Analysis of a customer relationship management tool in a shipping company

Today’s society is technologically advanced, the world is just a click away and our companies’ customers have easy access to all the information. Therefore, they are increasingly demanding, wanting more and better at a lower cost. Using as a case study a shipping company, a system of Customer Relationship Management (CRM) was analysed to verify what reasons led to its abandonment and to realise what to do to reverse such situation. In this industry product differentiation is practically null, so the customer’s choice comes down to price. However, customers are paying more attention to customer service, therefore companies are developing stronger relationships with them. The construction of such relationships implies data collection on the client, from which one can offer services of greater value. This may lead to partnerships and competitive advantages. Thus, the use of CRM tools is being promoted for CRM tools present themselves as a valuable asset. In the end, suggestions are presented, ranging from improvements to the existing system, to more complex suggestions, costlier or breaking with the existing mode of relationship and dialogue between company and customers, but that, in the future, will certainly translate into advantages over competing companies.info:eu-repo/semantics/publishedVersio

A multicriteria decision model for the selection of information system for a logistics company using MMASSI/TI

The aim of this work is to apply a methodology of decision support based on a multi-criteria decision analyses (MCDA), model that allows the evaluation and selection of an information system in a Logistics context. We carried out a literature review on supply chain management, logistics and decision theory to support all the practical work. A multi-criteria methodology for decision making support – Multi-criteria Methodology for the Assessment and Selection of Information Systems / Information Technologies (MMASSI / IT) based on logistics processes was applied during the MCDA, supported by a computer application. The ranking of the information systems best suited the decisional context was obtained and its sensitivity and robustness analyses performed.info:eu-repo/semantics/publishedVersio

Chitosan coating functionalized with flaxseed oil and green tea extract as a bio-based solution for beef preservation

Ecological and safe packaging solutions arise as pivotal points in the development of an integrated system for sustainable meat production. The aim of this study was to assess the effect of a combined chitosan (Ch) + green tea extract (GTE) + essential oil (thyme oil, TO; flaxseed oil, FO; or oregano oil, OO) coating on the safety and quality of vacuum-packaged beef during storage at 4 °C. An optimized bio-based coating formulation was selected (2% Ch + 2% GTE + 0.1% FO) to be applied to three fresh beef cuts (shoulder, Sh; knuckle, Kn; Striploin, St) based on its pH (5.8 ± 0.1), contact angle (22.3 ± 0.4°) and rheological parameters (viscosity=0.05 Pa.s at shear rate > 20 s−1). Shelf-life analysis showed that the Ch–GTE–FO coating delayed lipid oxidation and reduced total viable counts (TVC) and Enterobacteriaceae growth compared with uncoated beef samples over five days. In addition, Ch–GTE–FO coating decreased total color changes of beef samples (e.g., ∆E*=9.84 and 3.94, for non-coated and coated Kn samples, respectively) for up to five days. The original textural parameters (hardness, adhesiveness and springiness) of beef cuts were maintained during storage when Ch–GTE–FO coating was applied. Based on the physicochemical and microbial characterization results, the combination of the Ch–GTE–FO coating developed was effective in preserving the quality of fresh beef cuts during refrigerated storage along with vacuum packaging.This research was funded by ETHICAL MEAT—Integrated System for Sustainable Meat Production project (POCI-01-0247-FEDER-072254), co-financed by the European Regional Development Fund (ERDF) through Compete 2020–Competitiveness and Internationalisation Operational Programme (POCI). This work was also financially supported by FCT under the scope of the strategic funding of UIDB/04469/2020 unit, and by LABBELS—Associate Laboratory in Biotechnology, Bioengineering and Microelectromechanical Systems, LA/P/0029/2020.info:eu-repo/semantics/publishedVersio

Association Between Iron-Related Protein Lipocalin 2 and Cognitive Impairment in Cerebrospinal Fluid and Serum

A worldwide increase in longevity is bringing novel challenges to public health and health care professionals. Cognitive impairment in the elderly may compromise living conditions and precede Alzheimer's disease (AD), the most prevalent form of dementia. Therefore, finding molecular markers associated with cognitive impairment is of crucial importance. Lipocalin 2 (LCN2), an iron-related protein, has been suggested as a potential marker for mild cognitive impairment (MCI) and AD. This study aimed at investigating the association between LCN2 measured in serum and cerebrospinal fluid (CSF) with cognitive impairment. A cross-sectional design based on two aging cohorts was used: individuals diagnosed with subjective cognitive complaints (SCC), MCI, and AD from a Swedish memory clinic-based cohort, and individuals diagnosed with SCC and AD from a Portuguese cohort. Binary logistic [for the outcome cognitive impairment (MCI + AD) in the Swedish cohort and AD in the Portuguese cohort] and multinomial logistic (for the outcomes MCI and AD) regression analyses were used. No associations were found in both cohorts when controlling for sex, education, and age. This explanatory study suggests that the association between serum and CSF LCN2 concentrations with cognitive impairment reported in the literature must be further analyzed for confounders.info:eu-repo/semantics/publishedVersio

Preferência manual de crianças ao alcançar objetos de tamanho e rigidez diferentes

O estudo teve por objetivo analisar a preferência manual de crianças ao alcançar objetos de diferentes tamanhos nas idades de 4, 6, 8 e 36 meses. Para tanto, nove crianças saudáveis foram posicionadas em uma cadeira reclinada para trás a 50º com a horizontal e a elas foram apresentados quatro objetos de rigidez e tamanhos distintos. Foram coletados longitudinalmente 524 alcances aos 4, 6, 8 e 36 meses, sendo analisadas as variáveis mão preferida no alcance e índice de contribuição para os alcances bimanuais. Constatou-se que a mão preferida no alcance no decorrer dos meses foi a direita e que somente aos 6 meses o tamanho dos objetos influenciou a preferência manual: as crianças fizeram preferencialmente alcances com a mão direita para objetos pequenos, e mão esquerda para os grandes. Nos alcances bimanuais, constatou-se que, em geral, a mão que primeiro toca o objeto é a mão mais ativa durante todo o movimento de alcançar. Provavelmente porque a rigidez seja menos visualmente percebida do que o tamanho, só este influencia o alcance aos 6 meses, idade em que o lactente refina o movimento de alcance. O tamanho o influencia aos 6 meses, idade em que o movimento de alcançar se encontra em fase de refinamento: objetos pequenos que exigem maior precisão foram alcançados com a mão direita (mão preferida); e objetos grandes, que não exigem precisão para serem apreendidos, foram alcançados com a mão esquerda.The purpose of this study was to analyse infants' and toddlers' manual preference in reaching objects of different sizes and rigidity at the ages of 4, 6, 8, and 36 months. Four objects of different size and stiffness were presented to nine healthy infants leaning on a chair at 50º. A total of 524 reaching movements were analysed longitudinally to verify manual preference and the index of contribution of each hand for bimanual reaching. Results showed preference of the right hand for reaching objects; only at the age of 6 months the object size influenced manual preference: infants used preferably the right hand to reach small objects and the left one for large objects. The hand that first touched the object in bimanual reaching was the most active during reaching trajectory. These findings suggest that the size of the object - and not rigidity, which is less visually perceptible - influenced infants' reaching at the age of 6 months, that is, when reaching movement is being refined; small objects, which require more accuracy to be grasped, were reached with the right hand (preferred one)), whereas large objects which do not require accuracy to be grasped were reached with the left hand

Efficacy Of First Time Furosemide Use In Thoroughbred Racehorses In Brazil

Racehorses are commonly affected by a condition known as Exercise Induced Pulmonary Haemorrhage (EIPH) which consists of rupture of alveolar membranes and extravasation of blood into the airways. EIPH is considered to negatively affect racehorse performance and there is no current treatment. In order to reduce the amount of bleeding the diuretic furosemide has been used prior to exercise and competition in some racing jurisdictions. Efficacy of furosemide in reducing EIPH is documented in this research through endoscopic observation of the airways of horses positive for EIPH in two consecutive races

Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast

Metaplastic carcinomas of the breast (MCBs) are unusual neoplasms characterized by an admixture of glandular epithelial components, which frequently exhibit features of squamous differentiation, and mesenchymal malignant components. Regardless of the presence of myoepithelial features in MCB, no consensus concerning their putative histogenesis has yet been achieved. Recently, novel putative myoepithelial markers have been developed, including p63, maspin, and P-cadherin. We assessed the expression of these myoepithelial markers in MCBs and compared their expression with classic myoepithelial markers. Immunohistochemistry using the streptavidin– biotin–peroxidase complex technique with antibodies raised against p63, maspin, P-cadherin, actin (clones CGA7, 1A4 and HHF35), cytokeratin 14 (Ck14), and vimentin was performed on 16 MCBs (7 matrix-producing MCBs, 6 adenosquamous MCBs, and 3 MCBs with heterologous elements). In healthy breast lobules and ducts adjacent to the tumors, myoepithelial cells showed distinctive and consistent immunoreactivity for p63, maspin, P-cadherin, actin, S-100 protein, and Ck14. Matrix- producing MCBs were positive for maspin in all cases, for p63 in 4 of 7 cases, and for P-cadherin in 4 of 7 cases. Adenosquamous MCB showed immunoreactivity for p63, maspin, and P-cadherin in 5 of 6 cases. All novel myoepithelial markers and Ck14 decorated squamous cell islands. MCBs with heterologous elements were positive for p63 in 1 case, for maspin in all 3 cases, and for P-cadherin in 2 cases. All cases showed at least one of the novel myoepithelial markers. Eleven of 16 cases were positive for actin. Eleven of 14 cases reacted with Ck14, and all cases that stained for S-100 protein (9 of 9) and vimentin (13 of 13) were also positive. Based on our findings, the balance of probabilities favors that MCBs may have a basal or myoepithelial cell histogenesis and differentiation.Fundacão para a Ciência e a Tecnologia (FCT), Ministério da Ciência e Tecnologia (MCT) - SFRH/BD/5386/2001