31 research outputs found

    Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study.

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    Among 2,186 U.S. adults with invasive cancer and laboratory-confirmed SARS-CoV-2 infection, we examined the association of COVID-19 treatments with 30-day all-cause mortality and factors associated with treatment. Logistic regression with multiple adjustments (e.g., comorbidities, cancer status, baseline COVID-19 severity) was performed. Hydroxychloroquine with any other drug was associated with increased mortality versus treatment with any COVID-19 treatment other than hydroxychloroquine or untreated controls; this association was not present with hydroxychloroquine alone. Remdesivir had numerically reduced mortality versus untreated controls that did not reach statistical significance. Baseline COVID-19 severity was strongly associated with receipt of any treatment. Black patients were approximately half as likely to receive remdesivir as white patients. Although observational studies can be limited by potential unmeasured confounding, our findings add to the emerging understanding of patterns of care for patients with cancer and COVID-19 and support evaluation of emerging treatments through inclusive prospective controlled trials. SIGNIFICANCE: Evaluating the potential role of COVID-19 treatments in patients with cancer in a large observational study, there was no statistically significant 30-day all-cause mortality benefit with hydroxychloroquine or high-dose corticosteroids alone or in combination; remdesivir showed potential benefit. Treatment receipt reflects clinical decision-making and suggests disparities in medication access.This article is highlighted in the In This Issue feature, p. 1426

    CDAD-Spektroskopie und -Mikroskopie an Oberflaechen und Adsorbatschichten

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    Available from TIB Hannover: F99B1023+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung und Forschung (BMBF), Bonn (Germany)DEGerman

    Experimental studies of the adsorption of oxygen and nitric oxide at Ni(100)

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    Volkmer M, Nolting K, Fecher GH, Dierks B, Heinzmann U. Experimental studies of the adsorption of oxygen and nitric oxide at Ni(100). Vacuum. 1990;41(1-3):109-111

    Untersuchung der elektronischen Struktur von ferromagnetischen Vielfachschichten Seltener Erden mit Hilfe des magnetischen Dichroismus in der Winkelverteilung von Photoelektronen Abschlussbericht

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    SIGLEAvailable from TIB Hannover: DtF QN1(72,31) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

    Investigation of elemental magnetic moments of CoCrPt films using x-ray magnetic circular dichroism

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    10.4028/3-908451-18-3.191Diffusion and Defect Data Pt.B: Solid State Phenomena111191-194DDBP

    Spin and orbital magnetic moments of FePt thin films

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    10.1143/JJAP.45.2539Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers454 A2539-2541JAPN
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