathological scenario is linked with the overall good prognosis with a 5-year survival rate of nearly 90%
Informe 'La Marca Canadiense: La Violencia Y La Minerra Canadiense En Guatemala' (The Canada Brand: Violence and Canadian Mining in Guatemala)
- Author
- 58xx/
- A La NO
- Afp / La Prensa
- Agencia Boliviana De Informaci�n
- Al Jezeera English
- Alejandra Guti�rrez Valdiz�n
- Alejandro Diez
- Alejandro Guerrero
- Alejandro Guerrero
- Alex E Hern�ndez
- Alexander Zaitchik
- Aline Quispe
- Allan Robinson
- Aminist�a Por Ejemplo
- Aminist�a Por Ejemplo
- Amnesty International
- Amnist�a Internacional
- Anabella Sibri�n
- Anabella Sibri�n
- Anastasia Gubin
- Anbareli Espinonza
- Andr�s V�squez
- Andr�s V�squez
- Andy Hoffman
- Ap / Telemetro
- Ascendant Copper
- B2gold
- Barrick Gold
- Barrick Gold Corp
- Brent Patterson
- Brett Popplewell
- Canadďż˝ Frenteen
- Carlos Zorrilla
- Carlos Zorrilla
- Catherine Solyom
- Cecilia Jamasmie
- Cecilia Jamasmie
- Cecilia Jamasmie
- Cecilia Jamasmie
- Clar�n
- Colectivo Azul
- Colectivo De
- Colombiano
- Comisi�n Guatemalteca De Derechos Humanos
- Corp Mag Silver
- Criminalizan Calas
- Danielle Mackey
- Dario Aranda
- Dar�o Aranda
- David Bacon
- David Bacon
- David Bacon
- David Ball
- David Hill
- David Modersbach
- Dawn Paley
- Dawn Paley
- Diane Nelson
- Diario Libre
- Diego Cevallos
- Ecomiradas
- Ecuadorian Klippensteins
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- El Espectador
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- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
The value of open-source clinical science in pandemic response: lessons from ISARIC
- Author
- Aasiyah Rashan
- Aasmine Kaur
- Abdulrahman Al-Fares
- Abhijit Duggal
- Adam Betz
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agamemnon Bakakos
- Agn??s Meybeck
- Agn??s Sommet
- Agnieszka Oldakowska
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Haji Ab Rahman
- Ahmed Farooq
- Aidan Burrell
- Ailbhe Cullen
- Ailbhe Hayes
- Aine McCarthy
- Aine McElroy
- Aisha Kalsoom Mufti
- Aisling Gavin
- Aisling Murphy
- Aisling Murphy
- Akram Zaaqoq
- Al-Awwab Dabaliz
- Alan Hartman
- Alasdair Nazerali-Maitland
- Albert Groenendijk
- Alberto Cucino
- Alberto Sotto
- Alberto Uribe
- Alberto Zanella
- Albertus Beishuizen
- Aldo Rafael
- Aldric Manuel
- Alejandro Martin-Quiros
- Aleksander Rygh Holten
- Aleksandr Beljantsev
- Alessandra Martinelli
- Alessandra Notari
- Alex Browne
- Alex Nagrebetsky
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J. Mentzer
- Alexander King
- Alexander Zoufaly
- Alexandra Bedossa
- Alexandra Coelho
- Alexandra Sperry
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Alexandros Cavayas
- Ali Abbas
- Ali Ait Hssain
- Ali Hachemi
- Ali Liaquat
- Ali Raza
- Ali Rehan
- Alice Bogaarts
- Alicia Gonzalez
- Alif Adlan Mohd Thabit
- Alina Kalicinska
- Alison M. Meynert
- Alistair Nichol
- Allison McGeer
- Alpha Diallo
- Alphonsine Diouf
- AM Udara Lakshan Attanyake
- Am??lie Valran
- Amanda Corley
- Amanda Palacios
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amar Bhatt
- Ami Stuart
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- Amirul Asyraf
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- Amy Stone
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- Ana Marques
- Ana Martins
- Ana Motos
- Ana Raquel Maia
- Anant Kataria
- Anatoliy Gavrylov
- Anca Streinu-Cercel
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- Anders Tveita
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- Antonio Loforte
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- Anuraj Shankar
- Aoife Driscoll
- Aoife Kelly
- Aquiles Henriquez
- Arabella Fahy
- Ardiyan Apriyana
- Arianne Joy Corpuz
- Arie Zainul Fatoni
- Arjen M Dondorp
- Arnaud Scherpereel
- Ars??ne Kpangon
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- Azrina Ralib
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- Bambang Pujo Semedi
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- Dimitra Melia Myrodia
