Подготовка беременных с гестозом к оперативному родоразрешению в условиях общей анестезии

БЕРЕМЕННОСТИ ОСЛОЖНЕНИЯГЕСТОЗКЕСАРВО СЕЧЕНИ

The L2 status factor and the declarative/procedural distinction

Bakgrundsspråkens roll i tredjespråksinlärning. Vokabulär och syntax

The L2 proficiency level effect in L3 lexical learning: high-proficiency L2s do not transfer

In this case study we investigate the role of the proficiency level in an earlier formally learned L2 for the transfer source in L3 learning at the lexical level, by comparing two pairs of learners with different proficiency levels in their L2s English, French, Spanish and Italian. The data were gathered with a mirror design: L1 German/L3 Swedish and L1 Swedish/L3 German. The learners were absolute beginners of the L3. Both pairs were recorded over 6 months during conversation with a bilingual German/Swedish interlocutor. The recordings were conducted on a monthly basis. The proficiency levels of all L2s were tested in written tests, based on the CEFR scale. The results show that the proficiency level in the L2s has an impact on the transfer source. The L2s at C1+ level were not transferred, but L2s with lower proficiency levels were. These results confirm what is predicted by the L2 status factor (Bardel & Falk, 2012), namely that a high-proficiency L2 can lose its status as an L2, approaching L1 status, which makes it less susceptible to transfer. The study also confirms the value of case studies in L3 research. Keywords: lexical transfer, proficiency, L3 learning, oral productio

The role of L1 explicit metalinguistic knowledge in L3 oral production at the initial state

In this study we explore the role of explicit metalinguistic knowledge (MLK) of first language (L1) in the learning of a third language (L3). We compare the oral production of 40 participants with varying degrees of explicit MLK of the L1, who are exposed to a completely new L3. In accordance with the second language (L2) status factor, which is further motivated by the distinction between implicit competence and explicit knowledge (Bardel & Falk, 2012; Paradis, 2009), we hypothesize that the participants with low explicit MLK in their L1 will transfer from their L2, and that the participants with high explicit MLK in the L1 will transfer from their L1. The structure of interest is adjective placement, which is the same in the L1 and the L3 (but not in the participants' L2s). The results show that the degree of explicit MLK in the L1 plays a decisive role at the initial state of L3 learning

Meningens motstånd. 29 studenters perspektiv på humaniora

Många röster har på senare tid uppmärksammat att dagens humaniora är i kris. Marginaliserad av en ointresserad offentlighet, ifrågasatt av andra vetenskapliga discipliner, stundtals betvivlad även av humanister själva. Men hur står det egentligen till med denna påstådda krissituation? Och hur upplever studenterna, en omistlig men i debatten ofta åsidosatt grupp, humaniora och humanistiska studier? I antologin Meningens motstånd presenterar 29 studenter verksamma vid Göteborgs Universitet sina perspektiv på humaniora, i ett försök att komplicera och nyansera bilden av detta ständigt omdebatterade vetenskapliga fält. Antologin är en mångfacetterad samling texter, där kärleksfulla försvarstal blandas med brännande kritik och konstruktiva förändringsförslag. Inga enkla svar ges, men i sex tematiska kapitel introduceras nya infallsvinklar både vad gäller humanioras dåtid, nutid och framtid. Sammantaget lyckas skribenterna därmed om inte utrota idén om humanioras kris så definitivt skapa nytt hopp för framtiden

Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay

Objective: The COVID-19 pandemic poses an immense need for accurate, sensitive and high-throughput clinical tests, and serological assays are needed for both overarching epidemiological studies and evaluating vaccines. Here, we present the development and validation of a high-throughput multiplex bead-based serological assay. Methods: More than 100 representations of SARS-CoV-2 proteins were included for initial evaluation, including antigens produced in bacterial and mammalian hosts as well as synthetic peptides. The five best-performing antigens, three representing the spike glycoprotein and two representing the nucleocapsid protein, were further evaluated for detection of IgG antibodies in samples from 331 COVID-19 patients and convalescents, and in 2090 negative controls sampled before 2020. Results: Three antigens were finally selected, represented by a soluble trimeric form and the S1-domain of the spike glycoprotein as well as by the C-terminal domain of the nucleocapsid. The sensitivity for these three antigens individually was found to be 99.7%, 99.1% and 99.7%, and the specificity was found to be 98.1%, 98.7% and 95.7%. The best assay performance was although achieved when utilising two antigens in combination, enabling a sensitivity of up to 99.7% combined with a specificity of 100%. Requiring any two of the three antigens resulted in a sensitivity of 99.7% and a specificity of 99.4%. Conclusion: These observations demonstrate that a serological test based on a combination of several SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay