Instrumental Resolution of the Chopper Spectrometer 4SEASONS Evaluated by Monte Carlo Simulation

We performed simulations of the resolution function of the 4SEASONS spectrometer at J-PARC by using the Monte Carlo simulation package McStas. The simulations showed reasonably good agreement with analytical calculations of energy and momentum resolutions by using a simplified description. We implemented new functionalities in Utsusemi, the standard data analysis tool used in 4SEASONS, to enable visualization of the simulated resolution function and predict its shape for specific experimental configurations.Comment: 8 pages, 5 figure

Chronic Pseudomonas aeruginosa Infection as the Pathogenesis of Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD), resulted from tobacco smoking, has an extremely poor prognosis and is a major cause of chronic morbidity and mortality worldwide. In this chapter, we review the role of bacterial infection on the pathogenesis of COPD, with a particular focus on Pseudomonas aeruginosa. Chronic infection with P. aeruginosa has been shown to contribute to COPD pathogenesis under certain conditions. In addition, P. aeruginosa is a major factor influencing severe symptoms, acute exacerbation, and the progression of COPD. Treatment for chronic P. aeruginosa infection may become a new strategy for addressing COPD