5,041 research outputs found
Banishing AdS ghosts with a UV cutoff
A recent attempt to make sense of scalars in AdS with "Neumann boundary
conditions" outside of the usual BF-window
led to pathologies including (depending on the precise context) either IR
divergences or the appearance of ghosts. Here we argue that such ghosts may be
banished by imposing a UV cutoff. It is also possible to achieve this goal in
certain UV completions. An example is the above AdS theory with a radial cutoff
supplemented by particular boundary conditions on the cutoff surface. In this
case we explicitly identify a region of parameter space for which the theory is
ghost free. At low energies, this theory may be interpreted as the standard
dual CFT (defined with "Dirichlet" boundary conditions) interacting with an
extra scalar via an irrelevant interaction. We also discuss the relationship to
recent works on holographic fermi surfaces and quantum criticality.Comment: 20 pages, 9 figure
New stability results for Einstein scalar gravity
We consider asymptotically anti de Sitter gravity coupled to a scalar field
with mass slightly above the Breitenlohner-Freedman bound. This theory admits a
large class of consistent boundary conditions characterized by an arbitrary
function . An important open question is to determine which admit stable
ground states. It has previously been shown that the total energy is bounded
from below if is bounded from below and the bulk scalar potential
admits a suitable superpotential. We extend this result and show that the
energy remains bounded even in some cases where can become arbitrarily
negative. As one application, this leads to the possibility that in
gauge/gravity duality, one can add a double trace operator with negative
coefficient to the dual field theory and still have a stable vacuum
Interaction of Liposomal Drug Delivery Systems with Cells and Tissues: Microscopic Studies
Liposomes , as drug carriers, can be administered into the body by several routes e.g. intravenously, intraperitoneally, intramuscularly, intratracheally and topically among others. Radiolabelled markers are suitable to monitor the distribution and elimination of liposomes, but the tissue deposition of intact liposomes, the mode and sites of drug release from the liposomes and liposome-cell interactions cannot be investigated morphologically. Microscopic techniques could provide information regarding the intact state of liposomes and possibly the dynamics of liposomes in tissues provided that they can be identified with certainty in vivo. This is a formidable problem and in spite of several attempts, there is still a lot of work and new ideas needed to overcome this problem.
This paper gives a detailed review of liposome markers used in light and electron microscopy. The use of markers or the technique involved in the identification of liposomes in cells or t issues is discussed.
The feasibility of using colloidal iron, a new electron dense marker, as a marker for intravenously injected liposomes was investigated in mice. Intact multilamellar vesicles containing colloidal iron were identified in the liver, spleen and lung of mice injected with liposomes. The liver and the spleen are organs for the storage of iron containing proteins (ferritin, hemosiderin), therefore studying the disposition of colloidal iron from the liposomes was not possible. However, in organs not containing iron, e.g. lung, the presence of colloidal iron can easily be recognized. The colloidal iron marker may be suitable to label liposomes targeted to the brain , heart or certain tumors
Deconstructing holographic liquids
We argue that there exist simple effective field theories describing the
long-distance dynamics of holographic liquids. The degrees of freedom
responsible for the transport of charge and energy-momentum are Goldstone
modes. These modes are coupled to a strongly coupled infrared sector through
emergent gauge and gravitational fields. The IR degrees of freedom are
described holographically by the near-horizon part of the metric, while the
Goldstone bosons are described by a field-theoretical Lagrangian. In the cases
where the holographic dual involves a black hole, this picture allows for a
direct connection between the holographic prescription where currents live on
the boundary, and the membrane paradigm where currents live on the horizon. The
zero-temperature sound mode in the D3-D7 system is also re-analyzed and
re-interpreted within this formalism.Comment: 21 pages, 2 figure
RG flow of transport quantities
The RG flow equation of various transport quantities are studied in arbitrary
spacetime dimensions, in the fixed as well as fluctuating background geometry
both for the Maxwellian and DBI type of actions. The regularity condition on
the flow equation of the conductivity at the horizon for the DBI action
reproduces naturally the leading order result of {\it Hartnoll et al.}, [{\it
JHEP}, {\bf 04}, 120 (2010)]. Motivated by the result of {\it van der Marel et
al.}, [{\it science}, {\bf 425}, 271 (2003], we studied, analytically, the
conductivity versus frequency plane by dividing it into three distinct parts:
and . In order to compare, we choose 3+1
dimensional bulk spacetime for the computation of the conductivity. In the
range, the conductivity does not show up the Drude like form in any
spacetime dimensions. In the range and staying away from the
horizon, for the DBI action with unit dynamical exponent, non-zero magnetic
field and charge density, the conductivity goes as , whereas the
phase of the conductivity, goes as,
and . There exists a universal
quantity at the horizon that is the phase angle of conductivity, which either
