357 research outputs found
Chromosomal-level assembly of the Asian Seabass genome using long sequence reads and multi-layered scaffolding
- Author
- A Bairoch
- A Christoffels
- A Gurevich
- A Kozomara
- A McKenna
- A Mitchell
- A Morgulis
- A Morgulis
- A Pradhan
- A Reiner
- A Rodriguez-Mari
- A Stamatakis
- A Yates
- AI Makunin
- AJ Enright
- AL Price
- AL Price
- Alan Christoffels
- Aleksey Komissarov
- Alexey Tupikin
- Amy Hin Yan Tong
- Andrey A. Yurchenko
- AR Quinlan
- B Langmead
- B Star
- C Berthelot
- C Camacho
- C Holt
- C Wang
- Chen-Shan Chin
- CS Chin
- D Brawand
- D Ellinghaus
- DA Benson
- Darrell Green
- DC Hardie
- Dean R. Jerry
- DH Alexander
- Doreen Lau
- DR Kelley
- DRS-K C. Jerry
- E Casacuberta
- E. TG Staristina
- EW Myers
- F Abascal
- F Chen
- F Yang
- FC Jones
- FJ Krsticevic
- Fritz J. Sedlazeck
- G Abrusan
- G Benson
- G Lin
- G Marcais
- G Parra
- G Parra
- G Tamazian
- GH Yue
- GH Yue
- Gopikrishna Gopalapillai
- Gregory W. Vurture
- GS Slater
- GT Valente
- H Li
- H Saiga
- Heiner Kuhl
- HH Kazazian Jr.
- I Braasch
- Inna S. Kuznetsova
- IS Kuznetsova
- J Castresana
- J Eid
- J Huerta-Cepas
- J Jurka
- J Lin
- James P. Drake
- JG Ruby
- JN Volff
- JN Volff
- Jolly M. Saju
- Jonas Korlach
- JS Chew
- Junhui Jiang
- K Howe
- K Katoh
- K Prufer
- Kathiresan Purushothaman
- KD Pruitt
- KJ Hoff
- KP Koepfli
- KW Tzung
- Lawrence S. Hon
- László Orbán
- M Blanchette
- M Kanehisa
- M Kasahara
- M Kolmogorov
- M Krzywinski
- M Martin
- M Schartl
- M Tarailoâ-Graovac
- M Tine
- MA Larkin
- Mario Jonas
- Marsel Kabilov
- Matthew Boitano
- MB Stocks
- MG Grabherr
- Michael C. Schatz
- MJ Chaisson
- MR Friedlander
- N Siegel
- Natascha M. Thevasagayam
- NM Thevasagayam
- O Jaillon
- O Otero
- P Cingolani
- P Ravi
- P Schattner
- P Shannon
- P Xu
- Paul M. Richardson
- PE Warburton
- Peter Van Heusden
- R Kajitani
- R Lorenz
- R Luo
- R Moore
- R Pethiyagoda
- R Poulter
- R She
- R Sreenivasan
- Ramkumar Lachumanan
- RD Ward
- RD Ward
- Richard Hall
- RJ Roberts
- S Chen
- S Guindon
- S Hoegg
- S Hoegg
- S Koren
- S Vij
- S Zhou
- Sai Rama Sridatta Prakki
- Sarah Mwangi
- SF Altschul
- Shubha Vij
- Si Lok
- Si Yan Ngoh
- Siddharth Singh
- Simon Moxon
- SM Kielbasa
- Sridhar Sivasubbu
- Stanley Kimbung Mbandi
- Stephen J. O'Brien
- Stephen W. Turner
- T Anantharaman
- Tamás Dalmay
- Tansyn H. Noble
- TD Wu
- TF DeLuca
- TH O'Hare
- TLO Davis
- TS Anantharaman
- Tyler Garvin
- U Consortium
- U Grimholt
- V Douard
- V Ravi
- Vinaya Kumar Katneni
- Vinod Scaria
- Vladimir Trifonov
- W Xue
- WC Liew
- Woei Chang Liew
- WS Davidson
- X Huang
- X Zheng
- XG Wang
- XG Wang
- Xueyan Shen
- Y Guiguen
- Y Han
- Y Hashiguchi
- Y Moriya
- Y Sato
- Y Sato
- Y Sato
- Z Lai
- Ø Hammer
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2016
- Field of study
