7,567 research outputs found
‘Us’ and ‘Them’: Ulster Loyalist Perspectives on the IRA and Irish Republicanism
This article draws on data from one-to-one interviews with members and former members of the Ulster Volunteer Force (UVF), Ulster Defence Association (UDA), Red Hand Commando (RHC), Ulster Political Research Group (UPRG) and the Progressive Unionist Party (PUP) to explore the dynamic and fluid perceptions of the Irish Republican Army (IRA) and Sinn Fein among Ulster Loyalists. The article will illustrate now attitudes and perceptions are influenced by the shifting political landscape in Northern Ireland as Ulster Loyalists come to terms with the new realities created by the peace-process, security normalization, decommissioning and the rise in the threat of dissident Republican violence. The also illustrate that these perceptions are not purely antagonistic and based on the creation of negative stereotypical ‘enemy images’ fuelled by decades of conflict, but pragmatic, bound to societal and local events and influenced intragroup attitudes and divisions in addition to the expected conflictual ingroup vs. outgroup relationships. Finally, the paper will explore how Loyalists employ Republicanism and the transformation of the Provisional IRA in particular, as a mirror or benchmark to reflect on their own progress since 1994
Staying Engaged in Terrorism: Narrative Accounts of Sustaining Participation in Violent Extremism
Research exploring radicalization pathways and how and why people become involved in terrorism has expanded since the 9/11 attacks. Likewise, over the last decade research exploring de-radicalization and desistence from terrorism has grown and expanded in an attempt to promote exit from extremist or terror groups. However, research studies on how individuals sustain engagement in terrorism and their involvement with extremist organizations, often in the face of great adversity, are absent from the body of research. To address this scarcity of research this study analyzed accounts of engagement in violent extremism produced by Northern Irish loyalist and republican paramilitaries in order to explore how their paramilitary lifestyle, perpetration of acts of political violence and the pressure from countering threats posed by rival groups, and the State security forces impacted on them. The analysis utilized a hybrid of thematic analysis and interpretative phenomenological analysis (IPA). The themes raised through the analysis reflected the psychological, social and economic hardship associated with this lifestyle. The narrative accounts also illustrated psychological changes associated to engagement in violence and from insulation within tightly knit extremist groups. As most of the participants faced incarceration during their paramilitary careers, themes also reflected on the impact imprisonment had on them. The themes explored factors that sustained their involvement, including the role of identity development and identity fusion in sustaining their extremism, the impact of insulated group membership, feelings of efficacy, dehumanization processes, community support, and beliefs in the utility of violence
Social movements, structural violence and conflict transformation in Northern Ireland: The role of Loyalist paramilitaries
This article analyses how social movements and collective actors can affect political and social transformation in a structurally violent society using the case study of Northern Ireland. We focus, in particular, on the crucial role played by collective actors within the loyalist community (those who wish to maintain Northern Ireland’s place in the UK), in bringing about social and political transformation in a society blighted by direct, cultural, and structural violence both during the conflict and subsequent peace process. Drawing on data obtained through in-depth interviews with loyalist activists (including former paramilitaries), the article demonstrates the role and impact of loyalists and loyalism in Northern Ireland’s transition. We identify five conflict transformation challenges addressed by loyalist actors in a structurally violent society: de-mythologizing the conflict; stopping direct violence; resisting pressure to maintain the use of violence; development of robust activist identity; and the measurement of progress through reference to the parallel conflict transformation journey of their former republican enemies. The Northern Ireland case demonstrates the necessity for holistic conflict transformation strategies which attempt not only to stop direct attacks, but also the cultural and structural violence which underpin and legitimize them. In so doing, the article contributes to a broader understanding of how and why paramilitary campaigns are brought to an end
