26 research outputs found
Primary Intracranial Leiomyosarcoma: Report of a Case and Review of the Literature
A 26-year old man presented with a 3-month history of a progressively enlarging palpable parieto-occipital mass. A CT scan indicated the lesion arose from the dura with bony destruction. A stealth assisted craniotomy was performed with the provisional diagnosis of osteoblastic meningioma. Further histopathologic analysis of the intracranial mass was consistent with leiomyosarcoma. Staging evaluation, including CT and PET scans, demonstrated no other sites of disease. Despite complete surgical resection and radiotherapy to the resection site, the disease recurred locally and systematically 5 months later. Primary intracranial mesenchymal tumors are rare and few cases have been previously reported. Outcomes have been universally poor and current therapeutic approaches appear to have only limited benefit
Palliative radiotherapy for superior vena caval obstruction by lung cancer: A major issue about timing and a minor issue about efficacy
Five-year survival after palliative radiotherapy of T4/N3 lung cancer: case series and review of the literature
Palliative radiotherapy for superior vena caval obstruction by lung cancer: A major issue about timing and a minor issue about efficacy
Postoperative radiotherapy for advanced head and neck cancer in patients with cardiac pacemakers
Long-term outcome after gamma knife radiosurgery of advanced jugulotympanic glomus tumour: a case report
Gamma knife radiosurgery for arteriovenous malformations located in eloquent regions of the brain
Background : Stereotactic radiosurgery is an effective treatment
strategy for selected group of patients with cerebral arteriovenous
malformations (AVMs). Aim : The aim of this study was to evaluate the
obliteration rates, complications, and patient outcomes after Gamma
knife radiosurgery for cerebral arteriovenous malformations (AVMs)
located in eloquent regions of the brain with an emphasis on
neurological morbidity. Materials and Methods : Between 2000 and
December 2005, 37 patients with AVMs in eloquent locations (sensory,
motor, speech, visual cortex, basal ganglia, and brain stem) underwent
stereotactic radiosurgery. We retrospectively reviewed the clinical
data of these patients to asses the outcomes. Of the 37 patients, only
two patients had prior embolization. Three underwent prospective staged
volume radiosurgery. Two patients needed redo-radiosurgery for residual
AVM. Mean target volume was 9.1 cc. Three lesions had nidus volume more
than 20 cc. Average marginal dose was 18.75 Gy. The median duration of
follow-up was 23 months (range, 6-60 months). 15 patients had follow-up
of more than 36 months. Results : A total of 15 patients had follow-up
of more than 36 months, thus available for evaluation of angiographic
obliteration rates. Complete angiographic obliteration was documented
in seven patients (46.7%). Four patients experienced hemorrhage during
the latency period. One patient who had subsequent hemorrhage on
follow-up developed worsening of neurological deficit. One patient
developed significant sensory symptoms which resolved after steroids.
No additional clinical deterioration related to treatment was noted in
rest of the patients. Conclusions : AVMs located in eloquent and in
deep locations can be treated safely with stereotactic radiosurgery
with acceptable obliteration rates and minimal morbidity