La Separazione mediante HPLC dei due fenoli isomeri Timolo (p-isopropil-m-cresolo) e Carvacrolo (p-isopropil-o-cresolo)

A method is described for the separation by HPLC of two isomer phenols thymol and carvacrol. Satisfactory resu1ts have been obtained by using a chromatographic column μ Bondapak ,C18 and a solvent system constitued by acetonitrile (40%) and water (60%). The flow rate was 1,5 ml/min. The use of this technique permits determination and dosage of these two phenols in essential oils