vanishes or an integral multiple of . Furthermore, we calculate the
temperature dependence to the thermoelectric and the thermal conductivity at
the horizon. The charge diffusion constant for the DBI action is studied.Comment: 1+68 pages, 12 figures and 4 appendices; V2: The charge diffusion
constant is calculated for arbitrary spacetime dimensions and related
references added; v3: Connection with the RG flow of 1010.4036 is made; v4:
Several corrections, typos fixed and a ref. adde
Holographic Wilsonian flows and emergent fermions in extremal charged black holes
We study holographic Wilsonian RG in a general class of asymptotically AdS
backgrounds with a U(1) gauge field. We consider free charged Dirac fermions in
such a background, and integrate them up to an intermediate radial distance,
yielding an equivalent low energy dual field theory. The new ingredient,
compared to scalars, involves a `generalized' basis of coherent states which
labels a particular half of the fermion components as coordinates or momenta,
depending on the choice of quantization (standard or alternative). We apply
this technology to explicitly compute RG flows of charged fermionic operators
and their composites (double trace operators) in field theories dual to (a)
pure AdS and (b) extremal charged black hole geometries. The flow diagrams and
fixed points are determined explicitly. In the case of the extremal black hole,
the RG flows connect two fixed points at the UV AdS boundary to two fixed
points at the IR AdS_2 region. The double trace flow is shown, both numerically
and analytically, to develop a pole singularity in the AdS_2 region at low
frequency and near the Fermi momentum, which can be traced to the appearance of
massless fermion modes on the low energy cut-off surface. The low energy field
theory action we derive exactly agrees with the semi-holographic action
proposed by Faulkner and Polchinski in arXiv:1001.5049 [hep-th]. In terms of
field theory, the holographic version of Wilsonian RG leads to a quantum theory
with random sources. In the extremal black hole background the random sources
become `light' in the AdS_2 region near the Fermi surface and emerge as new
dynamical degrees of freedom.Comment: 37 pages (including 8 pages of appendix), 10 figures and 2 table
Magnetic Field Induced Quantum Criticality via new Asymptotically AdS_5 Solutions
Using analytical methods, we derive and extend previously obtained numerical
results on the low temperature properties of holographic duals to
four-dimensional gauge theories at finite density in a nonzero magnetic field.
We find a new asymptotically AdS_5 solution representing the system at zero
temperature. This solution has vanishing entropy density, and the charge
density in the bulk is carried entirely by fluxes. The dimensionless magnetic
field to charge density ratio for these solutions is bounded from below, with a
quantum critical point appearing at the lower bound. Using matched asymptotic
expansions, we extract the low temperature thermodynamics of the system. Above
the critical magnetic field, the low temperature entropy density takes a simple
form, linear in the temperature, and with a specific heat coefficient diverging
at the critical point. At the critical magnetic field, we derive the scaling
law s ~ T^{1/3} inferred previously from numerical analysis. We also compute
the full scaling function describing the region near the critical point, and
identify the dynamical critical exponent: z=3.
These solutions are expected to holographically represent boundary theories
in which strongly interacting fermions are filling up a Fermi sea. They are
fully top-down constructions in which both the bulk and boundary theories have
well known embeddings in string theory.Comment: 50 page
Mixed RG Flows and Hydrodynamics at Finite Holographic Screen
We consider quark-gluon plasma with chemical potential and study
renormalization group flows of transport coefficients in the framework of
gauge/gravity duality. We first study them using the flow equations and compare
the results with hydrodynamic results by calculating the Green functions on the
arbitrary slice. Two results match exactly. Transport coefficients at arbitrary
scale is ontained by calculating hydrodynamics Green functions. When either
momentum or charge vanishes, transport coefficients decouple from each other.Comment: 22 pages, 6 figure
Anomalous Zero Sound
We show that the anomalous term in the current, recently suggested by Son and
Yamamoto, modifies the structure of the zero sound mode in the Fermi liquid in
a magnetic field.Comment: 14 pages, 2 figure
Holographic fermions in charged Gauss-Bonnet black hole
We study the properties of the Green's functions of the fermions in charged
Gauss-Bonnet black hole. What we want to do is to investigate how the presence
of Gauss-Bonnet coupling constant affects the dispersion relation,
which is a characteristic of Fermi or non-Fermi liquid, as well as what
properties such a system has, for instance, the Particle-hole (a)symmetry. One
important result of this research is that we find for , the behavior of
this system is different from that of the Landau Fermi liquid and so the system
can be candidates for holographic dual of generalized non-Fermi liquids. More
importantly, the behavior of this system increasingly similar to that of the
Landau Fermi liquid when is approaching its lower bound. Also we find
that this system possesses the Particle-hole asymmetry when , another
important characteristic of this system. In addition, we also investigate
briefly the cases of the charge dependence.Comment: 22 pages, 6 figures; version published in JHE
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