19 research outputs found
Heterogeneity of respiratory distress syndrome: risk factors and morbidity associated with early and late gestation disease
Full text linkInvestigating increased admissions to neonatal intensive care in England between 1995 and 2006: data linkage study using Hospital Episode Statistics
Full text linkDoes lung ultrasound score predict the need for surfactant in extremely preterm neonates?
No full textPredicting respiratory distress syndrome at birth using a fast test based on spectroscopy of gastric aspirates: 2. Clinical part
No full text
Supraglottic airway devices for surfactant treatment: systematic review and meta-analysis
No full textObjective: To compare surfactant administration via supraglottic airway device (SAD) vs. nasal CPAP alone or INSURE. Study design: A systematic search of PubMed, EMBASE, SCOPUS, Cochrane Central Register of Controlled Trials and Clinicaltrials.gov was performed. Articles meeting inclusion criteria (RCT, surfactant administration via SAD, laryngeal mask, I-gel) were assessed Results: Five RCTs were eligible. Surfactant administration via SAD reduced the need for intubation/mechanical ventilation (RR 0.57, 95%CI 0.38–0.85) and short-term oxygen requirements (MD −8.00, 95%CI −11.09 to −4.91) compared to nCPAP alone. Surfactant administration via SAD reduced the need for intubation/mechanical ventilation (RR 0.43, 95%CI 0.31–0.61), but increased short-term oxygen requirements (MD 3.10, 95%CI 0.51–5.69) compared to INSURE approach. Conclusions: In preterm infants with RDS, surfactant administration via SAD reduces the need for intubation/mechanical ventilation. Overall, available literature includes few, small, poor-quality studies. Surfactant administration via SAD should be limited to clinical trials. © 2018, Springer Nature America, Inc
