Modeling Carne PRI supply chain with the *-Chain Platform

Certification of the origin of products and control over the production chain are fundamental activities that can make goods competitive. Therefore, it is of great interest to develop platforms that enable domain experts to build supply chain management systems with easy-to-use systems, providing integration with structures that can guarantee the certification of a certain good. This paper shows how the*-chain framework solves this problem. In particular, we represent the use case: "Pezzata Rossa" - Carne PRI supply chain.*-chain generates the related blockchain-based traceability system. The framework's tools generate a set of solidity smart contracts implementing the system and three web interfaces to interact with them

A Simplified Method to Assess Acceleration Loads on Sailing Yacht Masts.

The behavior of sailing boats in open sea is related not only to their hydrodynamic performances but also to the dynamic loads acting on the hull and rigging. Especially in case of large vessels these loads cannot be neglected and their evaluation could be done just by a careful seakeeping analysis. Particular attention should be devoted to the acceleration loads caused by pitching motions which can create severe problems to mast and rigging, with extreme consequence represented by the mast collapse. As a matter of fact dismasting can be an impressive event, very dangerous for crew and very expensive to be repaired. Apart from the human error, one of the main reason of dismasting is represented by the lack of estimation of loads that could be applied to mast and rigging by the dynamic behavior of the vessel at sea. In addition Classification Societies' Rules are quite poor about this subject and the mast and rigging design is normally in the hands of designers. The aim of this work is to investigate in deep the causes which can cause dismasting and to propose possible actions to avoid it. With this goal in mind a study of the pitching behavior of a number of different sailing yachts has been carried out by the well known HydroStar software: it is a potential flow solver using panel methods and developed by Bureau Veritas. The investigation was aimed at studying the main parameters that drive sailing boat pitching behavior. This could be considered a first step in view of the formulation of a simplified method, able to quickly estimate inertial loads due to waves. Pitching motions in regular waves are calculated and analyzed for a small set of modern sailing yachts hulls. Despite the small size of the database a first simple method to estimate pitch RAO is proposed, based only on the boat length. From the pitch knowledge a very rough and quick formulation to evaluate the longitudinal acceleration in the mast centre of gravity has been carried out. A state-of-the-art process is then used in order to achieve results in irregular sea states and compute time series. Good agreement with some full scale measurements is shown in term of pitching

Real scale measurements of yacht\u2019s mast accelerations

Dismasting is one of the most serious hazards for sailing boats. This event is mainly due to structural defects, poor maintenance or adverse weather conditions. For what the last aspect is concerned, it may be associated to two types of loads: the direct action of the wind on sails and accelerations caused by ship motions. The aim of this paper is to focus on the accelerations induced on the mast by ship motions using seakeeping analysis validated by real scale measurements carried out on two sailing yachts during their transfer trips from South Africa to Italy. After measurements, the recorded data have been analyzed, reordered and related to the weather conditions encountered during the transfer voyage. Then seakeeping calculations have been carried out in order to compare numerical prediction with experimental values. Finally, acceleration values to be considered for preliminary mast scantling, were derived

Simplified analytical method for the evaluation of longitudinal strength of large sailing yachts

Yacht manufactory industries have been faced with two different trends over the last few years: on the one hand, the current economic crisis, which has halted the production of super and mega yachts, and on the other, the increase in the dimensions of both sailing and motor yachts. In the case of sailing yachts, this trend has brought about a consequent increase in rigging proportions. Higher masts and wider sail plans have led to an enormous increase in rigging and sheet loadings. Meanwhile, speed has become an increasingly important focal point in the design process, in order to respond to market requirements; this scenario requires an acceptable compromise between structural requirements due to high rigging loads and structural weight reduction to improve the craft speed and to reduce costs and production times. For these reasons, the global strength of the hull has become a crucial aspect in the design process. Traditionally, only still water and wave bending moment in hogging and sagging conditions have been considered as global loads. For sailing yachts, however, the dock tuning bending load, which has a similar order of magnitude to the global bending moment, must be implemented in primary strength response. In this paper, the authors present a Simplified Analytical Method (S.A.M.) to estimate the longitudinal strength of a large sloop sailing yacht; this approach has been developed studying a 47-meter yacht by FE technique coupled with classic beam theory and has been verified through the analysis of other two sailing vessels of similar length. A user-friendly routine for this aim, called \u201cStrengthCalc\u201d, has also been create

