6 research outputs found

    From the sierra to the lowlands: new data on the settlement of the Barbanza Peninsula from Prehistoric to Medieval times

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    Procédese á revisión dos traballos de prospección previa na serra do Barbanza e ampliados aos montes de Macenda e Bealo na procura de asentamentos gandeiros/pastorís, no curso deses traballos localizáronse ademáis un interesante xacemento de cronoloxía calcolítca e un castro inédito. Asemade, dáse conta dos resultados das intervencións en dous xacementos, un de carácter gandeiro que presenta un palimpsesto estrutural e cronolóxico (Río Barbanza), e outro relacionado con sistemas de control territorial (Outeiro da Torre).We review the survey works carried through in the district of Barbanza, now extended to the parishes of Macenda and Bealo in search of livestock / pastoral settlements. In the course of these explorations a Copper Age site was discovered and, nearby, a previously unknown hillfort. An account is given of the results of the digging in two sites; one related to husbandry tasks, that presents a structural and chronological palimpsest (Rio Barbanza); and another more, related to territorial control systems (Outeiro da Torre)

    Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

    A definición arqueolóxica dunha nova trama parcelaria: os destrais

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    Este traballo céntrase na identificación dun parcelario histórico singular: o dextro, destral ou diestral; un elemento presente na toponimia actual e que se pode rastrexar na documentación histórica galega e estudada tanto por historiadores medievalistas como por xuristas, pero que pasou inadvertido para os estudos arqueolóxicos. Rastréxase a orixe histórica do destral, xustifícase o seu análise como elemento de estudo e se procede a súa identificación describindo a metodoloxía empregada, para finalmente delimitar fisicamente nove casos de estudo e comparalos resultados métricos coa información procedente das fontes históricas

    Ocupacións domésticas na serra do Barbanza: resultados preliminares

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    A Serra do Barbanza espertou especial interese entre os investigadores galegos para o estudo do fenómeno tumular dada a gran concentración que presenta, contrastando coa total ausencia de xacementos domésticos; pero nos últimos anos están aflorando un conxunto de xacementos arqueolóxicos extraordinarios, tanto pola densidade dos mesmos como polas súas características, que modifica substancialmente a imaxe que se tiña da Serra como unha área marxinal cara un espazo intensamente ocupado e explotado. A escavación de varios destes novos xacementos permitiron constatar a presenza de hábitats domésticos e de ocupacións reiteradas no tempo dende o Bronce Final ou Idade do Ferro ata a Alta Idade Media

    From the sierra to the lowlands: new data on the settlement of the Barbanza Peninsula from Prehistoric to Medieval times

    No full text
    Procédese á revisión dos traballos de prospección previa na serra do Barbanza e ampliados aos montes de Macenda e Bealo na procura de asentamentos gandeiros/pastorís, no curso deses traballos localizáronse ademáis un interesante xacemento de cronoloxía calcolítca e un castro inédito. Asemade, dáse conta dos resultados das intervencións en dous xacementos, un de carácter gandeiro que presenta un palimpsesto estrutural e cronolóxico (Río Barbanza), e outro relacionado con sistemas de control territorial (Outeiro da Torre).We review the survey works carried through in the district of Barbanza, now extended to the pa-rishes of Macenda and Bealo in search of livestock / pastoral settlements. In the course of these explorations a Copper Age site was discovered and, nearby, a previously unknown hillfort. An ac-count is given of the results of the digging in two sites; one related to husbandry tasks, that presents a structural and chronological palimpsest (Rio Barbanza); and another more, related to territorial control systems (Outeiro da Torre)

    Do planalto ás terras baixas: novas achegas á ocupación da península do Barbanza dende a Prehistoria ata o Medievo

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    We review the survey works carried through in the district of Barbanza, now extended to the pa-rishes of Macenda and Bealo in search of livestock / pastoral settlements. In the course of these explorations a Copper Age site was discovered and, nearby, a previously unknown hillfort. An ac-count is given of the results of the digging in two sites; one related to husbandry tasks, that presents a structural and chronological palimpsest (Rio Barbanza); and another more, related to territorial control systems (Outeiro da Torre).Procédese á revisión dos traballos de prospección previa na serra do Barbanza e ampliados aos montes de Macenda e Bealo na procura de asentamentos gandeiros/pastorís, no curso deses traballos localizáronse ademáis un interesante xacemento de cronoloxía calcolítca e un castro inédito. Asemade, dáse conta dos resultados das intervencións en dous xacementos, un de carácter gandeiro que presenta un palimpsesto estrutural e cronolóxico (Río Barbanza), e outro relacionado con sistemas de control territorial (Outeiro da Torre)
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