- Dinesh Kuriakose
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- Dominic So
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- Dorothea Rosenberger
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- Dounia Bouhmani
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- Dyah Kanyawati
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- Ebenezer Rabindrarajan
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- Edel Meaney
- Eder Caceres
- Edmund Manning
- Edouard Soum
- Edward Wilson Grandin
- Efstathia Mihelis
- Eglantine Ferrand Devouge
- Egle Saviciute
- Eibhilin Higgins
- Eka Yudha Lantang
- Elaine Conway
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- Emmanuel Roilides
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- Emmanuelle Denis
- Emmanuelle Mercier
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- Erlina Burhan
- Erni Nelwan
- Ernita Akmal
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- Esteban Garcia-Gallo
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- Etienne De Montmollin
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- Ewa Talarek
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- F??lix Djossou
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- Fabio Guarracino
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- Fabrice Laine
- Fakhir Haidri
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- Federico D'Amico
- Felwa Bin Humaid
- Fernando Augusto Bozza
- Fernando Maltez
- Fernando Rainieri
- Ferran Roche-Campo
- Ferruccio Mele
- Filipa Br??s Monteiro
- Filipa Cardoso
- Filipa Sequeira
- Filipe Cardoso
- Filomena Boccia
- Fiona Griffiths
- Fionnuala O Brien
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- Florence Jego
- Florent Peelman
- Florentia Kaguelidou
- Fr??d??rick D???Aragon
- Fran??ois Angoulvant
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- Fran??ois Goehringer
- Fran??ois Lamontagne
- Fran??ois Lellouche
- Fran??ois Martin Carrier
- Fran??ois T??oul??
- Fran??ois-Xavier Catherine
- Fran??ois-Xavier Ferrand
- Fran??ois-Xavier Lescure
- France Mentr??
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- Frank Manetta
- Frank Olav Pettersen
- Fredrik Muller
- Gabriel Macheda
- Gabriel Suen
- Gabriele Sales
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- Gail Carson
- Galyna Kutsyna
- Gamage Dona Dilanthi Priyadarshani
- Gan Ee Xian
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- Gayle Carney
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- Gezy Giwangkancana
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- Giuseppe Foti
- Gloria Crowl
- Gr??gory Corvaisier
- Graham S. Cooke
- Grainne HigginsOKeeffe
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- Gregory Purcell
- Gretchen Lemmink
- Gry Kloumann Bekken
- Gugapriyaa Muyandy
- Guillame Louis
- Guillaume Lingas
- Guillaume Martin-Blondel
- Guillermo Giordano
- Guillermo Maestro de la Calle
- Guylaine Castor-Alexandre
- Gwena??l Le Moal
- Gwenha??l Colin
- Gyan Sandhu
- H M Upulee Pabasara
- H??l??ne Esperou
- H??l??ne Salvator
- Ha Sha Lene
- Haixia Shi
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- Hanan Fateena
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- Henk Vanoverschelde
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- Hernando Torres-Zevallos
- Herv?? Le Nagard
- Hiba Zayyad
- Hikombo Hitoto
- Himed Musaab
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- Hiroaki Shimizu
- Hiroyuki Tanaka
- Hiu Jian Chua
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- Huda Taqdees
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- Hugo Mouquet
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- Hussain Tanveer
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- Ikram Houas
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- Ingrid G. Bustos
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- Issrah Jawad
- Ithan D. Peltan
- Ivo Castro
- J Kevin Baird