A simplified method for the evaluation of inertial loads on sailing yachts

The aim of this work was to improve the understanding of dismasting, in view of the development of a new set of Rig Certification Rules specifically aimed at sailing yacht design, In the first phase of this project a preliminary systematic analysis of the dismastings of a large set of boats of different type and size has been carried out. By examining all these events, typical collapse modes have been identified, showing that whereas the traditional approach to mast scantlings is based on static loads, many of the failures took place as a result of severe dynamic loads. For this reason attention has been focused on the dynamic loads acting on the rigging caused by the response of the sailing yacht to waves. Especially in the case of boats with large displacement, these loads could be of a greater magnitude than static ones, and their evaluation must be earned out through seakeeping analysis. In particular pitching motions are extremely important, since they can cause severe accelerations to mast and rigging, possibly leading to mast collapse. Indeed dismasting is a significant event, very dangerous for the crew and very expensive to be repaired. In this paper a systematic study of the pitching behaviour of a database of sailing yachts was carried out. Using these results a simplified formulation is given to quickly evaluate the longitudinal acceleration at the mast centre of gravity. A state-of-the-art process is then used to obtain results in irregular sea states and to compute time series. Despite the small size of the database, this could be regarded as a first step towards the formulation of a simplified method based only on the boat length; this method would be able rapidly to estimate inertial loads due to waves

[Familial papillary carcinoma of the thyroid: biogenetic identification and clinical assessment of 4 families].

The Authors report 9 patients who were affected by familial papillary carcinoma of thyroid These patients were members of 4 families and they were selected in a general group of 97 patients affected by papillary cancer of the thyroid who underwent surgery from 1991 to 1998. The 9 patients were 1st degree relatives: two sisters, two sisters, two sisters and three brothers. The clinical course was similar in patients whether familiar or sporadic group, but average age in first was 10 yrs lower than in the latter group. Functional cervical dissection was needed only one time by lymphatic metastasis. Observed survival was 100% (follow up 92-16 months) and no specific complication was reported. Thyreoglobulin value was less than normal in every patients. Ret linkage analysis was always performed and no rearrangement was found; in 4 patients APC gene was detected but it was never seen. Case studies are consistent with an autosomal dominant trait that shows an high penetrance if associated with a permissive codominant trait. The authors believe that are necessary further studies on this occurrence. In papillary thyroid cancer familiarity was observed in 9.6%, than authors propose that relatives of thyroid papillary cancer should be underwent to screening

Roma-Linz, due scuole di microchirurgia sperimentale per un unico progetto

Introduzione: DAL 2006 L'UNITA' DI MICROCHIRURGIA DI ROMA DIRETTA DAL PROF. ANDREA ORTENSI HA INSTAURATO UNA STRETTA COLLABORAZIONE CON IL MAZ -MIKRO CHIRGISCHES AUSBILDUNGS & FORSCHUNGSZENTRUM- DI LINZ. Metodo: QUESTA COLLABORAZIONE HA PERMESSO E PERMETTERA' DI CONSTITUIRE UNA VERA E PRORPIA SCUOLA INTERNAZIONALE DI MICROCHIRURGIA DOVE GLI SCAMBI CULTURALI POSSANO E, COME GIA HANNO POTUTO, OFFRIRE AI NEOFITI MICROCHIRURGHI LA POSSIBILITA' DI SVILUPPARE NEL CAMPO DELLA RICERCA NUOVE TECNICHE E DI PERFEZIONARE QUELLE GIA AQUISITE Risultati: PRORPIO GRAZIE QUESTA COLLABORAZIONE E' POSSIBILE STUDIARE E SPERIMENTARE NUOVI APPROCCI CHIRURGICI GRAZIE ANCHE ALL'UTILIZZO DI PARTI ANATOMICHE DI CADAVERE, IMPENSABILE IN ITALIA Conclusioni: E' ALLO STUDIO UN NUOVO CORSO TEORICO PRATICO DI MICROCHIRUGIA SPERIMENTALE DA SVOLGERE A ROMA CON LA PARTECIPAZIONE DI TEACHERS ESTERI

Familial papillary carcinoma of the thyroid: A report of nine first-degree relatives of four families

The authors report the occurrence of papillary carcinoma of the thyroid in nine first-degree relatives of four families among a consecutive series of 97 patients with papillary carcinoma of the thyroid who were operated on from 1991 to 1998. Total thyroidectomy was performed in all cases. All patients are alive without evidence of disease after a mean follow-up period of 43 months. Since in our series familial papillary carcinoma of the thyroid was found in 9.3% of patients, we suggest an adequate screening among first-degree relatives of all patients with papillary thyroid carcinoma. Because of reported aggressive behaviour of familial papillary carcinoma of the thyroid, aggressive surgical treatment plus post-operative thyroid remnant ablation with radio-iodine should be warranted in all patients. © 2000 Harcourt Publishers Ltd

Inquadramento clinico della sindrome compartimentale degli arti e trattamento microchirurgico delle lesioni nervose negli esiti

