259 research outputs found

    Relativistic Effects on the Appearance of a Clothed Black Hole

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    For an accretion disk around a black hole, the strong relativistic effects affect every aspect of the radiation from the disk, including its spectrum, light-curve, and image. This work investigates in detail how the images of a thin disk around a black hole will be distorted, and what the observer will see from different viewing angles and in different energy bands.Comment: 4 pages, 5 figures. Based on the poster presented at the Sixth Pacific Rim Conference on Stellar Astrophysics (Xi'an, China, July 11-17, 2002). Color versions of figures are given separatel

    The relativistic Iron K-alpha line from an accretion disc onto a static non-baryonic compact object

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    This paper continues the study of the properties of an accretion disc rotating around a non-baryonic (assumed super-massive) compact object. This kind of objects, generically known as boson stars, were earlier proposed as a possible alternative scenario to the existence of super-masive black holes in the center of every galaxy. A dilute boson star has also been proposed as a large part of the non-baryonic dark matter, flattening galactic rotational velocities curves. In this contribution, we compute the profile of the emission lines of Iron; its shape has been for long known as a useful diagnosis of the space-time geometry. We compare with the case of a Schwarzschild black hole, concluding that the differences are observationally distinguishable.Comment: 14 pages, 7 figure

    State of the art in bile analysis in forensic toxicology

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    AbstractIn forensic toxicology, alternative matrices to blood are useful in case of limited, unavailable or unusable blood sample, suspected postmortem redistribution or long drug intake-to-sampling interval. The present article provides an update on the state of knowledge for the use of bile in forensic toxicology, through a review of the Medline literature from 1970 to May 2015. Bile physiology and technical aspects of analysis (sampling, storage, sample preparation and analytical methods) are reported, to highlight specificities and consequences from an analytical and interpretative point of view. A table summarizes cause of death and quantification in bile and blood of 133 compounds from more than 200 case reports, providing a useful tool for forensic physicians and toxicologists involved in interpreting bile analysis. Qualitative and quantitative interpretation is discussed. As bile/blood concentration ratios are high for numerous molecules or metabolites, bile is a matrix of choice for screening when blood concentrations are low or non-detectable: e.g., cases of weak exposure or long intake-to-death interval. Quantitative applications have been little investigated, but small molecules with low bile/blood concentration ratios seem to be good candidates for quantitative bile-based interpretation. Further experimental data on the mechanism and properties of biliary extraction of xenobiotics of forensic interest are required to improve quantitative interpretation

    Beam profile reflectometry: a new technique for thin film measurements

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    In the manufacture of semiconductor devices, it is of critical importance to know the thickness and material properties of various dielectric and semiconducting thin films. Although there are many techniques for measuring these films, the most commonly used are reflection spectrophotometry [1,2] and ellipsometry [3]. In the former method, the normal- incidence reflectivity is measured as a function of wavelength. The shape of the reflectivity spectrum is then analyzed using the Fresnel equations to determine the thickness of the film. In some cases, the refractive index can also be determined provided that the dispersion of the optical constants are well known. The latter method consists of reflecting a beam of known polarization off the sample surface at an oblique angle. The film thickness, and in some cases the refractive index, can be determined from the change in polarization experienced upon reflection

    Low-Temperature Photothermal Measurements of High-TCSuperconductors

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    Thermal conductivity provides important information on the scattering mechanisms in a material. In anisotropic materials, such as the high-temperature superconductors, the thermal conductivity depends on the anisotropy of both the charge carriers and the lattice contribution. The conductivity also depends intimately on the nature of the electron-phonon interactions which are a major source of the scattering. Since the electron-phonon interaction also plays a critical role in the Bardeen, Cooper, and Schrieffer (BCS) theory of superconductivity, measurements of the thermal conductivity can provide insight into the superconducting mechanism

    Swimming into peptidomimetic chemical space using pepMMsMIMIC

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    pepMMsMIMIC is a novel web-oriented peptidomimetic compound virtual screening tool based on a multi-conformers three-dimensional (3D)-similarity search strategy. Key to the development of pepMMsMIMIC has been the creation of a library of 17 million conformers calculated from 3.9 million commercially available chemicals collected in the MMsINC® database. Using as input the 3D structure of a peptide bound to a protein, pepMMsMIMIC suggests which chemical structures are able to mimic the protein–protein recognition of this natural peptide using both pharmacophore and shape similarity techniques. We hope that the accessibility of pepMMsMIMIC (freely available at http://mms.dsfarm.unipd.it/pepMMsMIMIC) will encourage medicinal chemists to de-peptidize protein–protein recognition processes of biological interest, thus increasing the potential of in silico peptidomimetic compound screening of known small molecules to expedite drug development
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