Assessment of ERTS-1 imagery as a tool for regional geological analysis in New York State

The author has identified the following significant results. Linear anomalies dominate the new geological information derived from ERTS-1 imagery, total lengths now exceeding 26,500 km. Maxima on rose diagrams for ERTS-1 anomalies correspond well with those for mapped faults and topographic lineaments. Multi-scale analysis of linears shows that single topographic linears at 1:2,500,000 may become dashed linears at 1:1,000,000 aligned zones of shorter parallel, en echelon, or conjugate linears at 1:5000,000, and shorter linears lacking any conspicuous zonal alignment at 1:250,000. Field work in the Catskills suggests that the prominent new NNE lineaments may be surface manifestations of dip slip faulting in the basement, and that it may become possible to map major joint sets over extensive plateau regions directly on the imagery. Most circular features found were explained away by U-2 airfoto analysis but several remain as anomalies. Visible glacial features include individual drumlins, drumlinoids, eskers, ice-marginal drainage channels, glacial lake shorelines, sand plains, and end moraines

Evaluation of ERTS imagery for spectral geological mapping in diverse terranes of New York State

Linear anomalies dominate the new geological information derived from ERTS-1 imagery, total lengths now exceeding 6000 km. Experimentation with a variety of viewing techniques suggests that conventional photogeologic analyses of band 7 results in the location of more than 97 percent of all linears found. The maxima on rose diagrams for ERTS-1 anomalies correspond well with those for mapped faults and topographic lineaments, despite a difference in relative magnitudes of maxima thought due to solar illumination direction. A multiscale analysis of linears showed that single topographic linears at 1:2,500,000 became segmented at 1:1,000,000, aligned zones of shorter parallel, en echelon, or conjugate linears at 1:500,000, and still shorter linears lacking obvious alignment at 1:250,000. Visible glacial features include individual drumlins, best seen in winter imagery, drumlinoids, eskers, ice-marginal drainage channels, glacial lake shorelines and sand plains, and end moraines

Evaluation of ERTS-1 imagery for geological sensing over the diverse geological terrains of New York State

Film positives of ERTS-1 imagery, both as received from NASA and photographically reprocessed, are analyzed by conventional and color additive viewing methods. The imagery reveals bedrock and surficial geological information at various scales. Features which can be identified to varying degrees include boundaries between major tectonic provinces, lithological contacts, foliation trends within massive gneisses, faults, and topographic lineaments. In the present imagery the greatest amount of spectral geology is displayed in the Adirondack region where bedrock geology is strongly linked to topography. Within this basement complex, the most prominantly displayed features are numerous north-northeast trending faults and topographic lineaments, and arcuate east-west valleys developed in some of the weaker metasedimentary rocks. The majority of the faults and lineaments shown on the geologic Map of New York at 1:250,000 appear in the ERTS imagery

Analysis of ERTS-1 linear features in New York State

The author has identified the following significant results. All ERTS-1 linears confirmed to date have topographic expression although they may appear as featureless tonal linears on the imagery. A bias is unavoidably introduced against any linears which may parallel raster lines, lithological trends, or the azimuth of solar illumination. Ground study of ERTS-1 topographic lineaments in the Adirondacks indicates: outcrops along linears are even more rare than expected, fault breccias are found along some NNE lineaments, chloritization and slickensiding without brecciation characterize one EW lineament whereas closely-spaced jointing plus a zone of plastic shear define another. Field work in the Catskills suggests that the prominent new NNE lineaments may be surface manifestations of normal faulting in the basement, and that it may become possible to map major joint sets over extensive plateau regions directly on the imagery. Fall and winter images each display some unique linears, and long linears on the fall image commonly appear as aligned segments on the winter scene. A computer-processed color composite image permitted the extraction or additional information on the shaded side of mountains

Reconnaissance evaluation of Honduran geothermal sites. Una evaluacion por medio de reconocimiento de seis areas geotermicas en Honduras

Six geothermal spring sites were selected on the basis of preliminary investigations conducted in Honduras over the last decade and were evaluated in terms of their development potential. Of the six, the Platanares and San Ignacio sites have high base temperatures and high surface fluid discharge rates and appear to have the best potential for further development as sources of electrical power. A third site, Azacualpa, has a high enough base temperature and discharge rate to be considered as a back-up, but the logistical problems involved in geophysical surveys make it less attractive than the two primary sites. Of the remaining three sites, Pavana may be a source of direct-use heat for local agricultural processing. Sambo Creek and El Olivar have either severe logistical problems that would impede further investigation and development or base temperatures and flow rates that are too low to warrant detailed investigation at this time

Gilbert syndrome redefined: A complex genetic haplotype influences the regulation of glucuronidation.

Gilbert syndrome (GS) is characterized by intermittent unconjugated hyperbilirubinemia without structural liver damage affecting about 10% of the white population. In GS the UGT1A1*28 variant reduces bilirubin conjugation by 70% and is associated with irinotecan and protease inhibitor side effects. Aim of this study was to characterize potential in vivo consequences of UGT1A gene variability in GS. Three hundred GS patients (UGT1A1*28 homozygous) and 249 healthy blood donors (HBD) were genotyped for UGT1A (UGT1A1*28, UGT1A3-66 T>C, UGT1A6*3a, UGT1A7*3) and transporter SNPs (SCLO1B1 p.V174A, SCLO1B1 p.N130D, ABCC2 p.I1324I, ABCC2 -24 UTR) using TaqMan-5'-nuclease-assays. A humanized transgenic UGT1A-SNP and corresponding wild-type mouse model were established carrying the GS-associated UGT1A variant haplotype. UGT1A transcript and protein expression, and transcriptional activation were studied in vivo. Homozygous UGT1A1*28 GS individuals were simultaneously homozygous for UGT1A3-66 T>C (91%), UGT1A6*2a (77%), and UGT1A7*3 (77%). Seventy-six percent of GS and only 9% of HBD were homozygous for the variant haplotype spanning 4 UGT1A genes. SCLO1B1 and ABCC2 single nucleotide polymorphisms (SNPs) showed no differences. In transgenic humanized UGT1A SNP and wild-type mice this UGT1A haplotype led to lower UGT1A mRNA expression and UGT1A protein synthesis. UGT1A transcriptional activation by dioxin, phenobarbital and endotoxin was significantly reduced in SNP mice. CONCLUSION: Our data redefine the genetic basis behind GS. In vivo data studying the genotype present in 76% of GS individuals suggest that transcription and transcriptional activation of glucuronidation genes responsible for conjugation and detoxification is directly affected leading to lower responsiveness. This study suggests that GS should be considered as a potential risk factor for drug toxicity. (HEPATOLOGY 2011.)