The Ursinus Weekly, April 6, 1942

Earn $21 a day (once a month) as farm worker • Curtain Club announces three cast selections for Mothers\u27 Day plays • Prom will present Criterions as highlight of gala junior weekend • Toy characters to visit Ursinus on Mothers\u27 Day • Three students discuss inter-American affairs at extempore contest • They\u27re on the loose again! Who?: The phys-edders • Nurse to describe opportunities for women in medical field • McClure explains summer session, giving aims of accelerated program • Four Ursinus students participate in IRC model league assembly • Dr. Wentzel addresses final Lenten service • Students to cast ballots on April 14; petitions must be filed by Wednesday • Pre-medders to hear of sneeze bacteriology • Eilts will head German Club; Veuve tells of German schools • Berks County alumni will meet at Reading Country Club Saturday • Bear grapplers tossed by Cheltenham in Hale America exhibition matches • Stevens reveals extensive plans for all golfers • Derr wallops senior girls • Captain Rusty Hoagland paced Jay Vee coeds to booming seasonhttps://digitalcommons.ursinus.edu/weekly/1783/thumbnail.jp

The Ursinus Weekly, April 20, 1942

Former Jap consul to address final forum Wednesday • Becker and Trout elected as student government prexies • Death of Dr. Sibbald comes as blow to entire campus • Pennington head will speak to vespers Sunday • French students to enter cultural olympics at Penn • Debaters attend TKA conclave; conference to be here next year • Mothers\u27 Day festivities will feature crowning of May queen Lenore Berky • Faculty and directors attend rites of Dr. Yost • Greene leads vespers program; includes vocal and instrumental solos • Pirates cop two, replace Phillies in pennant lead • Schmoke hurls Senators to 4-2 win over Yanks • Four minor sports offer instruction to over 100 pupils • Jing considering 150-lb. football for fall program • Men\u27s debate club picks Ditter for new presidenthttps://digitalcommons.ursinus.edu/weekly/1785/thumbnail.jp

The Ursinus Weekly, March 23, 1942

Fister challenges vespers listeners to change views • Pre-medders hear Dr. Eger speak on healing of wounds • Department heads and academic council end seniors\u27 comprehensives • Two proposals will be discussed at meeting of men\u27s student assembly • Beaver economics and pol.-sci. prof is IRC speaker tomorrow night • Prom committee chooses the Criterions to furnish music at spring formal • Y will collect postage stamps and tin foil for Red Cross • God\u27s power is subject of Corum\u27s message to weekly Lenten service • Swartley to head next year\u27s Lantern staff; add four new members • Sollmann calls for total war effort as only means of insuring final victory • Y to sponsor chats in order to stimulate conference enthusiasm • Alumni of Trenton area to organize new local association at banquet • Idea for May pageant came to Betty Urich while a sophomore • Students indicate Miller is favorite dance orchestra • Debaters close season by matching wits with teams in New York area • Compulsory intramural program to begin this Wednesday; dinner hour changed to 5:30 starting Wednesday evening • Snell\u27s squad ends season with 18-18 Chestnut Hill draw • Shreiner and Glenwood play tonight for intramural crown • Associated Press puts captain Al Hutchinson on all league team • Marion Bright placed on all Philadelphia district sextet • Ursinus girls participate in play day Saturday at Temple Universityhttps://digitalcommons.ursinus.edu/weekly/1781/thumbnail.jp

The Ursinus Weekly, April 13, 1942

Asian authority to be speaker at next forum • Navy secretary praises college\u27s V1 cooperation • Faculty and students mourn death of Dr. Calvin D. Yost • Lafayette president will be speaker at commencement • Three hundred dance to rhythms of Criterions at annual junior prom • Students to ballot for major campus officers tomorrow • Scavenging phys-edders comb campus Monday night • Philadelphia and Montco alumni join to honor dean\u27s birthday April 24 • One hundred to vie for scholarships Saturday • Women rush final preparations for shortened May Day pageant • Heibel and Vink review books at meeting of English Club • Co-chairmen announce cancellation of conference • Weekly\u27s roving reporter visits campus den of sin • College chemists urged to make application for government posts • TKA to send four delegates to conference at Albright • Pre-medders hear Dr. Appleton speak on oral hygiene • Nurse describes opportunities for women in medical field • Council on activities requests student groups to reorganize • Stevens fetes varsity matmen • Phils trip Pirates, 10-6, to take over league lead • Men primed for tennis tourney and track meet • Yanks beat Sox and top Browns for fourth win • Hiking and golfing programs hit stride • Girls\u27 intramurals off to fast start • Nat Hogeland, Allie Dougherty end careers in blaze of gloryhttps://digitalcommons.ursinus.edu/weekly/1784/thumbnail.jp

Quantification of brain endocannabinoid levels: methods, interpretations and pitfalls

Endocannabinoids play an important role in a diverse range of neurophysiological processes including neural development, neuroimmune function, synaptic plasticity, pain, reward and affective state. This breadth of influence and evidence for altered endocannabinoid signalling in a variety of neuropathologies has fuelled interest in the accurate quantification of these lipids in brain tissue. Established methods for endocannabinoid quantification primarily employ solvent-based lipid extraction with further sample purification by solid phase extraction. In recent years in vivo microdialysis methods have also been developed for endocannabinoid sampling from the brain interstitial space. However, considerable variability in estimates of endocannabinoid content has led to debate regarding the physiological range of concentrations present in various brain regions. This paper provides a critical review of factors that influence the quantification of brain endocannabinoid content as determined by lipid extraction from bulk tissue and by in vivo microdialysis. A variety of methodological issues are discussed including analytical approaches, endocannabinoid extraction and purification, post-mortem changes in brain endocannabinoid content, cellular reactions to microdialysis probe implantation and caveats related to lipid sampling from the extracellular space. The application of these methods for estimating brain endocannabinoid content and the effects of endocannabinoid clearance inhibition are discussed. The benefits, limitations and pitfalls associated with each approach are emphasized, with an eye toward the appropriate interpretation of data gathered by each method