Why the students of fifth year of the morning shift at Salomón de la Selva high school in Managua have a low level of proficiency in speaking and pronunciation skills in English as a foreign language

Nowadays English language has been one of the most relevant educational factors in Nicaragua and the population is being demanded to acquire it as a second language to exchange our cultural, social, political and economical aspects with foreign countries. During many years students in high schools have been taking English as a part of the curriculum set by the minister of education and therefore used by the teachers in public schools. In this research, we intend to find out the reasons that cause a low level of proficiency in speaking and pronunciation skills that students have in the second language acquisition and mostly, we have observed that the students of fifth year at Salomón de la Selva high school have a lot of difficulties in speaking and pronunciation skills through the teaching and learning process in the classroom. The problem has aroused our interest to look for specific information to help us find a solution. We focus our attention on the possible factors that lead to the problem of our concern: the materials used in the classroom and the kind of techniques the teacher carries out in class in order to fulfill his objectives. Our work lets you know about the previous knowledge and the linguistic problems the students have in English. And also how this can negatively affect them during their learning process in their last level of secondary schoo

Diseño de un sistema de servicio para la planificación de materiales

El diseño de un proceso desde la perspectiva de un sistema de servicio debe tener presente la tecnología, información y personas. El reto no es solo modelar la interacción de información y tecnología, sino también los roles de las personas como parte del sistema (Maglio, Srinivasan, & Kreulen, 2006). Con la metodología de Gestión por Procesos del Negocio (Business Process Management BPM) y los aportes de la óptica del servicio como guía, en este trabajo se diseñó un sistema de servicio de planificación de materiales. Se identificó en su estructura la coproducción entre las personas y su relación con la tecnología de información. El objetivo fue demostrar cómo la formalización del sistema es un precursor para la disminución de desperdicios, ubicados en los retrabajos y tiempo de respuesta al cliente. La metodología BPM consta de una serie de fases para el modelado de procesos que visualiza los objetivos de la organización y cómo el proceso participa en la generación de valor; con esto, brindar soluciones a clientes internos y externos, lo cual es lo más importante según la lógica dominante de servicio (Vargo & Lusch, 2004)

Meso-Neoproterozoic basic-intermediate mafic granulites (metabasites) from the ∼1 Ga granulitic southwestern Oaxacan complex, Mexico, crustal evolution and phase equilibria modeling

Altres ajuts: acords transformatius de la UABThe basement of eastern Mexico is made up of Grenvillian granulite-facies metamorphic rocks, which constitute an inferred microcontinent named Oaxaquia. Proto-Oaxaquia oceanic arc reconstructions are related to the transition from Columbia to Rodinia supercontinents (∼1.5 Ga). This study focuses on the petrography, geochemistry, and phase equilibria modeling of metabasites from the southwestern Oaxacan Complex, the largest Oaxaquia outcrop. Southwestern Oaxacan Complex protoliths mainly correspond to gabbro/basalt. They constitute an assemblage apart from the rest of the Oaxacan Complex metabasites due to their Ti enrichment and SiO2 depletion related to post-magmatic/metamorphic processes. Southern study site metabasites correspond to the primitive root of the arc, mostly related to a divergent geotectonic setting. The other metabasites are related to the magmatic back/forearc active margin between proto-Oaxaquia and Amazonia craton. Phase equilibria modeling point to Zapotecan (last Grenvillian cycle) metamorphic peak conditions of 850 ± 25 °C and 1.0 ± 0.15 GPa from one garnet-amphibole bearing metabasite, and a later hydration episode (post-Grenvillian) of 760 ± 10 °C and 0.8 ± 0.20 GPa derived from one amphibole bearing metabasite. The time of incipient partial melting of the southwestern Oaxacan Complex is a pre-Zapotecan event (∼1 Ga). Mineral textures do not display significant processes related to the post-Zapotecan metamorphic retrogression, and only a few whole-rock light rare element patterns display strong enrichments

