Immunohistochemical study of breast cancer antigens (part 1)

Survivin has been characterized as a member of the family of inhibitor of apoptosis proteins (lAP). It is a 16.5 kD protein made up of 142 amino acids. Survivin is expressed in the G2/M phase of the cell cycle. It has been previously sho\vn to be expressed in a large number of cancers, and its expression has been associated with the aggression of tumors, or with the poor survival of cancer patients