We report here the ~670 Mb genome assembly of the Asian seabass (Lates calcarifer), a tropical marine teleost. We used long-read sequencing augmented by transcriptomics, optical and genetic mapping along with shared synteny from closely related fish species to derive a chromosome-level assembly with a contig N50 size over 1 Mb and scaffold N50 size over 25 Mb that span ~90% of the genome. The population structure of L. calcarifer species complex was analyzed by re-sequencing 61 individuals representing various regions across the species' native range. SNP analyses identified high levels of genetic diversity and confirmed earlier indications of a population stratification comprising three clades with signs of admixture apparent in the South-East Asian population. The quality of the Asian seabass genome assembly far exceeds that of any other fish species, and will serve as a new standard for fish genomics
On the relation of mind wandering and ADHD symptomatology
- Author
- B Baird
- BT DeShazo
- C Johnston
- C Ottaviani
- CK Whalen
- D Knowles
- Daniel Smilek
- DM Fergusson
- E Barron
- EF Risko
- FJ Ruby
- G Polanczyk
- GA Overbey
- GA Shaw
- H Pashler
- J Krause
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- James Allan Cheyne
- JC McVay
- Jonathan Smallwood
- JSA Carriere
- JT Nigg
- JW Schooler
- KK Szpunar
- LA Adler
- LM Giambra
- MA Killingsworth
- MJ Kane
- P Seli
- P Seli
- P Seli
- Paul Seli
- RA Barkley
- RA Barkley
- RA Barkley
- S Mannuzza
- SP Hinshaw
- SP Hinshaw
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Left dorsolateral prefrontal cortex supports context-dependent prioritisation of off-task thought
- Author
- A Eklund
- A Turnbull
- AM Dale
- B Baird
- B Fischl
- B Fischl
- B Medea
- BA Smeekens
- BT Yeo
- C O’Callaghan
- C O’Callaghan
- D Lakens
- D Sridharan
- DB Levinson
- DC Van Essen
- FJ Ruby
- FR Richter
- H-T Wang
- HM Bonnici
- J Davey
- J He
- J Jiang
- J Rummel
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- J Smallwood
- JC McVay
- JC McVay
- JC McVay
- JD Power
- JD Power
- JW Kam
- K Christoff
- K Murphy
- K Wiech
- KJ Friston
- KJ Gorgolewski
- M Corbetta
- M Irish
- M Irish
- M Konishi
- M Konishi
- M Petrides
- M Sormaz
- M Xia
- MD Fox
- MD Mrazek
- MF Glasser
- MF Mason
- MK Robison
- N Unsworth
- N Unsworth
- NU Dosenbach
- P Kanske
- R Ciric
- R Leech
- S Vossel
- S Whitfield-Gabrieli
- T Yarkoni
- Y Behzadi
- ZS Saad
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
When environments lack compelling goals, humans often let their minds wander to thoughts with greater personal relevance; however, we currently do not understand how this context-dependent prioritisation process operates. Dorsolateral prefrontal cortex (DLPFC) maintains goal representations in a context-dependent manner. Here, we show this region is involved in prioritising off-task thought in an analogous way. In a whole brain analysis we established that neural activity in DLPFC is high both when ‘on-task’ under demanding conditions and ‘off-task’ in a non-demanding task. Furthermore, individuals who increase off-task thought when external demands decrease, show lower correlation between neural signals linked to external tasks and lateral regions of the DMN within DLPFC, as well as less cortical grey matter in regions sensitive to these external task relevant signals. We conclude humans prioritise daydreaming when environmental demands decrease by aligning cognition with their personal goals using DLPFC
