Using Organization Theory to Explore the Changing Role of Medical Libraries

This historical research review uses organization theory to describe and interpret the evolution of American hospitals, medical libraries, and the role of the professional librarian. Various organization theories are applied to explain changes in hospitals and medical libraries over time. The interaction between the organization and the environment as described in organization theory shaped the emergence of today\u27s information services. For readers unfamiliar with health sciences libraries, the study will provide a glimpse into the social forces that framed the development of this type of special library

Do Health Sciences Libraries and Librarians Have an Impact on the Cost of Health Care and Research? A Systematic Review

Objectives: The team worked on a systematic review to answer the question: Do health sciences libraries and librarians have any measurable (statistically significant) positive impacts on consumer health, the outcomes of medical care, the productivity of biomedical researchers, and the knowledge obtained by graduates of biomedical and health sciences training programs, and at what total cost? Methods: The team used a Google site to collaborate on the review. A spreadsheet was used to brainstorm keywords and list suggestions for subject headings. Databases searched included: PubMed/MEDLINE, CINAHL, ERIC, LISTA, Cochrane Library, and Web of Science. The team searched grey literature and conducted a citation search, and hand searched bibliographies and journal contents. Although the team preferred to use only research reports, the main inclusion criteria was articles that mentioned the cost factor of the library or librarian impact

A multitiered analysis platform for genome sequencing: Design and initial findings of the Australian Genomics Cardiovascular Disorders Flagship

Purpose: The Australian Genomics Cardiovascular Disorders Flagship was a national multidisciplinary collaboration. It aimed to investigate the feasibility of genome sequencing (GS) and functional genomics to resolve variants of uncertain significance (VUS) in the clinical management of patients and families with cardiomyopathies, primary arrhythmias, and congenital heart disease (CHD). Methods: Between April 2019 and December 2021, 600 probands meeting cardiovascular disorder criteria from 17 cardiology and genetics clinics across Australia were enrolled in the Flagship and underwent GS. The Flagship adopted a tiered approach to GS analysis. Tier 1 analysis assessed genes with established clinical validity for each cardiovascular condition. Tier 2 analysis assessed lesser-evidenced research-based genes. Tier 3 analysis assessed the functional impact of VUS that remained after tier 1 and tier 2 analysis. Results: Overall, a pathogenic or likely pathogenic variant was identified in 41% of participants with a cardiomyopathy, 40% with an arrhythmia syndrome, and 15% with a familial CHD/CHD+Extra Cardiac Anomalies. A VUS outcome ranged from 13% for arrhythmias to 34% for CHD/CHD+Extra Cardiac Anomalies participants. Tier 2 research analysis identified a likely pathogenic/pathogenic variant for a further 15 participants and a VUS for an additional 15 participants. Conclusion: The Flagship successfully facilitated a model of care that harnesses clinical GS and functional genomics for the resolution of VUS in the clinical setting. This valuable data set can be used to inform clinical practice and facilitate research into the future