Cladding of Mg alloy with Zr based BMG Alloy

In the present work, an attempt has been made to clad AZ31 magnesium alloy with Zr-based bulk metallic glassy alloy (Vit-1), by casting method. The interface studies conducted using SEM-EDS line scan indicate that a good bond is formed at the clad interface of Zr and Mg. And the mechanism involved is discussed herein.110Ysciescopu

The use of reinforcement learning algorithms to meet the challenges of an artificial pancreas

Blood glucose control, for example, in diabetes mellitus or severe illness, requires strict adherence to a protocol of food, insulin administration and exercise personalized to each patient. An artificial pancreas for automated treatment could boost quality of glucose control and patients' independence. The components required for an artificial pancreas are: i) continuous glucose monitoring (CGM), ii) smart controllers and iii) insulin pumps delivering the optimal amount of insulin. In recent years, medical devices for CGM and insulin administration have undergone rapid progression and are now commercially available. Yet, clinically available devices still require regular patients' or caregivers' attention as they operate in open-loop control with frequent user intervention. Dosage-calculating algorithms are currently being studied in intensive care patients [1] , for short overnight control to supplement conventional insulin delivery [2] , and for short periods where patients rest and follow a prescribed food regime [3] . Fully automated algorithms that can respond to the varying activity levels seen in outpatients, with unpredictable and unreported food intake, and which provide the necessary personalized control for individuals is currently beyond the state-of-the-art. Here, we review and discuss reinforcement learning algorithms, controlling insulin in a closed-loop to provide individual insulin dosing regimens that are reactive to the immediate needs of the patient

Diagnosis of enteric fever in the emergency department: a retrospective study from Pakistan

Background:Enteric fever is one of the top differential diagnoses of fever in many parts of the world. Generally, the diagnosis is suspected and treatment is initiated based on clinical and basic laboratory parameters.Aims: The present study identifies the clinical and laboratory parameters predicting enteric fever in Patients visiting the emergency department of a tertiary care hospital in Pakistan.Methods:This is a retrospective chart review of all adult Patients with clinically suspected enteric fever admitted to the hospital through the emergency department during a 5-year period (2000-2005).Results:A total of 421 emergency department Patients were admitted to the hospital with suspected enteric fever. There were 53 cases of blood culture-positive enteric fever and 296 disease-negative cases on culture. The mean age in the blood culture-positive group was 27 years (SD: 10) and in the group with negative blood culture for enteric fever, 35 years (SD: 15) with a male to female ratio of 1:0.6 in both groups. Less than half (48%) of all Patients admitted with suspected enteric fever had the discharge diagnosis of enteric fever, of which only 13% of the Patients had blood culture/serologically confirmed enteric fever. None of the common clinical and laboratory parameters differed between enteric fever-positive Patients and those without it.Conclusion:Commonly cited clinical and laboratory parameters were not able to predict enteric fever

How the required precision influences the way we intercept a moving object

Do people perform a given motor task differently if it is easy than if it is difficult? To find out, we asked subjects to intercept moving virtual targets by tapping on them with their fingers. We examined how their behaviour depended on the required precision. Everything about the task was the same on all trials except the extent to which the fingertip and target had to overlap for the target to be considered hit. The target disappeared with a sound if it was hit and deflected away from the fingertip if it was missed. In separate sessions, the required precision was varied from being quite lenient about the required overlap to being very demanding. Requiring a higher precision obviously decreased the number of targets that were hit, but it did not reduce the variability in where the subjects tapped with respect to the target. Requiring a higher precision reduced the systematic deviations from landing at the target centre and the lag-one autocorrelation in such deviations, presumably because subjects received information about smaller deviations from hitting the target centre. We found no evidence for lasting effects of training with a certain required precision. All the results can be reproduced with a model in which the precision of individual movements is independent of the required precision, and in which feedback associated with missing the target is used to reduce systematic errors. We conclude that people do not approach this motor task differently when it is easy than when it is difficult. © 2013 Springer-Verlag Berlin Heidelberg

Understanding the retinal basis of vision across species

The vertebrate retina first evolved some 500 million years ago in ancestral marine chordates. Since then, the eyes of different species have been tuned to best support their unique visuoecological lifestyles. Visual specializations in eye designs, large-scale inhomogeneities across the retinal surface and local circuit motifs mean that all species' retinas are unique. Computational theories, such as the efficient coding hypothesis, have come a long way towards an explanation of the basic features of retinal organization and function; however, they cannot explain the full extent of retinal diversity within and across species. To build a truly general understanding of vertebrate vision and the retina's computational purpose, it is therefore important to more quantitatively relate different species' retinal functions to their specific natural environments and behavioural requirements. Ultimately, the goal of such efforts should be to build up to a more general theory of vision

Effect of Mo on the High-Temperature Creep Resistance and Machinability of a Recycled Al-Alloy with High Iron Impurity

Reported work focuses on the effect of morphology of the Fe-rich intermetallic phases on the machinability of Al-alloy containing > 2wt.% Fe, obtained from automotive scrap. Effect of Mo addition on the microstructure, high-temperature impression creep and thereby the machinability of the Al-recycled alloy were studied. The machinability of the recycled alloy was estimated by investigating the built-up-edge (BUE) and surface roughness (R (a)). SEM-EDS and TEM-SADP studies have shown that the crystal structure (BCC) of the Al8Fe2Si phase remained unchanged; however, Mo replaced few Fe atoms with little effect on the lattice dimension. It has been found that the addition of Mo to the recycled alloy suppresses the formation of beta-phase (Al5FeSi) by suppressing the peritectic transformation of alpha (Al8Fe2Si) phase. Such suppression is found to improve the high-temperature creep resistance and the machinability with the increase in the Mo addition level.1113sciescopu