Clinical and Non-Clinical Aspects of Distal Radioulnar Joint Instability
- Author
- Anderson ML
- Atzei A
- Bednar MS
- Bowers WH
- Breen TF
- Burkhartt SS
- Cox FJ
- Dameron TB
- Darrach W
- Davidson PA
- Ekenstam F
- Epner RA
- Essex-Lopresti P
- Feldon P
- Gerber A
- Gibson A
- Gofton WT
- Goldner JL
- Hagert CG
- Herbert T
- Hotchkiss RN
- Hui FC
- IB Schipper
- Jupiter JB
- Kapandji I
- Kim JP
- King GJ
- Kleinman WB
- Lawler E
- Lester B
- Levinsohn EM
- Lindau T
- Lindau T
- Lo IK
- Magee T
- Mikic ZD
- Millard GM
- Mino De
- Mino DE
- Mino DE
- MME Wijffels
- Nakamura R
- Nakamura R
- Noda K
- Paley D
- Paley D
- Palmer AK
- Palmer AK
- Park MJ
- Pfaeffle HJ
- Pirela-Cruz MA
- Pogue DJ
- Poitevin LA
- PRG Brink
- Ruby LK
- Scheker LR
- Schuind F
- Seo KN
- Smith AM
- Spinner M
- Staron RB
- Szabo RM
- Thiru RG
- Tsai TM
- Watanabe H
- Watanabe H
- Watson H
- Wechsler RJ
- Publication venue
- Bentham Open
- Publication date
- 01/01/2012
- Field of study
Untreated distal radioulnar joint (DRUJ) injuries can give rise to long lasting complaints. Although common, diagnosis and treatment of DRUJ injuries remains a challenge. The articulating anatomy of the distal radius and ulna, among others, enables an extensive range of forearm pronosupination movements. Stabilization of this joint is provided by both intrinsic and extrinsic stabilizers and the joint capsule. These structures transmit the load and prevent the DRUJ from luxation during movement. Several clinical tests have been suggested to determine static or dynamic DRUJ stability, but their predictive value is unclear. Radiologic evaluation of DRUJ instability begins with conventional radiographs in anterioposterior and true lateral view. If not conclusive, CT-scan seems to be the best additional modality to evaluate the osseous structures. MRI has proven to be more sensitive and specific for TFCC tears, potentially causing DRUJ instability. DRUJ instability may remain asymptomatic. Symptomatic DRUJ injuries treatment can be conservative or operative. Operative treatment should consist of restoration of osseous and ligamenteous anatomy. If not successful, salvage procedures can be performed to regain stability
lin-28 Controls the Succession of Cell Fate Choices via Two Distinct Activities
- Author
- A Esquela-Kerscher
- A Polesskaya
- AE Rougvie
- AL Abbott
- AS Pepper
- B Causier
- B Hook
- B Wightman
- B Xu
- B Xu
- Bhaskar Vadla
- BJ Reinhart
- BR Maller Schulman
- C Qiu
- Christian Heine
- CM Hammell
- CQ Nguyen
- DH Yang
- DS Fay
- E Balzer
- E Balzer
- E Piskounova
- EE Caygill
- EG Moss
- EG Moss
- EG Moss
- Eric G. Moss
- FG Wulczyn
- FJ Slack
- H Zhu
- I Bussing
- I Heo
- I Heo
- J Yu
- JA West
- JE Abrahante
- JE Sulston
- Jennifer Alaimo
- JG Ruby
- JP Hagan
- K Koh
- K Seggerson
- Kevin Kemper
- KJ Livak
- L Ding
- L Timmons
- L Zhang
- M Jeon
- M Lagos-Quintana
- M Li
