148 research outputs found

    Cooperation after War: International Development in Bosnia, 1995 to 1999

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    This paper discusses how predispositions, incentives, the number and heterogeneity of participants, and leadership (Faerman et al. 2001) jointly influenced the international effort to develop Bosnia and Herzegovina. International coalitions, task forces, and advisory groups are increasingly charged with implementing reforms following civil conflict. This requires a complex web of interorganizational relationships among NGOS, donors and host nations at both global and ā€˜groundā€™ levels. To better understand development assistance, attention must be paid to the relationships between these varied players. We find that four factors influenced relationships between policy, donor, and implementing organizations; and those strained relationships, in turn, affected development success. The paper draws on interviews, conducted in Bosnia, with 43 development professionals, observation of development meetings in Tuzla and Sarajevo, and review of related documents from international development programs.international development, interorganizational relationships and cooperation

    Cooperation after war

    Get PDF
    This paper discusses how predispositions, incentives, the number and heterogeneity of participants, and leadership (Faerman et al. 2001) jointly influenced the international effort to develop Bosnia and Herzegovina. International coalitions, task forces, and advisory groups are increasingly charged with implementing reforms following civil conflict. This requires a complex web of interorganizational relationships among NGOS, donors and host nations at both global and "ground" levels. To better understand development assistance, attention must be paid to the relationships between these varied players. We find that four factors influenced relationships between policy, donor, and implementing organizationsand those strained relationships, in turn, affected development success. The paper draws on interviews, conducted in Bosnia, with 43 development professionals, observation of development meetings in Tuzla and Sarajevo, and review of related documents from international development programs

    Participative Practices and In-Role Performance in the Korean Local Government: Focusing on an Individuals Perceptions of Human Resource Development Practices

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    Considering inconsistent results in the extant literature regarding whether participative practices improve performance, we focused on the mediating roles of an individuals perception of human resource development practices, including training and career development, on the relationship between the two constructs. We began by examining the validity of the constructs under the study. Next, using structural equation modeling, we found that an individuals perception of career development fully mediates the relationships between the two participative practices, including participation and empowerment, and in-role performance. In addition, the findings indicated that individuals perception of training fully mediates the relationship between empowerment and performance, but failed to play a mediating role on the relationship between participation and performance

    The time-frequency method of signal analysis in internal combustion engine diagnostics

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    The paper presents the results of the study of applicability of time-frequency correlation functions to solving the problems of internal combustion engine fault diagnostics. The proposed methods are theoretically justified and experimentally tested. In particular, the method's applicability is illustrated by the example of specially generated signals that simulate the vibration of an engine both during the normal operation and in the case of a malfunction in the system supplying fuel to the cylinders. This method was confirmed during an experiment with an automobile internal combustion engine. The study offers the main findings of the simulation and the experiment and highlights certain characteristic features of time-frequency autocorrelation functions that allow one to identify malfunctions in an engine's cylinder. The possibility in principle of using time-frequency correlation functions in function testing of the internal combustion engine is demonstrated. The paper's conclusion proposes further research directions including the application of the method to diagnosing automobile gearboxes

    Development of a Novel Virtual Screening Cascade Protocol to Identify Potential Trypanothione Reductase Inhibitors

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    The implementation of a novel sequential computational approach that can be used effectively for virtual screening and identification of prospective ligands that bind to trypanothione reductase (TryR) is reported. The multistep strategy combines a ligand-based virtual screening for building an enriched library of small molecules with a docking protocol (AutoDock, X-Score) for screening against the TryR target. Compounds were ranked by an exhaustive conformational consensus scoring approach that employs a rank-by-rank strategy by combining both scoring functions. Analysis of the predicted ligand-protein interactions highlights the role of bulky quaternary amine moieties for binding affinity. The scaffold hopping (SHOP) process derived from this computational approach allowed the identification of several chemotypes, not previously reported as antiprotozoal agents, which includes dibenzothiepine, dibenzooxathiepine, dibenzodithiepine, and polycyclic cationic structures like thiaazatetracyclo-nonadeca-hexaen-3-ium. Assays measuring the inhibiting effect of these compounds on T. cruzi and T. brucei TryR confirm their potential for further rational optimization

    Molecular structure of the largemouth bass (Micropterus salmoides) Myf5 gene and its effect on skeletal muscle growth

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    Myogenic Regulatory Factors (MRFs), a family of basic helix-loop-helix (bHLH) transcription factors, play important roles in regulating skeletal muscle development and growth. Myf5, the primary factor of MRFs, initiates myogenesis. Its expression pattern during somitomyogenesis in some fish has been revealed. To further study its effect on fish muscle during postembryonic growth, characterization and function analysis of myf5 cDNA were carried out in largemouth bass. The 1,093Ā bp cDNA sequence was identified by RT-PCR and 3ā€²RACE, then the ORF of Myf5 cDNA was cloned into the expression vector pcDNA3.1(āˆ’)/mycHisB. The recombinant plasmid pcDNA3.1(āˆ’)/mycHisB-Myf5 was injected into the dorsal muscle of tilapias. RT-PCR and histochemical results showed that the exogenous gene was transcribed and translated inĀ vivo. Its effect on muscle growth focused on myofiber hypertrophy in white muscle 60Ā days post injection. This indicated that overexpression of Myf5 can promote myogenesis during the fish muscle postembryonic growth period
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