- J. Kenneth Baillie
- J. Perren Cobb
- J??r??me Dimet
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- J??r??mie Pasquier
- Jack Song Chia
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- Jean-Charles Gagnard
- Jean-Charles Preiser
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- Jean-Fran??ois Timsit
- Jean-Luc Diehl
- Jean-Marc Chapplain
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- Jo Dalton
- Jo??o Alves
- Jo??o Cam
- Jo??o Estev??o
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- Jo??o Melo Alves
- Jo??o Oliveira
- Jo??o Teixeira
- Joan G??mez-Junyent
- Joana Ferr??o
- Joanne Downey
- Joao Joao Mendes
- Joaqu??n Baruch
- Jodat Saleem
- Jodat Saleem
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- Johannes Gebauer
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- John F. Fraser
- John G. Laffey
- John Marshall
- Johnny McKeown
- Jolanta Popielska
- Jonathan Chua
- Jonathan Crump
- Jonathan Golob
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- Jonathan Samuel Ch??vez I??iguez
- Jordan Zhien Yang Toh
- Jordi Rello
- Jordi Riera
- Jorge Dantas
- Jorge Fernandes
- Jorge Paulos
- Jos?? Casimiro
- Jos?? Ernesto Vidal
- Jos?? Luis Bernal Sobrino
- Jos?? Miguel Cisneros Herreros
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- Jose I Nunez
- Jose M. Mandei
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- Joshua Solomon
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- Kalynn Kennon
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- Koji Hoshino
- Kok Wei Hao
- Kollengode Ramanathan
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- Kristian Tonby
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- Kyle Gomez
- Laetitia Bodenes
- Lai Hui Pang
- Lance C. W. Turtle
- Lara Absil
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- Lars Heggelund
- Lars S. Maier
- Laur??ne Azemar
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- Lorna Murphy
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- Lucie Le Fevre
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- Luis Felipe Reyes
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- Lukas Arenz
- Lysa Tagherset
- M Azhari Taufik
- M??lanie Roriz
- M??rio Ferraz
- Ma??der Pagadoy
- Machteld van der Feltz
- Madiha Hashmi
- Maeve Kelsey
- Maeve Kernan
- Maeve Ryan
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- Maggie Mechlin
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- Maia Rabaa
- Maire-Laure Casanova
- Maisa Guimar??es de Castro
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- Malcolm G. Semple
- Malte Kohns Vasconcelos
- Mamoru Komatsu
- Mangala Narasimhan
- Manuel Etienne
- Manuel Rosa-Calatrava
- Maqsood Meher
- Mar??lia Fernandes
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- Marc Fabre
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- Marcel van den Berge
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- Marco Giani
- Mare Pejkovska
- Margarida Torres
- Margarite Grable
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- Maria Amaral
- Maria Angelica Rivera Nu??ez
- Maria Boylan
- Maria de Piero
- Maria Donnelly
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- Maria Joao Silva
- Maria Lawrensia Tampubolon
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- Mobin Chaudary
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- Muhammad Fadhli Hassin Basri
- Muhammad Hayat
- Mukesh Kumar
- Murray Dryden
- Murray Wham
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- Myung Jin Song
- Nad??ge Neant
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- Naoki Shimizu
- Naseem Ali Shah
- Nasir Khoso
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- Naveed Latif
- Navy Lolong
- Navya Garimella
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- Neurinda Permata Kusumastuti
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- Ng Yong Muh
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- Niamh Feely
- Niamh Kelly
- Niamh Ni Leathlobhair
