The Good, the Bad and the Ugly: A Study of the Organization through the Lens of Popular Films of the Western World

This chapter examined portrayals of the morality of organizations using the lens of Western films. The work explored six decades of film, analyzing the organizational contexts and their agents, in order to understand filmmakers’ and audiences’ perceptions of organizational settings. In order to examine the organization as an entity within film, this chapter provided a content analysis of plot summaries from a purposefully selected body of top grossing box office films spanning 60 years. The plot summaries constituted a strong basis for identifying the characteristics of the organization as they are largely descriptive in nature and as such do not offer any evaluation or analysis of the film. Any assumptions about the character of organizations (or their members/employees) are unconscious, and as such they constitute a verbal description of what competent observers would say has occurred within the film. The plots were coded to reveal perceptions of positive, neutral, or negative organizational contexts and actions. This approach exposed the filmmakers symbolic placing of the organization in order to provide backdrops for the narrative. The plot analysis revealed that throughout the decades there has been a sophisticated portrayal in film of the role of the organization and the agents therein. A generally negative view of organizational contexts was demonstrated, with only religion and education shown as positive within the films selected. It was recognized that there would be value in extending this research to analyze a larger body of works. The selection criteria resulted in a wide but not comprehensive corpus of film genres. The body of works was sufficient to reveal the complexity of attitudes to organizational values and delivery which has evolved through time. Different selection criteria and more substantial narrative text could serve to confirm these results. Further implications for future research were discussed. While in the real-life sphere, there has been an emphasis on organizational standards and “corporate governance” delivering ethical exemplars, the film contexts highlight the complexities of delivering trusted organizations. The reality that there remains the potential for organizational corruption is well understood by the general public and clearly depicted within the film world. The conceptual contribution is original as limited work has been conducted on the organizational context in films. This work revealed the possibility of using this approach to further develop a greater understanding of perceptions of organizations

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

Development of the vascular system depends on the highly coordinated actions of a variety of angiogenic regulators. Several of these regulators are members of the tyrosine kinase superfamily, including VEGF receptors and angiopoietin receptors, Tie1 and Tie2. Tyrosine kinase signaling is counter-regulated by the activity of tyrosine phosphatases, including vascular endothelial protein tyrosine phosphatase (VE-PTP), which has previously been shown to modulate Tie2 activity. We generated mice in which VE-PTP is replaced with a reporter gene. We confirm that VE-PTP is expressed in endothelium and also show that VE-PTP is highly expressed in the developing outflow tract of the heart and later is expressed in developing heart valves. Vasculogenesis occurs normally in mice lacking VE-PTP; however, angiogenesis is abnormal. Angiogenic defects in VE-PTP-null mice were most pronounced in the yolk sac and include a complete failure to elaborate the primitive vascular scaffold into higher-order branched arteries, veins, and capillaries. VE-PTP continues to be expressed into adulthood in the vasculature and heart valves, suggesting later roles in vascular development or homeostasis. VE-PTP is also expressed in the vasculature of growing tumors, suggesting that VE-PTP may be a new potential target for angiogenic therapies