Photoresponsive nutlin derivatives and uses thereof

The invention relates to the field of medicine and medicinal chemistry, more in particular to the design, manufacture and use of anti-cancer drugs that can be activated by an external stimulus that can be applied in a spatiotemporal fashion. Provided herein is a compound having the chemical structure or a pharmaceutically acceptable salt thereof

Probing the origin of fluorescence quenching of graphene-porphyrin hybrid material

We report transient absorption spectroscopic studies on the hybrid material composed of porphyrin molecules covalently attached to graphene for investigating the mechanism underlying the reported fluorescence quenching of porphyrin in the hybrid [1]. Excited state dynamics of pure graphene suspension and porphyrin have also been studied as reference samples. A fast excited state decay was observed in the hybrid