Coping Difficulties After Hospitalization

Coping difficulties of 113 adults 3 weeks after hospital discharge were identified using the Post-Discharge Coping Difficulty Scale and a brief focused telephone interview (11-item guide). Overall, low difficulty scores were reported (M = 23.9, SD = 18.2, range = 0 to 100). Qualitative data reveal specific coping difficulties in the categories of stressors, specific difficulties, caring for self, managing the condition, family, advice needed, contact with the health care system, and what they wished they knew before discharge. A core theme of biographical reconstruction emerged

Perceived Cognitive Changes with Chemotherapy for Breast Cancer: A Pilot Study

Purpose The purpose of this study was to determine perceived cognitive functioning, fatigue, depression and general well-being among women before and after the initiation of chemotherapy for breast cancer compared to a sample of healthy women. Method This descriptive, repeated measures study compared women receiving chemotherapy and healthy women. Women completed measures of quality of life, fatigue, cognitive changes and depression. Results Before chemotherapy, women with cancer reported more fatigue and depression than healthy women. After chemotherapy, women with cancer reported decreased cognitive functioning accompanied by more fatigue and depressive symptoms than healthy women. Conclusion This study is one of the first to use multiple symptom measures before and after starting chemotherapy. Understanding cognitive changes and related symptoms that occur before and during chemotherapy for breast cancer is the first step toward helping women cope with changes that occur with breast cancer treatment

Marshall University Music Department Presents a Senior Recital, James Robinson, Baritone, Linda Fitzgerald, Piano

https://mds.marshall.edu/music_perf/1162/thumbnail.jp

Safety and Efficacy of Biologic Agents for the Management of Inflammatory Bowel Disease After Liver Transplantation

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141779/1/phar2036.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141779/2/phar2036_am.pd

The cloning and reconstitution of a bovine adenovirus type 2 E3 deletion mutant and the sequencing and analysis of the early 4 region

Recombinant Adenoviruses (Ads) have been shown to have potential applications in three areas: gene therapy, high level protein expression and recombinant vaccines.' At least three different locations within the Ad genome can be deleted and subsequently used for the insertion of foreign sequences. These include the Early 3 (E3), Early 1 (E1) and Early 4 (E4) regions. Viral vectors of this type have been well studied in Human Ads 2 and 5, however one has not yet been constructed for Bovine Adenovirus Type 2 (BAV2). The E3 region is located between 76.6 and 86 m.u. on the r-strand and is transcribed in a rightward direction. The gene products of the Early 3 region (E3) have been shown to be non-essential for viral replication, in vitro, but are required for host immunosurveillance. This study represents the cloning and reconstitution of a BAV2 E3 deletion mutant. A deletion of 1800bp was made within the E3 region of BAV2 and the thymidine kinase gene was subsequently inserted in the deleted area . . The plasmid pdlE3-4tk1 (23.4Kbp) was constructed and used to to facilitate homologous recombination with the wild type BAV2 to produce a mutant. Southern Blotting and Hybridization results suggest the presence of a BAV2 E3 deletion mutant with thymidine kinase sequences present. The E4 region of Human Adenovirus types 2 and 5 is located at the extreme right end of the genome (91.3 map units - 99.1 map units) and is transcribed in a leftward direction giving rise to a complicated set of differentially spliced mRNAs. Essentially there are 7 open reading frames (ORFs) encoding for at least 7 polypeptides. The gene products encoded by the E4 region have been shown to be essential for the expression of late viral genes, host cell shutoff and normal viral growth. We have cloned and sequenced the right end segment between 90.5 map units and 100 map units of the BAV2 genome. The results show several open reading frames which encode polypeptides exhibiting homology to three polypeptides encoded by the E4 region of human adenovirus type 2. These include the 14kDa protein encoded by ORF1, the 34kDa protein encoded by ORF6 and the 13kDa protein encoded by ORF3. The nucleotide sequence, restriction enzyme map, and ORF map of the E4 region could be very useful in future molecular manipulation of this region and could possibly explain the slow growth rate of BAV2 in MDBK cells

RAPS - Student level outcomes of a positive youth development intervention to put public health data into action

The Risk/Resiliency Assessment Project for Students (RAPS) uses a positive youth development approach to engage students directly in the analysis and reporting of their school’s 2011 NM-YRRS data. Participants were 35 high school students from two Albuquerque area high schools who attended a day-long project retreat. Survey metrics included pre/post tests for critical health literacy, participant sense of community engagement, and pre/post assessment of student self-efficacy and civic attitudes. Survey items were derived from The Measure of Service Learning: Research Scales to Assess Student Experiences.https://digitalrepository.unm.edu/prc-posters-presentations/1008/thumbnail.jp

Translating a Human Rights-based Approach into Health and Social Care Practice

The aim of this work was to translate the legalistic nature of human rights into a practical way of working for those working across health and social care services in Ireland. In particular, it aimed to identify specific barriers to implementation of a human rights-based approach (HRBA) to care, most notably in terms of gaps in knowledge of frontline staff and to develop practical resources such as guidance to show how they can respect, promote and uphold people’s rights. A comprehensive literature review was undertaken and extensive engagement with health and social care stakeholders including, staff, advocates, and adults who use health and social care services was conducted. Stakeholder engagement consisted of public consultations, focus groups, and convening an advisory group. Findings from the literature review and the stakeholder engagement indicate that a lack of understanding regarding how to implement and practically apply a HRBA exists among frontline staff and management in health and social care services. It was identified there was a need to develop guidance to support health and social care staff in understanding a HRBA to care and support and to assist them in the implementation and application of human rights principles in their everyday work