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- Nik Nur Eliza Mohamed
- Nikita A Nekliudov
- Nilar Lwin
- Nina Buchtele
- Nina Jamieson
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- Nisreen Shiban
- No??mie Mercier
- No??mie Tissot
- No??mie Vanel
- Nobuaki Shime
- Nobuya Kitamura
- Noelia Garc??a Barrio
- Noor Hidayu Wahab
- Nor Arisah Misnan
- Nor Zaila Binti Zaidan
- Nora Fuentes
- Nuno Germano
- Nuno Martins
- Nur Amira
- Nurnaningsih Nurnaningsih
- Nurul Amani Mohd Noordin
- Nurul Faten Izzati Norharizam
- Nurul Najmee Abdulkadir
- Nurul Zaynah
- Oana Sandulescu
- Obada Yousif
- Odile Launay
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- Olivier Terrier
- Omar Mehkri
- Ong Yiaw Joe
- Oriane Pu??chal
- Orna Ni Choileain
- Oryane Mabiala
- Osama Khalid
- Osama Metwally
- Oscar Hoiting
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- Pablo Blanco-Schweizer
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- Paddy Mallon
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- Pavan Kumar Vecham
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- Rob Klont
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- Rog??rio Silva
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- Rui Gomes
- Rui Pereira
- Rumaisah Satyawati
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- Ruth N. Jorge Garc??a
- Ryadh Pokeerbux
- Ryan Kennedy
- Ryan Khoo
- Ryan S. Thwaites
- Ryuzo Abe
- S??bastien Preau
- S??lvia Ferreira
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- Saad Nseir
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- Segol??ne Greffe
- Senthilkumar Alegesan
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- Shaikh Sharjeel
- Shakeel Ahmed
- Shaminee Veeran
- Sharma Keshav
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- Sheryl Ann Abdukahil
- Shingo Adachi
- Shinichiro Ohshimo
- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shoban Raj Vasudayan
- Shona C. Moore
- Sia Loong Tonnii
- Silvia Casta??eda
- Silvia Lourenco
- Sim Choon Ean
- Sim??o Rodeia
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- Sobia Masood
- Sof??a Contreras
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- Suwarti Suwarti
- Suzanne Bennett
- Suzette Willems
- Swagata Tripathy
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
- Syed Muneeb
- Sylvain Diamantis
- Sylvie Behilill
- Sylvie LeGac
- Sylvie Lion-Daolio
- Sylvie Van Der Werf
- Synne Jenum
- Sze Kye Teoh
- T. Eoin West
- T??nia Sequeira
- Tae Song
- Taha Pasha
- Tahira Jamal Mohamed
- Tak-Hyuk Oh
- Takako Akimoto
- Takayuki Ogura
- Taku Tanaka
- Takuya Shiga
- Tala Al-dabbous
- Tamara Seitz
- Tan Pei Wen
- Tanvir Alam
- Tarek Elshazly
- Tatiana Fonseca
- Tatsuya Kawasaki
- Tawnya Ogston
- Teck Fung Wong
- Teresa Lawrence
- Terese Hammond
- Tessa Broadley
- Th??o Treoux
- Thalha Rashan
- Tharmini Ravi
- Tharwat Aisa
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Tiago Reyes
- Tiffany Trouillon
- Timo Brandenburger
- Timo Tolppa
- Ting Soo Chow
- Tiphaine Goulenok
- Tjard Schermer
- Todd C. Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Triona Downer
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- V??ctor Quir??s Gonz??lez
- V??ronique Lemee
- Vadim Tieroshyn
- Val??rie Gaborieau
- Val??rie Garrait
- Val??rie Gissot
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- van der Palen Job
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Manda
- Victoria McEneany
- Victoria Shaw
- Vieri Parrini
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Vladislav Mihnovit
- Volkan Korten
- Waasila Jassat
- Wai Ching Sin
- Walter Picard
- Wan Fadzlina Wan Muhd Shukeri
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xavier S??nchez Choez
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Yock Ping Chow
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zubair Umer
- Zul Amali Che Kamaruddin
- Zul Fakar
- Zulfiqar Sandhu
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
International audienc