Disease activity flares and pain flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae
© 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.Background: RA flares are common and disabling. They are described in terms of worsening inflammation but pain and inflammation are often discordant. To inform treatment decisions, we investigated whether inflammatory and pain flares are discrete entities. Methods: People from the Early RA Network (ERAN) cohort were assessed annually up to 11 years after presentation (n = 719, 3703 person-years of follow up). Flare events were defined in 2 different ways that were analysed in parallel; DAS28 or Pain Flares. DAS28 Flares satisfied OMERACT flare criteria of increases in DAS28 since the previous assessment (≥1.2 points if active RA or ≥ 0.6 points if inactive RA). A ≥ 4.8-point worsening of SF36-Bodily Pain score defined Pain Flares. The first documented episode of each of DAS28 and Pain Flare in each person was analysed. Subgroups within DAS28 and Pain Flares were determined using Latent Class Analysis. Clinical course was compared between flare subgroups. Results: DAS28 (45%) and Pain Flares (52%) were each common but usually discordant, with 60% of participants in DAS28 Flare not concurrently in Pain Flare, and 64% of those in Pain Flare not concurrently in DAS28 Flare. Three discrete DAS28 Flare subgroups were identified. One was characterised by increases in tender/swollen joint counts (14.4%), a second by increases in symptoms (13.1%), and a third displayed lower flare severity (72.5%). Two discrete Pain Flare subgroups were identified. One occurred following low disease activity and symptoms (88.6%), and the other occurred on the background of ongoing active disease and pain (11.4%). Despite the observed differences between DAS28 and Pain Flares, each was associated with increased disability which persisted beyond the flare episode. Conclusion: Flares are both common and heterogeneous in people with RA. Furthermore our findings indicate that for some patients there is a discordance between inflammation and pain in flare events. This discrete flare subgroups might reflect different underlying inflammation and pain mechanisms. Treatments addressing different mechanisms might be required to reduce persistent disability after DAS28 and Pain Flares.Peer reviewedFinal Published versio
Dedicated to the Cause: The Role of Identity in Initiating, Sustaining and Diminishing Violent Extremism.
The threat of terrorism and rise of extremist movements across the globe pose some of the greatest challenges the world currently faces. While there have been serious conceptual and methodological problems within the psychological study of terrorism, the nascent field has advanced, and the evidence, theories and models have developed in their sophistication. The current article explores the role of social or collective identity in instigating, propagating and diminishing engagement in violent extremism. Specifically examining how when a fundamental need to belong is challenged through threats and uncertainty this can lead to the people joining entitative groups which can fuse personal and social identities. These identities can be further amplified through ingroup and outgroup processes leading to involvement in violent extremism. The paper also explores how identity can mediate the stress of this extremist lifestyle and sustain engagement in violence. In order to illustrate these processes, the article draws on interviews with Northern Irish paramilitaries. Finally, the paper explores the role of identity in moderating violent extremism, and provides suggestions of approaches to promote desistence from violent extremism
AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury.
Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms. Peripheral nociceptive stimuli induce maladaptive synaptic plasticity in dorsal horn sensory systems through AMPA receptor (AMPAR) phosphorylation and trafficking to synapses. Here we test whether ventral horn motor neurons in rats demonstrate similar experience-dependent maladaptive plasticity below a complete SCI in vivo. Quantitative biochemistry demonstrated that intermittent nociceptive stimulation (INS) rapidly and selectively increases AMPAR subunit GluA1 serine 831 phosphorylation and localization to synapses in the injured spinal cord, while reducing synaptic GluA2. These changes predict motor dysfunction in the absence of cell death signaling, suggesting an opportunity for therapeutic reversal. Automated confocal time-course analysis of lumbar ventral horn motor neurons confirmed a time-dependent increase in synaptic GluA1 with concurrent decrease in synaptic GluA2. Optical fractionation of neuronal plasma membranes revealed GluA2 removal from extrasynaptic sites on motor neurons early after INS followed by removal from synapses 2 h later. As GluA2-lacking AMPARs are canonical calcium-permeable AMPARs (CP-AMPARs), their stimulus- and time-dependent insertion provides a therapeutic target for limiting calcium-dependent dynamic maladaptive plasticity after SCI. Confirming this, a selective CP-AMPAR antagonist protected against INS-induced maladaptive spinal plasticity, restoring adaptive motor responses on a sensorimotor spinal training task. These findings highlight the critical involvement of AMPARs in experience-dependent spinal cord plasticity after injury and provide a pharmacologically targetable synaptic mechanism by which early postinjury experience shapes motor plasticity
Exploring the Impact of Efficacy Messages on Cessation-Related Outcomes Using Ecological Momentary Assessment
Introduction:Observational studies indicate that cigarette package inserts with efficacy messages about the benefits of quitting (i.e. response efficacy) and recommendations for successful cessation increase smokers’ self-efficacy to quit and promote sustained cessation. However, the effects of inserts with such efficacy messages have not been studied using experimental designs. This study used ecological momentary assessment (EMA) to assess smokers’ responses to efficacy inserts.Material and Methods:In a randomized case-crossover study among smokers from the United States (n=23), participants received a one-week supply of cigarettes with efficacy inserts and a one-week supply without any inserts, and were randomized to use the packs with inserts on either the first or second week of the study. For 14 consecutive days, participants used a smartphone to answer brief surveys on cessation-related variables during smoking sessions and at the beginning of each day. Multilevel mixed-effects linear and logistic regression models compared responses during the insert period to those of the non-insert period.Results:The insert period was associated with greater desire to quit (b=0.21, p=0.012), motivation to quit (b=0.18, p=0.001), self-efficacy to cut down (b=0.26, p\u3c0.001) and to quit (b=0.28, p\u3c0.000), and response efficacy/ perceived benefits of quitting (b=0.13, p=0.012). Insert exposure was not significantly associated with forgoing cigarettes (OR=1.9, p=0.2).Conclusions:Results from this EMA study suggest that inserts with efficacy messages may promote determinants of smoking cessation. This is consistent with observational research in Canada, which is the only country to use inserts with efficacy messages as well as pictorial warnings about smoking risks on the outside of packs. Future studies should assess the extent to which efficacy inserts can not only be used to communicate health information to smokers but also work in synergy with pictorial warnings
Dynamical Friction in dE Globular Cluster Systems
The dynamical friction timescale for globular clusters to sink to the center
of a dwarf elliptical galaxy (dE) is significantly less than a Hubble time if
the halos have King-model or isothermal profiles and the globular clusters
formed with the same radial density profile as the underlying stellar
population. We examine the summed radial distribution of the entire globular
cluster systems and the bright globular cluster candidates in 51 Virgo and
Fornax Cluster dEs for evidence of dynamical friction processes. We find that
the summed distribution of the entire globular cluster population closely
follows the exponential profile of the underlying stellar population. However,
there is a deficit of bright clusters within the central regions of dEs
(excluding the nuclei), perhaps due to the orbital decay of these massive
clusters into the dE cores. We also predict the magnitude of each dE's nucleus
assuming the nuclei form via dynamical friction. The observed trend of
decreasing nuclear luminosity with decreasing dE luminosity is much stronger
than predicted if the nuclei formed via simple dynamical friction processes. We
find that the bright dE nuclei could have been formed from the merger of
orbitally decayed massive clusters, but the faint nuclei are several magnitudes
fainter than expected. These faint nuclei are found primarily in M_V > -14 dEs
which have high globular cluster specific frequencies and extended globular
cluster systems. In these galaxies, supernovae-driven winds, high central dark
matter densities, extended dark matter halos, the formation of new star
clusters, or tidal interactions may act to prevent dynamical friction from
collapsing the entire globular cluster population into a single bright nucleus.Comment: 15 pages, 2 tables, 7 figures; to appear in the Astrophysical
Journal, April 20, 200
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