Diagnostic Efficacy of Synthesized 2D Digital Breast Tomosynthesis in Multi-ethnic Malaysian Population

Synthesized 2D images can be reconstructed from tomosynthesis images in breast imaging. This study aims to investigate the diagnostic efficacy of synthesized 2D images (C-View) in comparison to full field digital mammography (FFDM) when used with digital breast tomosynthesis (DBT) in multi-ethnic Malaysian population. FFDM and C-View images (n = 380) were independently evaluated by three readers through Breast Imaging Reporting and Data System (BI-RADS) categorisation, breast density and lesion characterisation. Statistical analysis was done comparing sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of C-View + DBT with FFDM + DBT as standard of reference. Very good interreader agreement in BI-RADS category and density assessment between C-View + DBT and FFDM + DBT, with high sensitivity, specificity, PPV and NPV of C-View + DBT when compared with FFDM + DBT. There was comparable PPV between C-View + DBT and FFDM + DBT, with histopathology as gold standard. High level of interreader agreement in BI-RADS category and density assessment for FFDM + DBT and C-View + DBT. There was good agreement between FFDM + DBT and C-View + DBT in mass characterization, and almost perfect agreement in calcification and asymmetric density. 52.2% lower radiation dose incurred when using C-View + DBT. Hence, synthesized 2D images are comparable to FFDM with reduction in radiation dose within the limits of Malaysian multi-ethnic population. © 2019, The Author(s)

Shearwave Elastography Increases Diagnostic Accuracy in Characterization of Breast Lesions

View of the elevation on Nevskiy Prospekt; In 1761 Vallen de la Motte took over the design of the Gostinyy Dvor (1758-1785) in St. Petersburg, a trading market of 200 shops with a central courtyard, which had been started by Bartolomeo Francesco Rastrelli. Vallen de la Motte achieved a clarity of concept and rationality that dispensed with Rastrelli’s planned Rococo decoration; only the handsome composition of the rounded corners hints at the Baroque. Source: Grove Art Online; http://www.oxfordartonline.com/ (accessed 1/15/2009