- MA Newman
- NC Lau
- NJ Lehrbach
- NS Sokol
- PM Van Wynsberghe
- RC Lee
- RC Lee
- S Peng
- S Roush
- S Yokoyama
- SR Viswanathan
- SR Viswanathan
- Susan E. Mango
- SY Lin
- T Del Rio-Albrechtsen
- TD Resnick
- V Ambros
- V Ambros
- V Ambros
- V Ambros
- WB Wood
- WP Kloosterman
- Y Hong
- YC Lin
- Publication venue
- Public Library of Science
- Publication date
- 22/03/2012
- Field of study
lin-28 is a conserved regulator of cell fate succession in animals. In Caenorhabditis elegans, it is a component of the heterochronic gene pathway that governs larval developmental timing, while its vertebrate homologs promote pluripotency and control differentiation in diverse tissues. The RNA binding protein encoded by lin-28 can directly inhibit let-7 microRNA processing by a novel mechanism that is conserved from worms to humans. We found that C. elegans LIN-28 protein can interact with four distinct let-7 family pre-microRNAs, but in vivo inhibits the premature accumulation of only let-7. Surprisingly, however, lin-28 does not require let-7 or its relatives for its characteristic promotion of second larval stage cell fates. In other words, we find that the premature accumulation of mature let-7 does not account for lin-28's precocious phenotype. To explain let-7's role in lin-28 activity, we provide evidence that lin-28 acts in two steps: first, the let-7–independent positive regulation of hbl-1 through its 3′UTR to control L2 stage-specific cell fates; and second, a let-7–dependent step that controls subsequent fates via repression of lin-41. Our evidence also indicates that let-7 functions one stage earlier in C. elegans development than previously thought. Importantly, lin-28's two-step mechanism resembles that of the heterochronic gene lin-14, and the overlap of their activities suggests a clockwork mechanism for developmental timing. Furthermore, this model explains the previous observation that mammalian Lin28 has two genetically separable activities. Thus, lin-28's two-step mechanism may be an essential feature of its evolutionarily conserved role in cell fate succession
Present state and future perspectives of using pluripotent stem cells in toxicology research
- Author
- A Abuin
- A Albini
- A Beqqali
- A Bradley
- A Colman
- A Dolci
- A Fraichard
- A Hansen
- A Krtolica
- A Lesman
- A Lombardo
- A Lorico
- A Mehta
- A Moretti
- A Nagy
- A Nagy
- A Norstrom
- A Schnerch
- A Seifinejad
- A Seiler
- A Seiler
- A Soto-Gutierrez
- A Suzuki
- A Urbach
- AA Filipczyk
- AB McLean
- AD Ebert
- AD Ebert
- AG Hendrickx
- AG Smith
- AH Piersma
- AI Di Domenico
- AK Peters
- AM Newman
- AM Wobus
- AM Wobus
- AM Wobus
- AM Wobus
- AM Wobus
- AM Wobus
- Anna M. Wobus
- Anon
- B Ekwall
- B Thyagarajan
- BA Schwetz
- BC Heng
- BE Petersen
- BE Reubinoff
- BP Schmidt
- BW Kahan
- BW Phillips
- BY Hu
- C Buecker
- C Dani
- C Denning
- C Denning
- C Freund
- C Kim
- C Mummery
- C Strubing
- C Xu
- C Xu
- CE Murry
- CK Lim
- CL Stewart
- D Anderson
- D Hockemeyer
- D Hoof Van
- D Huangfu
- D Kim
- D Laustriat
- D Zhao
- DA Eastmond