Estilo personal del terapeuta y dirección de intereses

El objetivo principal del presente estudio es profundizar en el conocimiento del Estilo Personal del Terapeuta (EPT) y estudiar las relaciones entre diferentes funciones de este estilo y la dirección de intereses de los terapeutas en formación. E] EPT es evaluado con el cuestionario EPT-C (Fernández Álvarez, García, LoBianco y Corbella, 2003) que distingue seis funciones que permiten dibujar el perfil personal de cada terapeuta: instruccional, atencional, expresiva, operacional e involucrativa. La dirección de interés del terapeuta es evaluada a través del cuestionario DIQ (Caine. Wijesinghe y Winter. 1981) que distingue entre una dirección interna o externa, La muestra del estudio está formada por 9] licenciados 9.9% hombres y 90,1% mujeres) que están cursando un Máster en psicoterapia. Los resultados de los análisis indican unas correlaciones moderadas y significativas entre las funciones atencional (receptiva) y operativa (espontáneo) y la dirección de intereses (interna) de los participantes

Identification and characterization of the TonB region and its role in transferrin-mediated iron acquisition in Haemophilus parasuis

12 p.Haemophilus parasuis is the causative agent of Glässer's disease, which is responsible for considerable economic losses in the pigrearing industry. The aim of the study reported here was the identification, sequencing and molecular characterization of the TonB region that includes tonB, exbBD, and tbpBA genes in H. parasuis. In addition, two fusion proteins were generated. One of them (pGEX-6P-1-GST-TbpB) contained the first 501 amino acids of H. parasuis TbpB protein, while the second (pBAD-Thio-TbpBV5- His) included the first 102 amino acids of H. parasuis TbpB N-terminus domain. A panel of 14 hybridomas secreting monoclonal antibodies was raised against the two recombinant TbpB fusion proteins. Furthermore, to assess whether the expression of the H. parasuis ExbB, TbpB, and TbpA proteins was upregulated under conditions of restricted availability of iron, a rabbit polyclonal antibody against H. parasuis TbpB-His fusion protein was produced. A rabbit polyclonal antibody against serotype 7 of Actinobacillus pleuropneumoniae ExbB and TbpA proteins was also used for the detection of the homologous proteins in H. parasuis. Overall, the data indicate that H. parasuis, like other members of the Pasteurellaceae family, possesses the genetic elements of the TonB region for iron acquisition and the transferrin-binding proteins encoded under this region are upregulated under restricted iron availabilityS

Conflictos cognitivos en una muestra comunitaria: un estudio exploratorio

El estudio de los conflictos cognitivos se ha llevado a cabo desde diversas aproximaciones teóricas. En el ámbito de la Psicología de los Constructos Personales, la técnica de la rejilla ha permitido operativizar un tipo de conflicto cognitivo denominado Dilema Implicativo (DI) y estudiar su papel en el campo de la salud. En este trabajo se ha analizado la construcción del sí mismo, la estructura cognitiva y el malestar psicológico en personas con y sin DI pertenecientes a una muestra comunitaria. En la investigación participaron 115 sujetos (56.5% mujeres y 43.5% hombres). Las técnicas de evaluación utilizadas fueron la técnica de la rejilla, y las versiones españolas del Symptom Check List-90-R (SCL-90-R) y el Clinical Outcome in Routine Evaluation (CORE-OM). Los principales resultados revelan correlaciones positivas en las tres medidas del sí mismo, lo que supone una alta autoestima, aunque si se comparan los grupos con/sin DI, se observan correlaciones más bajas en las personas con dilemas. En cuanto a la complejidad cognitiva, las personas con dilemas muestran una estructura cognitiva más diferenciada. Por último, en relación con el malestar psicológico percibido, los dos grupos presentan puntuaciones dentro del rango de la normalidad aunque las personas sin DI se sienten en mayor sintonía consigo mismas/con los demás que las personas con dilemas, presentando estas últimas puntuaciones superiores en escalas de depresión y ansiedad del SCL-90, y en las medidas globales del CORE-O

