The Relationship between the UniProt Knowledgebase (UniProtKB) and the IntAct Molecular Interaction Databases

IntAct provides a freely available, open source database system and analysis tools for protein interaction data. All interactions are derived from literature curation or direct user submission and all experimental information relating to binary protein-protein
interactions is entered into the IntAct database by curators, via a web-based editor. Interaction information is added to the SUBUNIT comment and the RP line of the relevant publication within the UniProtKB entry. There may be a single INTERACTION comment present within a UniProtKB entry, which conveys information relevant to binary protein-protein interactions. This is automatically derived from the IntAct database and is updated on a triweekly basis. Interactions can be derived by any appropriate experimental method but must be confirmed by a second interaction if resulting from a single yeast2hybrid experiment. For large-scale experiments, interactions are considered if a high confidence score is assigned by the authors. The INTERACTION line contains a direct link to IntAct that provides detailed information for the experimental support. These lines are not changed manually and any discrepancy is reported to IntAct for updates. There is also a database crossreference line within the UniProtKB entry i.e.: DR IntAct _UniProtKB AC, which directs the user to additional interaction data for that molecule. 
UniProt is supported by grants from the National Institutes of Health, European Commission, Swiss Federal Government and PATRIC BRC.
IntAct is funded by the European Commission under FELICS, contract number 021902 (RII3) within the Research Infrastructure Action of the FP6 "Structuring the European Research Area" Programme

Poor fish farmers' accessibility to credits: A review

Fisheries sector contributes about 5.3% to GDP and about 6% of the export earnings of Bangladesh. There are about 4.1 million ha of inland water bodies in Bangladesh. However, over last two decades the catch from inland capture fishery has decreased due to filling of wet lands and other anthropogenic reasons. Accordingly, the production of inland fish has decreased not only for the decrease of water bodies but also due to irrational catch of fish fries, brood fishes and use of current nets for fishing. Significant responses from the fisheries entrepreneurs have not been received for the small loan scheme of the Bangladesh Bank. The bank could not disburse more than Tk. 500 million under the scheme. The total revolving credit under the scheme was Tk. 1,000 million with the assistance from the World Bank. The business houses having fixed assets of value not more than Tk. 10 million will be eligible to borrow from this fund. About Tk. 0.2-5.0 million can be borrowed as term loan and working capital from Bangladesh Bank through commercial banks. The loan was given to the commercial banks at 5% interest (bank rate) and the commercial banks shall also bridge finance to the entrepreneurs at a lower rate of interest. Working capital time limit is for a maximum of 1 year with half yearly rest, mid-term loan maximum of 3 years in 5 installments and with 6 months grace period and long-term loan maximum of 5 years in 9 installments with 6 months grace period

Dynamic Behavior of Bed Material around Bridge Pier under Abrupt Change of Water Pressure

Major failure of structures usually occurs during flood flows due to scourin, sinking and sliding. These types of failure are considered to be in close relation to the dynamic behavior of bed material around the structures. Failure of bridges due to the phenomenon of scouring around piers is a common, natural problem of river hydraulics. Experiments were carried out to investigate the characteristics of pore water pressure and effective stresses in the bed material around a circular bridge pier under abrupt change of water pressure. A laboratory model was used to clarify the effect of the variation of water pressure to determine the mechanism of the collapse of circular bridge pier during flood or storm waves. The experimental results showed that the bed material under suddeen change in drop of water pressure near the pier was weakenend by an increase in excess pore pressure, followed by a considerable quick removal of bed material

Comparing the Overhead of Topological and Concatenated Quantum Error Correction

This work compares the overhead of quantum error correction with concatenated and topological quantum error-correcting codes. To perform a numerical analysis, we use the Quantum Resource Estimator Toolbox (QuRE) that we recently developed. We use QuRE to estimate the number of qubits, quantum gates, and amount of time needed to factor a 1024-bit number on several candidate quantum technologies that differ in their clock speed and reliability. We make several interesting observations. First, topological quantum error correction requires fewer resources when physical gate error rates are high, white concatenated codes have smaller overhead for physical gate error rates below approximately 10E-7. Consequently, we show that different error-correcting codes should be chosen for two of the studied physical quantum technologies - ion traps and superconducting qubits. Second, we observe that the composition of the elementary gate types occurring in a typical logical circuit, a fault-tolerant circuit protected by the surface code, and a fault-tolerant circuit protected by a concatenated code all differ. This also suggests that choosing the most appropriate error correction technique depends on the ability of the future technology to perform specific gates efficiently

Spotted wing drosophila: distribution of populations over time in wild and crop hosts

Spotted wing drosophila (SWD) was first confirmed in NY at some eastern Long Island farms in 2011. Fruit flies typically attack rotting fruits; SWD, however, feeds in intact fruits. Soft-skinned fruits such as berries are at greatest risk; some stone fruits are also reported among the preferred hosts. Season-long SWD monitoring and fruit damage assessments were done in cultivated crops and in wild fruits growing nearby. A total of 31 apple cider vinegar-baited translucent delicatessen cup monitoring traps were placed in raspberry, peach, blueberry, grape, and apple farms and in adjacent forest areas. The first sustained SWD capture on Long Island occurred on June 9, 2012 at 1320 DD (50oF base temperature). At least two peak SWD activity periods were observed on Long Island: the 1st around September 18 at 2313 DD and the 2nd around October 23 at 3073 DD. The proportion of male:female in trapped populations was observed to be around 50:50. Late-season (September – October) SWD populations appeared to be higher in forest than cultivated areas. Approximately 17 types of cultivated and wild fruits were checked for the presence of SWD eggs or larvae. Pokeweed berries are the most preferred wild host of SWD. Among the other possible wild hosts checked- autumn olive, bittersweet nightshade, European yew berries are the newly detected hosts of SWD grown near cultivated areas. Raspberries and blackberries were most heavily infested by SWD, averaging 73.5% and 77.0% respectively in 2012. Blueberries were less affected (6%) possibly because the local blueberry season typically ends by late July to early August after which SWD populations sharply increased. Very few SWD adults emerged from grape samples and SWD egg-laying in grapes was minimal and only the late-season 'Merlot' and 'Cabernet' varieties were affected. It appears grapes are not a favored host and may not need preventive treatment. Late-season caneberries appear highly susceptible to infestation and most likely require preventive insecticide treatments but growers have little information on specific timing of applications. Information developed from this study advances our understanding of the seasonal abundance, peak appearance, host utilization, and overwintering emergence patterns of SWD. Further research on hosts, overwintering sites, population assessment, baits and control techniques are necessary to help growers contend with this new invasive pest