Epidemiological and clinical features of patients with WD

<p>Footnotes: PAS = Periodic acid-Schiff staining, IHC = Immunohistochemistry performed using polyclonal rabbit anti-<i>T. whipplei</i> antibodies, PCR = Polymerase chain reaction, WL = Weight Loss, AP Abdominal Pain</p

Clinical manifestations and circulating IL-16 and apoptosis markers.

<p>A and B, Circulating levels of IL-16 (A) and nucleosomes (B) in untreated patients with intestinal manifestations of WD, ulcerative colitis and Crohn's disease. C and D, Circulating levels of IL-16 (C) and nucleosomes (D) in untreated patients with cardiac (Endo WD) or neurological manifestations of WD, and Q fever endocarditis (Endo QF). Results are expressed as individual values with medians.</p

Effect of antibiotic treatment on circulating levels of IL-16 and nucleosomes.

<p>A and B, Circulating levels of IL-16 (A) and nucleosomes (B) in patients successfully treated and patients who suffered from relapses. C and D, Time course of circulating IL-16 (♦) and nucleosomes (□) in two patients with neurological manifestations of WD who suffered from relapses. ↑ represents the date of clinical relapses.</p

High Ancient Genetic Diversity of Human Lice, <i>Pediculus humanus</i>, from Israel Reveals New Insights into the Origin of Clade B Lice - Fig 1

<p><b>Recovery of ancient human head lice from a two-sided louse comb belonging to the Roman period (A) recovered from the Judean desert and Arava regions of Israel</b>. In the lower part, entire specimens (B and C), the head and thorax of a head louse (D) and a damaged non-operculated egg (E) can be seen.</p

High Ancient Genetic Diversity of Human Lice, <i>Pediculus humanus</i>, from Israel Reveals New Insights into the Origin of Clade B Lice - Fig 1

<p><b>Recovery of ancient human head lice from a two-sided louse comb belonging to the Roman period (A) recovered from the Judean desert and Arava regions of Israel</b>. In the lower part, entire specimens (B and C), the head and thorax of a head louse (D) and a damaged non-operculated egg (E) can be seen.</p

Maximum-likelihood (ML) phylogram of contemporary and ancient haplotypes of <i>Pediculus humanus</i> based on the partial 272-bp cytb gene with <i>Pediculus schaeffi</i> (KC241883) and <i>Pthirus pubis</i> (EU219990) as outgroups.

<p>Maximum-likelihood (ML) phylogram of contemporary and ancient haplotypes of <i>Pediculus humanus</i> based on the partial 272-bp cytb gene with <i>Pediculus schaeffi</i> (KC241883) and <i>Pthirus pubis</i> (EU219990) as outgroups.</p

Summary of ancient samples, DNA analyses and haplotypes assignment.

<p>Summary of ancient samples, DNA analyses and haplotypes assignment.</p

<i>Cytb</i> haplotype networks of contemporary and ancient human body and head lice.

<p>Each circle area indicates a unique haplotype and variations in circle size are proportional to haplotype frequencies. Pie colors and sizes in circles represent the continents and the number of their sequence for a haplotype. The length of the links between nodes is proportional to mutational differences.</p

Pathogenic agents detected from infested homeless population in three localities, northern Algeria.

<p>Pathogenic agents detected from infested homeless population in three localities, northern Algeria.</p

Phylogenetic position of identified genotypes of <i>C</i>. <i>burnetii</i>, the agent of Q fever.

<p>The concerned sequences (COX2, 5 and 18) were aligned using CLUSTALW, and phylogenetic inferences was conducted in MEGA 6 using the maximum likelihood method, with the complete deletion option, based on the Kimura 2-parameter for nucleotide sequences. There was a total of 1,247 positions in the final dataset.</p