Il tardo 1800 fu il tempo di importanti invenzioni e scoperte della conoscenza medica grazie a nomi come Koch, Lister, Paget, Ollier, Madelung. Richard von Volkmann nel 1869 descrisse un caso clinico che riportava tumefazione dell'avambraccio, dolore e contrattura in flessione delle dita della mano e denominò, la sindrome che oggi porta il suo nome, come "miosite infiammatoria". Nel 1881 notò che"la rapida contrattura doveva esssere riferita all'ischemia". Bardenheuer nel 1911 riportò l'uso della fasciotomia per prevenzione della contrattura; Jepson nel 1926 ne dimostrò i benefici effetti9. Per sindrome compartimentale oggi si intende il complesso di manifestazioni cliniche correlate a un aumento della pressione tissutale oltre un valore soglia all'interno di uno spazio non estensibile che porta ad edema delle strutture all'interno del compartimento, ischemia muscolare e danno da agenti ossidanti. Muscoli, nervi e vasi degli arti attraversano compartimenti osteofasciali relativamente distendibili. La fascia è costituita da tessuto connettivo denso e funziona da membrana extra- ed intracompartimentale. Dalla fascia possono prendere origine inserzioni muscolari, i retinacula o creare guaine fibrose per i tendini; la stessa fascia di alcuni muscoli potrebbe essere indistinguibile dall'epimisio e dal tessuto connettivale che circonda il muscolo stesso. La rivascolarizzazione degli arti in seguito ad un'ischemia prolungata può comportare un edema che può essere sia intra- che extracellulare. Le conseguenze della riperfusione si verificano indipendentemente dalla causa dell'ischemia: embolia, trombosi, reimpianti d'arto, etc. La pressione normale nel compartimento muscolare deve essere inferiore a 10-12 mmHg. La pressione di perfusione compartimentale invece è data dalla pressione arteriosa media (MAP) - pressione compartimentale e deve essere superiore a 70-80 mmHg. Sia un aumento della pressione compartimentale, sia una diminuzione della perfusione può portare ad una sindrome compartimentale9. Scopo del presente lavoro è eseguire un inquadramento clinico-diagnostico della sindrome compartimentale con particolare riguardo alle lesioni nervose spesso associate quale esito di un trattamento inadeguato o tardivo. Vengono riportati i risultati ottenuti su 25 pazienti sottoposti ad intervento chirurgico per lesioni nervose dal gennaio 2003 al gennaio 2006 presso l'Unità Operativa di Microchirurgia Generale "Fabia Mater"-Università di Roma "La Sapienza" (direttore: Prof. A. Ortensi) ed altri centri chirurgici

L’applicazione della microchirurgia in Chirurgia Tiroidea: nostra esperienza

Il XIX secolo è stato caratterizzato da significative innovazioni nel campo della chirurgia, in particolare quella tiroidea. Sebbene la tiroidectomia totale sia ben codificata ed attualmente considerata sicura e standardizzata, tale procedura non è esente dal rischio di complicanze, quali quelle legate alla lesione dei nervi laringei e delle paratiroidi. Per prevenire o ridurre l’incidenza di tali evenienze è fondamentale un’eccellente conoscenza anatomica del collo ed è altrettanto essenziale l’applicazione di una meticolosa tecnica chirurgica. Il ricorso alla microchirurgia e l’uso dei mezzi ottici d’ingrandimento come supporto alla chirurgia tradizionale può rappresentare un valido ausilio nel prevenire le complicanze della chirurgia tiroidea, in particolare negli interventi per recidiva, nelle tiroiditi, nel cancro e nelle linfectomie del collo. Un ulteriore vantaggio offerto dalla tecnica microchirurgica è rappresentato della possibilità di riparare un’eventuale lesione iatrogena del nervo ricorrente contestualmente all’intervento di tiroidectomia. L’applicazione della tecnica microchirurgica agevola, inoltre, la completezza dell’exeresi parenchimale. In caso di patologia benigna tale radicalità evita il rischio di recidive e facilita il compito dell’endocrinologo nel calibrare il fabbisogno dell’organismo all’opoterapia sostitutiva; in caso di cancro, invece, avvantaggia l’eventuale trattamento radiometabolico successivo evitando rischiosi reinterventi di totalizzazione. Per ottenere tale obiettivo, è necessario adottare una tecnica microchirurgica rigorosa basata sulla preparazione dei nervi ricorrenti lungo tutto il decorso cervicale, salvaguardando sempre le paratiroidi con la loro vascolarizzazione. L’applicazione della microchirurgia in chirurgia tiroidea, così come in altri settori della chirurgia generale, richiede un adeguato training sperimentale e clinico e la familiarità con i mezzi ottici di ingrandimento. Viene riportata l’esperienza maturata in un periodo di circa tre anni su un gruppo di pazienti sottoposti a tiroidectomia totale in tecnica microchirurgica presso l’Unità Operativa Complessa di Microchirurgia Generale della Casa di Cura “Fabia Mater” (Direttore Prof. Andrea Ortensi), centro satellite del Dipartimento di Scienze Chirurgiche dell’Università “Sapienza” di Roma