17 research outputs found

    Homeostasis Meets Motivation in the Battle to Control Food Intake.

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    Signals of energy homeostasis interact closely with neural circuits of motivation to control food intake. An emerging hypothesis is that the transition to maladaptive feeding behavior seen in eating disorders or obesity may arise from dysregulation of these interactions. Focusing on key brain regions involved in the control of food intake (ventral tegmental area, striatum, hypothalamus, and thalamus), we describe how activity of specific cell types embedded within these regions can influence distinct components of motivated feeding behavior. We review how signals of energy homeostasis interact with these regions to influence motivated behavioral output and present evidence that experience-dependent neural adaptations in key feeding circuits may represent cellular correlates of impaired food intake control. Future research into mechanisms that restore the balance of control between signals of homeostasis and motivated feeding behavior may inspire new treatment options for eating disorders and obesity

    BEAM SLICE CHARACTERIZATION AT SPARC HIGH BRIGHTNESS PHOTOINJECTOR

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    The SPARC photoinjector drives a SASE FEL to perform several experiments both for the production of high brightness electron beam and for testing new scheme of SASE radiation generation. The control of the beam properties, in particular at the level of the slice dimension, is crucial in order to optimize the FEL process. We report some preliminary results concerning slice emittance and slice energy spread measurements. A comparison with PARMELA simulation is also give

    BEAM SLICE CHARACTERIZATION AT SPARC HIGH BRIGHTNESS PHOTOINJECTOR

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    The SPARC photoinjector drives a SASE FEL to perform several experiments both for the production of high brightness electron beam and for testing new scheme of SASE radiation generation. The control of the beam properties, in particular at the level of the slice dimension, is crucial in order to optimize the FEL process. We report some preliminary results concerning slice emittance and slice energy spread measurements. A comparison with PARMELA simulation is also give
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