Evaluation of DNA Single and Double Strand Breaks in Women with Cervical Neoplasia Based on Alkaline and Neutral Comet Assay Techniques

A hospital-based unmatched case-control study was performed in order to determine the relation of DNA single (ssb) and double (dsb) strand breaks in women with and without cervical neoplasia. Cervical epithelial cells of 30 women: 10 with low grade squamous intraepithelial lesions (LG-SIL), 10 with high-grade SIL (HG-SIL), and 10 without cervical lesions were evaluated using alkaline and neutral comet assays. A significant increase in global DNA damage (ssb + dsb) and dsb was observed in patients with HG-SIL (48.90 ± 12.87 and 23.50 ± 13.91), patients with LG-SIL (33.60 ± 14.96 and 11.20 ± 5.71), and controls (21.70 ± 11.87 and 5.30 ± 5.38; resp.). Pearson correlation coefficient reveled a strong relation between the levels ssb and dsb (2=0.99, =0.03, and 2=0.94, =0.16, resp.) and progression of neoplasia. The increase of dsb damage in patients with HG-SIL was confirmed by DNA breakage detection-FISH (DBD-FISH) on neutral comets. Our results argue in favor of a real genomic instability in women with cervical neoplasia, which was strengthened by our finding of a higher proportion of DNA dsb

First histopathological study in kidneys of rodents naturally infected with Leptospira pathogenic species from Yucatan, Mexico

AbstractObjectiveTo report the renal histological lesions in synanthropic rodents, Mus musculus and Rattus rattus, naturally infected with Leptospira spp., captured in a rural community in Yucatan, Mexico.MethodsKidney samples of synanthropic rodents were collected from a rural community in Yucatan, Mexico. Polymerase chain reaction was used to detect Leptospira spp. infection. Tissue kidney was fixed in 10% buffered formalin, processed according to the usual techniques for paraffin inclusion, cut and stained with hematoxylin and eosin, and examined using a conventional electronic microscope.ResultsA total of 187 rodents were captured. Nine individuals (4.8%) were positive for Leptospira spp. in the molecular analysis. All renal lesions observed in the histopathological study had been reported previously for Leptospira spp. infection.ConclusionsThe histopathological lesions are present in the kidneys, plus the results of the polymerase chain reaction confirm that these rodents are true carriers of Leptospira spp

Low lung function in Bipolar Disorder and Schizophrenia: a hidden risk

Introduction: People with serious mental illness (SMI), such as schizophrenia and bipolar disorder, have a higher risk of premature morbidity and mortality. In the general population, impaired lung function is associated with increased morbidity and mortality. We compared lung function between people with and without serious mental illnesses using a cross-sectional study in 9 community mental health units. Methods: Subjects aged 40-70 years with a diagnosis of schizophrenia or bipolar disorder were recruited consecutively. The controls had no psychiatric diagnosis and were not receiving any psychotropics. Spirometry was performed by a trained nurse. We used the 2021 American Thoracic Society/European Respiratory Society standards for the interpretation of the spirometry results. Results: We studied 287 subjects. People with SMI (n = 169) had lower spirometry values than those without a psychiatric diagnosis (n = 118). An abnormal spirometry pattern (36.1% vs 16.9%, p < 0.001), possible restriction or non-specific (Preserved Ratio Impaired Spirometry [PRISm]) pattern (17.8% vs 7.6%, p = 0.014), and pattern of airflow obstruction or possible mixed disorder (18.3% vs 9.3%, p = 0.033) were more frequent in people with SMI. Multivariate analyses showed that the PRISm pattern was associated with abdominal circumference (odds ratio [OR] 1.05, 95%CI 1.03-1.08) and that the pattern of airflow obstruction or possible mixed disorder was associated with smoking behavior (OR 5.15, 95%CI 2.06-15.7). Conclusion: People with SMI have impaired lung function, with up to one-third of them showing an abnormal spirometry pattern. This suggests that regular monitoring of lung function and addressing modifiable risk factors, such as tobacco use and obesity, in this population is of paramount importance