Quantum effects and superquintessence in the new age of precision cosmology

Recent observations of Type Ia supernova at high redshifts establish that the dark energy component of the universe has (a probably constant) ratio between pressure and energy density $w=p/\rho=-1.02(^{+0.13}_{-0.19})$. The conventional quintessence models for dark energy are restricted to the range $-1\le w < 0$, with the cosmological constant corresponding to $w=-1$. Conformally coupled quintessence models are the simplest ones compatible with the marginally allowed superaccelerated regime ($w<-1$). However, they are known to be plagued with anisotropic singularities. We argue here that the extension of the classical approach to the semiclassical one, with the inclusion of quantum counterterms necessary to ensure the renormalization, can eliminate the anisotropic singularities preserving the isotropic behavior of conformally coupled superquintessence models. Hence, besides of having other interesting properties, they are consistent candidates to describe the superaccelerated phases of the universe compatible with the present experimental data.Comment: 7 pages. Essay selected for "Honorable Mention" in the 2004 Awards for Essays on Gravitation, Gravity Research Foundatio

Randomized, Double-Blind Comparative Trial of Subunit and Virosomal Influenza Vaccines for Immunocompromised Patients

Background.. To our knowledge, no study to date has compared the effects of a subunit influenza vaccine with those of a virosomal influenza vaccine on immunocompromised patients. Methods.. A prospective, double-blind, randomized study was conducted to compare the immunogenicity and reactogenicity of subunit and virosomal influenza vaccines for adult patients who had an immunosuppressive disease or who were immunocompromised as a result of treatment. Results.. There were 304 patients enrolled in our study: 131 with human immunodeficiency virus (HIV) infection, 47 with a chronic rheumatologic disease, 74 who underwent a renal transplant, 47 who received long-term hemodialysis, and 5 who had some other nephrologic disease. There were 151 patients who received the subunit vaccine and 153 patients who received the virosomal vaccine. A slightly higher percentage of patients from the subunit vaccine group were protected against all 3 influenza vaccine strains after being vaccinated, compared with patients from the virosomal vaccine group (41% vs. 30% of patients; P=.03). Among HIV-infected patients, the level of HIV RNA, but not the CD4 cell count, was an independent predictor of vaccine response. Among renal transplant patients, treatment with mycophenolate significantly reduced the immune response to vaccination. The 2 vaccines were comparable with regard to the frequency and severity of local and systemic reactions within 7 days after vaccination. Disease-specific scores for the activity of rheumatologic diseases did not indicate flare-ups 4-6 weeks after vaccination. Conclusions.. For immunosuppressed patients, the subunit vaccine was slightly more immunogenic than the virosomal vaccine. The 2 vaccines were comparable with regard to reactogenicity. Vaccine response decreased with increasing degree of immune suppression. Among HIV-infected patients, the viral load, rather than the CD4 cell count, predicted the protective immune response to the vaccine. Clinical trials registration.. NCT0078338

Model-Independent Comparisons of Pulsar Timings to Scalar-Tensor Gravity

Observations of pulsar timing provide strong constraints on scalar-tensor theories of gravity, but these constraints are traditionally quoted as limits on the microscopic parameters (like the Brans-Dicke coupling, for example) that govern the strength of scalar-matter couplings at the particle level in particular models. Here we present fits to timing data for several pulsars directly in terms of the phenomenological couplings (masses, scalar charges, moment of inertia sensitivities and so on) of the stars involved, rather than to the more microscopic parameters of a specific model. For instance, for the double pulsar PSR J0737-3039A/B we find at the 68% confidence level that the masses are bounded by 1.28 < m_A/m_sun < 1.34 and 1.19 < m_B/m_sun < 1.25, while the scalar-charge to mass ratios satisfy |a_A| < 0.21, |a_B| < 0.21 and |a_B - a_A| < 0.002$. These constraints are independent of the details of the scalar tensor model involved, and of assumptions about the stellar equations of state. Our fits can be used to constrain a broad class of scalar tensor theories by computing the fit quantities as functions of the microscopic parameters in any particular model. For the Brans-Dicke and quasi-Brans-Dicke models, the constraints obtained in this manner are consistent with those quoted in the literature.Comment: 19 pages, 7 figure

Mapping the CMB Sky: The BOOMERANG experiment

We describe the BOOMERanG experiment, a stratospheric balloon telescope intended to measure the Cosmic Microwave Background anisotropy at angular scales between a few degrees and ten arcminutes. The experiment has been optimized for a long duration (7 to 14 days) flight circumnavigating Antarctica at the end of 1998. A test flight was performed on Aug.30, 1997 in Texas. The level of performance achieved in the test flight was satisfactory and compatible with the requirements for the long duration flight.Comment: 11 pages, 6 figure

First Estimations of Cosmological Parameters From BOOMERANG

The anisotropy of the cosmic microwave background radiation contains information about the contents and history of the universe. We report new limits on cosmological parameters derived from the angular power spectrum measured in the first Antarctic flight of the BOOMERANG experiment. Within the framework of inflation-motivated adiabatic cold dark matter models, and using only weakly restrictive prior probabilites on the age of the universe and the Hubble expansion parameter $h$, we find that the curvature is consistent with flat and that the primordial fluctuation spectrum is consistent with scale invariant, in agreement with the basic inflation paradigm. We find that the data prefer a baryon density $\Omega_b h^2$ above, though similar to, the estimates from light element abundances and big bang nucleosynthesis. When combined with large scale structure observations, the BOOMERANG data provide clear detections of both dark matter and dark energy contributions to the total energy density $\Omega_{\rm {tot}}$, independent of data from high redshift supernovae.Comment: As submitted to PRD, revised longer version with an additional figur

The BOOMERANG North America Instrument: a balloon-borne bolometric radiometer optimized for measurements of cosmic background radiation anisotropies from 0.3 to 4 degrees

We describe the BOOMERANG North America (BNA) instrument, a balloon-borne bolometric radiometer designed to map the Cosmic Microwave Background (CMB) radiation with 0.3 deg resolution over a significant portion of the sky. This receiver employs new technologies in bolometers, readout electronics, millimeter-wave optics and filters, cryogenics, scan and attitude reconstruction. All these subsystems are described in detail in this paper. The system has been fully calibrated in flight using a variety of techniques which are described and compared. It has been able to obtain a measurement of the first peak in the CMB angular power spectrum in a single balloon flight, few hours long, and was a prototype of the BOOMERANG Long Duration Balloon (BLDB) experiment.Comment: 40 pages, 22 figures, submitted to Ap

Noise Properties of the BOOMERANG Instrument

In this paper we report a short description of the BOOMERANG experiment explaining his scientific goal and the technologies implied. We concentrate then on the analysis of the noise properties discussing in particular the scan synchronous noise. Finally we present the calibration technique and the sensitivity of all the channels

Images of the Early Universe from the BOOMERanG experiment

The CMB is the fundamental tool to study the properties of the early universe and of the universe at large scales. In the framework of the Hot Big Bang model, when we look to the CMB we look back in time to the end of the plasma era, at a redshift ~ 1000, when the universe was ~ 50000 times younger, ~ 1000 times hotter and ~ 10^9 times denser than today. The image of the CMB can be used to study the physical processes there, to infer what happened before, and also to study the background geometry of our Universe