Test of the QCD vacuum with the sources in higher representations

Recent accurate measurement by G.Bali of static potentials between sources in various SU(3) representations provides a crucial test of the QCD vacuum and of different theoretical approaches to the confinement. In particular, the Casimir scaling of static potentials found for all measured distances implies a strong suppression of higher cumulants and a high accuracy of the Gaussian stochastic vacuum. Most popular models are in conflict with these measurements.Comment: LaTeX, 7 page

Hubble Space Telescope Observations of M32: The Color-Magnitude Diagram

We present a V-I color-magnitude diagram for a region 1'-2' from the center of M32 based on Hubble Space Telescope WFPC2 images. The broad color-luminosity distribution of red giants shows that the stellar population comprises stars with a wide range in metallicity. This distribution cannot be explained by a spread in age. The blue side of the giant branch rises to M_I ~ -4.0 and can be fitted with isochrones having [Fe/H] ~ -1.5. The red side consists of a heavily populated and dominant sequence that tops out at M_I ~ -3.2, and extends beyond V-I=4. This sequence can be fitted with isochrones with -0.2 < [Fe/H] < +0.1, for ages running from 15 Gyr to 5 Gyr respectively. We do not find the optically bright asymptotic giant branch stars seen in previous ground-based work and argue that the majority of them were artifacts of crowding. Our results are consistent with the presence of the infrared-luminous giants found in ground-based studies, though their existence cannot be directly confirmed by our data. There is little evidence for an extended or even a red horizontal branch, but we find a strong clump on the giant branch itself. If the age spread is not extreme, the distribution of metallicities in M32 is considerably narrower than that of the closed-box model of chemical evolution, and also appears somewhat narrower than that of the solar neighborhood. Overall, the M32 HST color-magnitude diagram is consistent with the average luminosity-weighted age of 8.5 Gyr and [Fe/H] = -0.25 inferred from integrated spectral indices.Comment: 22 pages, AASTeX, aaspp4 and flushrt style files included, 11 postscript figures, figures 1,2,5,7, and 8 available at ftp://bb3.jpl.nasa.gov/pub/m32 . Submitted to the Astronomical Journa

Supernovae in Early-Type Galaxies: Directly Connecting Age and Metallicity with Type Ia Luminosity

We have obtained optical spectra of 29 early-type (E/S0) galaxies that hosted type Ia supernovae (SNe Ia). We have measured absorption-line strengths and compared them to a grid of models to extract the relations between the supernova properties and the luminosity-weighted age/composition of the host galaxies. The same analysis was applied to a large number of early-type field galaxies selected from the SDSS spectroscopic survey. We find no difference in the age and abundance distributions between the field galaxies and the SN Ia host galaxies. We do find a strong correlation suggesting that SNe Ia in galaxies whose populations have a characteristic age greater than 5 Gyr are ~ 1 mag fainter at V(max) than those found in galaxies with younger populations. However, the data cannot discriminate between a smooth relation connecting age and supernova luminosity or two populations of SN Ia progenitors. We find that SN Ia distance residuals in the Hubble diagram are correlated with host-galaxy metal abundance, consistent with the predictions of Timmes, Brown & Truran (2003). The data show that high iron abundance galaxies host less-luminous supernovae. We thus conclude that the time since progenitor formation primarily determines the radioactive Ni production while progenitor metal abundance has a weaker influence on peak luminosity, but one not fully corrected by light-curve shape and color fitters. Assuming no selection effects in discovering SNe Ia in local early-type galaxies, we find a higher specific SN Ia rate in E/S0 galaxies with ages below 3 Gyr than in older hosts. The higher rate and brighter luminosities seen in the youngest E/S0 hosts may be a result of recent star formation and represents a tail of the "prompt" SN Ia progenitors.Comment: 44 pages, 11 figures, 4 tables; ApJ Accepted (Sept. 20, 2008 issue

Noninvasive Home Mechanical Ventilation in Adult Myotonic Dystrophy Type 1:A Systematic Review

Introduction: Chronic hypercapnic respiratory failure induces considerable morbidity and mortality in patients with myotonic dystrophy type 1 (DM1). This study systematically reviews the effects of noninvasive home mechanical ventilation (HMV) on gas exchange, quality of life, survival, and compliance in DM1 patients. Methods: A systematic Medline and Embase search was performed (January 1995 to January 2020). Records were screened for eligibility criteria, data were extracted from included studies, and risk of bias was assessed. We present findings mainly using a narrative synthesis. Results: Twenty-eight relevant full-text articles were screened for eligibility criteria. Nine studies were included. Randomized controlled trials were not found. Studies had either an observational (n = 8) or interventional (n = 1) design. In the pooled data analysis, HMV showed to improve mean oxygen saturation with 4.8% and decreased mean carbon dioxide values with 3 mm Hg. Compliance varied widely between studies, from no use to more than 12 h per day. Quality of life was not studied extensively, but some studies reported positive effects of HMV on symptoms of chronic respiratory failure. HMV may improve survival in DM1 patients with chronic hypercapnic respiratory failure. Conclusion: This review shows that HMV can improve gas exchange and relieve symptoms with a possible survival benefit in DM1 patients with chronic hypercapnic respiratory failure. Future studies should focus on developing strategies to optimize the timing of HMV initiation and to promote compliance