- DA Kerr
- DC Hay
- DC Hay
- DC Hay
- DE Kehoe
- DJ Tester
- DL Cockroft
- E Chiao
- E Dolgin
- E Genschow
- E Kolossov
- E Schmelzer
- E Sonoda
- EJ Topol
- EM Jones-Villeneuve
- F Hattori
- F Soldner
- FJ Müller
- G Amabile
- G Brolen
- G Laschinski
- G Lee
- G Pless
- G Tzimas
- GJ Sullivan
- GL Kimmel
- GR Martin
- H Baharvand
- H Baharvand
- H Basma
- H Gai
- H Green
- H Guenou
- H Jakob
- H Liang
- H Liu
- H Nau
- H Pei
- H Reinecke
- H Shirahashi
- H Song
- H Spielmann
- H Spielmann
- H Spielmann
- H Spielmann
- H Vaziri
- H Xie
- H Xue
- H Zaehres
- H Zhou
- I Huber
- I Kehat
- I Kola
- IF Ben-Nun
- IF Khan
- IG Brons
- IH Park
- J Cai
- J Czyz
- J Czyz
- J Favor
- J Fletcher
- J Hanna
- J Jensen
- J Liu
- J Rohwedel
- J Rohwedel
- J Rohwedel
- J Rohwedel
- J Satin
- J Synnergren
- J Yu
- J Yu
- J Zhang
- J Zou
- JA Bantle
- JA Thomson
- JC Mohr
- JC Moore
- JE Trosko
- JG Hengstler
- JL Resnick
- JM Polo
- JQ He
- JT Dimos
- K Abe
- K Chen
- K Dolnikov
- K Eggan
- K Guan
- K Hübner
- K Kaji
- K Kim
- K Ko
- K Mitsui
- K Narwani
- K Okita
- K Prelle
- K Saha
- K Sakurai
- K Sasaki
- K Si-Tayeb
- K Si-Tayeb
- K Suzuki
- K Takahashi
- K Takahashi
- K Vojnits
- K Woltjen
- KA Atkinson
- KA D’Amour
- KD Wilson
- KM Ruby
- KR Boheler
- KR Chien
- KR Thomas
- L Bu
- L Hareng
- L Kang
- L Rambhatla
- L Sartiani
- L Yang
- L Zwi
- LA Donehower
- LB Russell
- LB Russell
- LC Stevens
- LC Stevens
- LC Stevens
- LM Hondeghem
- LT Lock
- M Baker
- M Balls
- M Brito-Martins
- M Drab
- M Ek
- M Ieda
- M Jalving
- M Kessel
- M Klemm
- M Klemm
- M Krishnamoorthy
- M Leist
- M Mikkola
- M Nakayama
- M Pekkanen-Mattila
- M Pekkanen-Mattila
- M Puceat
- M Reppel
- M Skrzypiec-Spring
- M Snir
- M Stadtfeld
- M Stadtfeld
- M Stojkovic
- M Verwei
- M Wernig
- M Zalzman
- MA Baxter
- MA Laflamme
- MG Guenther
- MG Perino
- MH Chin
- MJ Boland
- MJ Evans
- MJ Evans
- MJ Shamblott
- MK Edwards
- MK Jonsson
- MM Schmidt
- MT Donato
- MW McBurney
- N Chalasani
- N Gilbert
- N Lavon
- N Lavon
- N Lee
- N Maherali
- N Shiraki
- N Terada
- N Yokoo
- NA Brown
- NI zur Nieden
- NJ Hewitt
- O Bluteau
- O Caspi
- O Caspi
- O Sedan
- P Blyszczuk
- P Löser
- P Marx-Stoelting
- P Sancho-Bru
- P Sarkar
- P Sartipy
- Peter Löser
- PJ Tesar
- PP Sloun Van
- PR West
- PS Knoepfler
- PW Andrews
- PW Burridge
- Q Feng
- Q Zhou
- QL Ying
- R Buesen
- R Fassler
- R Graichen
- R Jelinek
- R Meamar
- R Pal
- R Passier
- R Passier
- RB Cervantes
- RE Horton
- RE Schwartz
- RK Li
- RK Rowntree
- RL Brinster
- RL Davis
- RL Williams
- RM Marion
- RN Moore
- RN Moore
- RP Davis
- S Adler
- S Adler
- S Agarwal
- S Boehn
- S Bremer
- S Bremer
- S Bremer
- S Conrad
- S Ehnert
- S Irion
- S Lin
- S Niebruegge
- S Nishikawa
- S Peng
- S Russmann
- S Snykers
- S Strickland
- S Yao
- SJ Flora
- SJ Gwak
- SR Braam
- SR Khetani
- ST Rashid
- T Cao
- T Ishii
- T Ishii
- T Mosmann
- T Ochiya
- T Peura
- T Shimizu
- T Söderdahl
- T Tenzen
- T Touboul
- T Vierbuchen
- T Zdravkovic
- TC Doetschman
- TC Stummann
- TC Stummann
- TC Stummann
- TG Otsuji
- TP Zwaka
- TT Peura
