23,691 research outputs found
The American Catholic: Contraception and Abortion
Dr. FitzGerald looks at the position in which social and environmental pressures, widespread contraception and the new therapeutic range of the prostaglandins have placed the American Catholic
Strategic motivators and expected benefits from e-Commerce in traditional organisations
This paper aims to identify the strategic motivators and expected benefits related to the implementation of e-commerce infrastructures in traditional “brick and mortar” organisations. Despite the fact that the clearest benefit from e-commerce might be expected to come from contribution to corporate profits, either from an increase of sales or reduction of costs, but this may not be the case. The literature suggests that there are different ways in which the potential benefits can be assessed. These ways are directly related to the evolution of e-commerce. This research has chosen six representative organisations from different sectors to explore their rationales for their e-commerce strategies. One of the main benefits reported is to increase the focus on the customer and improving internal communications. Additionally, obtaining competitive advantage was found to be a powerful motivator, despite the fact that the recent academic literature suggests that this is very difficult to achieve
Gastroprotective effects of oral nucleotide administration
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health. However, there has been only limited scientific study regarding the true biological activity of orally administered nucleotides. We therefore tested their efficacy in a variety of models of epithelial injury and repair. METHODS: Effects on proliferation ([(3)H] thymidine incorporation) and restitution (cell migration of wounded monolayers) were analysed using HT29 and IEC6 cells. The ability of a nucleotide mixture to influence gastric injury when administered orally and subcutaneously was analysed using a rat indomethacin (20 mg/kg) restraint model. RESULTS: In both cell lines, cell migration was increased by approximately twofold when added at 1 mg/ml (p<0.01); synergistic responses were seen when a mixture of nucleotides was used. Cell proliferation was stimulated by adenosine monophosphate (AMP) in HT29, but not in IEC6, cells. Gastric injury was reduced by approximately 60% when gavaged at 4–16 mg/ml (p<0.05), concentrations similar to those likely to be found in consumers taking nucleotide supplements. Systemic administration of nucleotides was unhelpful. CONCLUSIONS: Nucleotides possess biological activity when analysed in a variety of models of injury and repair and could provide a novel inexpensive approach for the prevention and treatment of the injurious effects of non steroidal anti‐inflammatory drugs and other ulcerative conditions of the bowel. Further studies on their potential benefits (and risks) appear justified
An assessment of apple varieties for their suitability in organic production systems
Twenty seven varieties of apple were assessed for their susceptibility to apple scab,
mildew and rosy apple aphid in a replicated experiment at East Malling Research. The
varieties most affected by mildew were Goldrush, DL11, Liberty, Bohemia and Pinova.
Ceeval, Discovery, Edward VII, Howgate Wonder, Rajka, Rebella and Topaz had the
lowest incidences of mildew. The highest incidence of scab occurred on Pilot and Pinova,
but infestation was low throughout the assessment period. In 2006 when aphid populations
were high, Liberty, Goldrush and Delorina had no aphid infestations, and low infestations
were seen on Edward VII, Resi and Santana
The Economic Value of A Passport: A Model of Citizenship and the Social Dividend in a Global Economy -
In a world of fully mobile capital and highly immobile labour, citizenship is effectively an entitlement to the 'dividend' arising from the social infrastructure accumulated in a particular country of birth. The paper opens with the reasons why the passport (ie citizenship) can in consequence be considered as an economic asset with a value that can in principle be determined analytically. A simple endogenous growth model is set up which defines the level and growth of per capita income in a world economy where capital is fully mobile and labour is fully immobile, and where governments set a rate of taxation such as to achieve the optimal balance between the stocks of private capital and social infrastructure. The 'passport value' is then defined as the difference between national income net of capital charges, wage costs and taxes when divided equally among the population; and is shown to depend on per capita income, the rate of growth and the parameters of the production function. A preliminary estimate of the main variables in the model, and the scale of expenditure on social infrastructure, for a wide range of countries suggests what the order of magnitude of the 'value of a passport' might be. A brief section on the wider implications of the findings concludes.
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