Quantitative sensory testing with Von Frey monofilaments in patients with allodynia - What are we quantifying?

The International Association for the Study of Pain defines allodynia as pain due to a stimulus that does not normally provoke pain and hyperalgesia as an increased response to a stimulus, which is normally painful. However, does "normally painful" mean "any stimulation of nociceptors" or "the subjective pain response?" We argue that "normally painful" should not mean "any stimulation of nociceptors," as Von Frey monofilaments may evoke a pricking sensation-which implies the involvement of nociceptors-without necessarily leading to a subjective pain perception. In this paper, we propose that the diagnosis of either allodynia or hyperalgesia should be based on the patient's report, that is, painful versus not painful, rather than on the (sub) type of afferent fiber involved

Computing Tools for the SMEFT

International audienceThe increasing interest in the phenomenology of the Standard Model Effective Field Theory (SMEFT), has led to the development of a wide spectrum of public codes which implement automatically different aspects of the SMEFT for phenomenological applications. In order to discuss the present and future of such efforts, the "SMEFT-Tools 2019" Workshop was held at the IPPP Durham on the 12th-14th June 2019. Here we collect and summarize the contents of this workshop