2,783 research outputs found

    Soliciting Sophisticates: A Modest Proposal for Attorney Solicitation

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    This Note advocates an amendment to the ethical standards governing attorneys that will permit the personal solicitation for pecuniary gain of sophisticated prospective clients - that is, those persons having general knowledge of their legal needs and the expertise to assess adequately the information and presentation of an attorney. Part I of this Note shows that lawyer solicitation is a form of commercial speech under recent Supreme Court decisions. It also asserts that, though the traditional reasons for banning lawyer solicitation still have some validity, these reasons do not justify prohibiting the solicitation of sophisticated clients. Part II suggests some potential benefits to the legal profession and clients resulting from the proposed solicitation amendment. In Part III, this Note offers a bright-line standard for sophistication that the bar might apply to this amendment so that lawyers can better determine the propriety of their activities. Finally, this Note concludes that adopting the amendment to permit the solicitation of sophisticated persons will not drastically change the way lawyers attract new clients, and will benefit both lawyers and consumers of legal services by recognizing their legitimate commercial speech interests

    Transfected poly(I:C) activates different dsRNA receptors leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells

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    Background: Castration-resistant prostate cancer (CRPC) is refractory to chemo-radiotherapy. Results: Transfection of the synthetic analog of dsRNA poly(I:C) simultaneously stimulates apoptosis and IFN- expression through different pathways in androgen-independent prostate cancer (PCa) cells. Conclusion: Dual parallel pathways triggered by distinct receptors activate direct and immunologically mediated antitumor effects in advanced PCa. Significance: The proapoptotic/immunoadjuvant poly(I:C)-Lipofectamine complex may offer new therapeutic insights into CRPC

    Upper critical field in {Ba1−x_{1-x}Kx_xBiO3_3}: magnetotransport versus magnetotunneling

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    Elastic tunneling is used as a powerful direct tool to determine the upper critical field Hc2(T)H_{c2}(T) in the high-TcT_c oxide Ba1−x_{1-x}Kx_xBiO3_3. The temperature dependence of Hc2H_{c2} inferred from the tunneling follows the Werthamer-Helfand-Hohenberg prediction for type-II superconductors. A comparison will be made with resistively determined critical field data.Comment: 4 pages incl. 5 figure

    Analytical formulas for calculating the thermal diffusivity of cylindrical shell and spherical shell samples

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    Calculating the thermal diffusivity of solid materials is commonly carried out using the laser flash experiment. This classical experiment considers a small (usually thin disc-shaped) sample of the material with parallel front and rear surfaces, applying a heat pulse to the front surface and recording the resulting rise in temperature over time on the rear surface. Recently, Carr and Wood [Int J Heat Mass Transf, 144 (2019) 118609] showed that the thermal diffusivity can be expressed analytically in terms of the heat flux function applied at the front surface and the temperature rise history at the rear surface. In this paper, we generalise this result to radial unidirectional heat flow, developing new analytical formulas for calculating the thermal diffusivity for cylindrical shell and spherical shell shaped samples. Two configurations are considered: (i) heat pulse applied on the inner surface and temperature rise recorded on the outer surface and (ii) heat pulse applied on the outer surface and temperature rise recorded on the inner surface. Code implementing and verifying the thermal diffusivity formulas for both configurations is made available.Comment: 12 pages, 5 figure

    Agroecology in the curricula of the Faculty of Agricultural Sciences of the UNCUYO : contributions to the territorial planning

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    Fil: Studer, P. M.. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de Ingeniería AgrícolaFil: Viani, M. . Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de Ingeniería AgrícolaFil: Filippini, María Flavia. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias. Departamento de Ingeniería Agrícol

    Constraints on Dark Matter from Colliders

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    We show that colliders can impose strong constraints on models of dark matter, in particular when the dark matter is light. We analyze models where the dark matter is a fermion or scalar interacting with quarks and/or gluons through an effective theory containing higher dimensional operators which represent heavier states that have been integrated out of the effective field theory. We determine bounds from existing Tevatron searches for monojets as well as expected LHC reaches for a discovery. We find that colliders can provide information which is complementary or in some cases even superior to experiments searching for direct detection of dark matter through its scattering with nuclei. In particular, both the Tevatron and the LHC can outperform spin dependent searches by an order of magnitude or better over much of parameter space, and if the dark matter couples mainly to gluons, the LHC can place bounds superior to any spin independent search.Comment: 23 pages, 16 figure

    Simplified models of diffusion in radially-symmetric geometries

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    We consider diffusion-controlled release of particles from dd-dimensional radially-symmetric geometries. A quantity commonly used to characterise such diffusive processes is the proportion of particles remaining within the geometry over time, denoted as P(t)P(t). The stochastic approach for computing P(t)P(t) is time-consuming and lacks analytical insight into key parameters while the continuum approach yields complicated expressions for P(t)P(t) that obscure the influence of key parameters and complicate the process of fitting experimental release data. In this work, to address these issues, we develop several simple surrogate models to approximate P(t)P(t) by matching moments with the continuum analogue of the stochastic diffusion model. Surrogate models are developed for homogeneous slab, circular, annular, spherical and spherical shell geometries with a constant particle movement probability and heterogeneous slab, circular, annular and spherical geometries, comprised of two concentric layers with different particle movement probabilities. Each model is easy to evaluate, agrees well with both stochastic and continuum calculations of P(t)P(t) and provides analytical insight into the key parameters of the diffusive transport system: dimension, diffusivity, geometry and boundary conditions.Comment: 22 pages, 3 figures, submitte
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