Three-Dimensional Planning and Use of Individualized Osteotomy-Guiding Templates for Surgical Correction of Kyphoscoliosis:A Technical Case Report

OBJECTIVE: We have described the use of 3-dimensional (3D) virtual planning and 3D printed patient-specific osteotomy templates in the surgical correction of a complex spinal deformity. Pedicle subtraction osteotomies (PSOs) for the correction of severe spinal deformities are technically demanding procedures with a risk of major complications. In particular, operations of the severely deformed spine call for new, more precise, methods of surgical planning. The new 3D technology could result in new possibilities for the surgical planning of spinal deformities. METHODS: We present the case of severe congenital kyphoscoliosis in a young girl with skeletal dysplasia. A closing wedge-extended PSO was 3D virtual planned using medical computer design software. After the optimal 3D-wedge procedure was planned, individualized osteotomy-guiding templates were designed for translation of the planned PSO to the surgical procedure. During surgery, the PSO was performed using the osteotomy templates. Successful correction of the kyphoscoliosis was realized. RESULTS: The kyphosis was successfully reduced using a wedge-shaped extended PSO using preoperative 3D virtual planning, assisted by 3D-printed individualized osteotomy-guiding templates. CONCLUSIONS: In addition to direct translation of the planned PSO for surgery, the 3D planning also facilitated a detailed preoperative evaluation, greater insight into the case-specific anatomy, and accurate planning of the required correction

ACE inhibition attenuates radiation-induced cardiopulmonary damage

BACKGROUND AND PURPOSE: In thoracic irradiation, the maximum radiation dose is restricted by the risk of radiation-induced cardiopulmonary damage and dysfunction limiting tumor control. We showed that radiation-induced sub-clinical cardiac damage and lung damage in rats mutually interact and that combined irradiation intensifies cardiopulmonary toxicity. Unfortunately, current clinical practice does not include preventative measures to attenuate radiation-induced lung or cardiac toxicity. Here, we investigate the effects of the ACE inhibitor captopril on radiation-induced cardiopulmonary damage.MATERIAL AND METHODS: After local irradiation of rat heart and/or lungs captopril was administered orally. Cardiopulmonary performance was assessed using biweekly breathing rate measurements. At 8weeks post-irradiation, cardiac hemodynamics were measured, CT scans and histopathology were analyzed.RESULTS: Captopril significantly improved breathing rate and cardiopulmonary density/structure, but only when the heart was included in the radiation field. Consistently, captopril reduced radiation-induced pleural and pericardial effusion and cardiac fibrosis, resulting in an improved left ventricular end-diastolic pressure only in the heart-irradiated groups.CONCLUSION: Captopril improves cardiopulmonary morphology and function by reducing acute cardiac damage, a risk factor in the development of radiation-induced cardiopulmonary toxicity. ACE inhibition should be evaluated as a strategy to reduce cardiopulmonary complications induced by radiotherapy to the thoracic area.</p

Casimir scaling as a test of QCD vacuum

Recent accurate measurements of static potentials between sources in various representations of the gauge group SU(3) performed by G.Bali provide a crucial test of the QCD vacuum models and different approaches to confinement. The Casimir scaling of the potential observed for all measured distances implies strong suppression of higher cumulant contributions. The consequences for the instanton vacuum model and the spectrum of the QCD string are also discussed.Comment: LaTeX, 15 pages, 1 figur

The Advanced Camera for Surveys General Catalog: Structural Parameters for Approximately Half A Million Galaxies

We present the Advanced Camera for Surveys General Catalog (ACS-GC), a photometric and morphological database using publicly available data obtained with the Advanced Camera for Surveys (ACS) instrument on the Hubble Space Telescope. The goal of the ACS-GC database is to provide a large statistical sample of galaxies with reliable structural and distance measurements to probe the evolution of galaxies over a wide range of look-back times. The ACS-GC includes approximately 470,000 astronomical sources (stars + galaxies) derived from the AEGIS, COSMOS, GEMS, and GOODS surveys. Galapagos was used to construct photometric (SEXTRACTOR) and morphological (GALFIT) catalogs. The analysis assumes a single Sersic model for each object to derive quantitative structural parameters. We include publicly available redshifts from the DEEP2, COMBO-17, TKRS, PEARS, ACES, CFHTLS, and zCOSMOS surveys to supply redshifts (spectroscopic and photometric) for a considerable fraction (similar to 74%) of the imaging sample. The ACS-GC includes color postage stamps, GALFIT residual images, and photometry, structural parameters, and redshifts combined into a single catalog.NASA/ESA GO-10134, GO-09822, GO-09425.01, GO-09583.01, GO-9500NASA NAS 5-26555NSF AST00-71048NASA LTSA NNG04GC89GESO Paranal Observatory LP175.A-0839Astronom

Galactic rotation curves inspired by a noncommutative-geometry background

This paper discusses the observed at rotation curves of galaxies in the context of noncommutative geometry. The energy density of such a geometry is diffused throughout a region due to the uncertainty encoded in the coordinate commutator. This intrinsic property appears to be sufficient for producing stable circular orbits, as well as attractive gravity, without the need for dark matter.Comment: 12 pages, 3 figures. Published in Gen.Rel.Grav. 44 (2012) 905-91