692 research outputs found

    Drag Force in a Charged N=4 SYM Plasma

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    Following recent developments, we employ the AdS/CFT correspondence to determine the drag force exerted on an external quark that moves through an N=4 super-Yang-Mills plasma with a non-zero R-charge density (or, equivalently, a non-zero chemical potential). We find that the drag force is larger than in the case where the plasma is neutral, but the dependence on the charge is non-monotonic.Comment: 16 pages, 1 eps figure; v2: references added, typos fixed; v3: more general ansatz, new nontrivial solution obtained, nonmonotonicity of the drag force made explicit in new figure, version to appear in JHE

    Even-denominator fractional quantum Hall physics in ZnO

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    The fractional quantum Hall (FQH) effect emerges in high-quality two-dimensional electron systems exposed to a magnetic field when the Landau-level filling factor, ν_e, takes on a rational value. Although the overwhelming majority of FQH states have odd-denominator fillings, the physical properties of the rare and fragile even-denominator states are most tantalizing in view of their potential relevance for topological quantum computation. For decades, GaAs has been the preferred host for studying these even-denominator states, where they occur at ν_e = 5/2 and 7/2. Here we report an anomalous series of quantized even-denominator FQH states outside the realm of III–V semiconductors in the MgZnO/ZnO 2DES electron at ν_e = 3/2 and 7/2, with precursor features at 9/2; all while the 5/2 state is absent. The effect in this material occurs concomitantly with tunability of the orbital character of electrons at the chemical potential, thereby realizing a new experimental means for investigating these exotic ground states

    Structural Model of the mIgM B-Cell Receptor Transmembrane Domain From Self-Association Molecular Dynamics Simulations

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    Antigen binding to B-cell antigen receptors (BCRs) followed by signaling initiates the humoral immune response. The signaling is intimately coupled to nanoclustering of BCRs and their sorting to specific membrane domains, a process that is ruled by interactions between the BCR transmembrane domain and lipids. While the structure of the extracellular domains of BCRs has been resolved, little is known about the configuration of the constituting four immunoglobulin domains spanning the membrane. Here, we modeled the structure of the transmembrane (TM) domain of the IgM B-cell receptor using self-assembly coarse-grained molecular dynamics simulations. The obtained quaternary structure was validated against available experimental data and atomistic simulations. The IgM-BCR-TM domain configuration shows a 1:1 stoichiometry between the homodimeric membrane-bound domain of IgM (mIgM) and a Ig-α/Ig-β heterodimer. The mIgM homodimer is based on an asymmetric association of two mIgM domains. We show that a specific site of the Ig-α/Ig-β heterodimer is responsible for the association of IgM-BCRs with lipid rafts. Our results further suggest that this site is blocked in small-sized IgM-BCR clusters. The BCR TM structure provides a molecular basis for the previously suggested dissociation activation model of B-cell receptors. Self-assembly molecular dynamics simulations at the coarse-grained scale here proved as a versatile tool in the study of receptor complexes

    Black Branes in a Box: Hydrodynamics, Stability, and Criticality

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    We study the effective hydrodynamics of neutral black branes enclosed in a finite cylindrical cavity with Dirichlet boundary conditions. We focus on how the Gregory-Laflamme instability changes as we vary the cavity radius R. Fixing the metric at the cavity wall increases the rigidity of the black brane by hindering gradients of the redshift on the wall. In the effective fluid, this is reflected in the growth of the squared speed of sound. As a consequence, when the cavity is smaller than a critical radius the black brane becomes dynamically stable. The correlation with the change in thermodynamic stability is transparent in our approach. We compute the bulk and shear viscosities of the black brane and find that they do not run with R. We find mean-field theory critical exponents near the critical point.Comment: 23 pages, 3 figures. v2: added comments on first-order phase transitio

    Perturbations of anti-de Sitter black holes

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    I review perturbations of black holes in asymptotically anti-de Sitter space. I show how the quasi-normal modes governing these perturbations can be calculated analytically and discuss the implications on the hydrodynamics of gauge theory fluids per the AdS/CFT correspondence. I also discuss phase transitions of hairy black holes with hyperbolic horizons and the dual superconductors emphasizing the analytical calculation of their properties.Comment: 25 pages, 4 figures, prepared for the proceedings of the 5th Aegean Summer School "From Gravity to Thermal Gauge Theories: the AdS/CFT Correspondence," Milos, Greece, September 2009

    Angiofil®-mediated visualization of the vascular system by microcomputed tomography: a feasibility study

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    Visualization of the vascular systems of organs or of small animals is important for an assessment of basic physiological conditions, especially in studies that involve genetically manipulated mice. For a detailed morphological analysis of the vascular tree, it is necessary to demonstrate the system in its entirety. In this study, we present a new lipophilic contrast agent, Angiofil®, for performing postmortem microangiography by using microcomputed tomography. The new contrast agent was tested in 10 wild-type mice. Imaging of the vascular system revealed vessels down to the caliber of capillaries, and the digital three-dimensional data obtained from the scans allowed for virtual cutting, amplification, and scaling without destroying the sample. By use of computer software, parameters such as vessel length and caliber could be quantified and remapped by color coding onto the surface of the vascular system. The liquid Angiofil® is easy to handle and highly radio-opaque. Because of its lipophilic abilities, it is retained intravascularly, hence it facilitates virtual vessel segmentation, and yields an enduring signal which is advantageous during repetitive investigations, or if samples need to be transported from the site of preparation to the place of actual analysis, respectively. These characteristics make Angiofil® a promising novel contrast agent; when combined with microcomputed tomography, it has the potential to turn into a powerful method for rapid vascular phenotyping

    Chapter 3 Ecosystem Services and Disservices of Mangrove Forests and Salt Marshes

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    Coastal wetlands such as mangrove forests and saltmarshes provide a range of important benefits to people, broadly defined as ecosystem services. These include provisioning services such as fuelwood and food, regulating services such as carbon sequestration and wave attenuation, and various tangible and intangible cultural services. However, strong negative perceptions of coastal wetlands also exist, often driven by the perceived or actual ecosystem disservices that they also produce. These can include odour, a sense of danger, and their real or perceived role in vector and disease transmission (e.g., malaria). This review provides an introduction to the ecosystem services and disservices concepts, and highlights the broad range of services and disservices provided by mangrove forests and saltmarshes. Importantly, we discuss the key implications of ecosystem services and disservices for the management of these important coastal ecosystems. Ultimately, a clear binary does not exist between ecosystem services and disservices; an ecosystem service to one stakeholder can be viewed as a disservice to another, or a service can change seasonally into a disservice, and vice versa. It is not enough to only consider the beneficial ecosystem services that coastal wetlands provide: instead, we need to provide a balanced view of coastal wetlands that incorporates the complexities that exist in how humans relate to and interact with these important coastal ecosystems
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