- TW Sadler
- U Sehlmeyer
- U Sehlmeyer
- U Sehlmeyer
- U Sehlmeyer
- UH Ehling
- UH Ehling
- V Krizhanovsky
- VA Maltsev
- VE Papaioannou
- W Rust
- W Zhou
- WH Zimmermann
- WM Westerink
- WZ Zhu
- X Carvajal-Vergara
- X Zeng
- X Zeng
- X Zhang
- XQ Xu
- XQ Xu
- XQ Xu
- XY Zhao
- Y Chung
- Y Duan
- Y Duan
- Y Matsui
- Y Mayshar
- Y Shi
- Y Toyooka
- Z Song
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
The use of novel drugs and chemicals requires reliable data on their potential toxic effects on humans. Current test systems are mainly based on animals or in vitro–cultured animal-derived cells and do not or not sufficiently mirror the situation in humans. Therefore, in vitro models based on human pluripotent stem cells (hPSCs) have become an attractive alternative. The article summarizes the characteristics of pluripotent stem cells, including embryonic carcinoma and embryonic germ cells, and discusses the potential of pluripotent stem cells for safety pharmacology and toxicology. Special attention is directed to the potential application of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) for the assessment of developmental toxicology as well as cardio- and hepatotoxicology. With respect to embryotoxicology, recent achievements of the embryonic stem cell test (EST) are described and current limitations as well as prospects of embryotoxicity studies using pluripotent stem cells are discussed. Furthermore, recent efforts to establish hPSC-based cell models for testing cardio- and hepatotoxicity are presented. In this context, methods for differentiation and selection of cardiac and hepatic cells from hPSCs are summarized, requirements and implications with respect to the use of these cells in safety pharmacology and toxicology are presented, and future challenges and perspectives of using hPSCs are discussed
Beetroot supplementation improves the physiological responses to incline walking
- Author
- A Hernández
- A Vanhatalo
- AA Kenjale
- Adrian Gray
- AE Minetti
- AJ Webb
- AM Jones
- BC Breese
- BC Ruby
- C Oggioni
- Craig Lawlor
- FJ Larsen
- FW Kolkhorst
- G Vernillo
- H-M Choi
- J Kelly
- J Whitfield
- Jamie Highton
- JS Gottschall
- JS Staab
- KE Lansley
- KE Lansley
- KH Wesseling
- LJ Wylie
- Luke Waldron
- M Amman
- M Gilchrist
- M Gilchrist
- M Horiuchi
- MA Sloniger
- Mark Waldron
- NS Bryan
- O Peacock
- OM Shannon
- P Porcelli
- PM Christensen
- PN Ainslie
- PN Ainslie
- R Margaria
- RK Boorsma
- SJ Bailey
- SJ Bailey
- SJ Bailey
- SJ Bailey
- SK Ferguson
- V Bond
- V Bond
- V Kapil
- V Kapil
- WG Hopkins
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
The final publication is available at Springer via http://dx.doi.org/10.1007/s00421-018-3843-xPurpose: We investigated the effects of an acute 24-h nitrate-rich beetroot juice supplement (BR) on the energy cost, exercise efficiency and blood pressure responses to intermittent walking at different gradients. Methods: In a double-blind, cross-over design, eight participants were provided with a total of 350 ml of nitrate-rich (~20.5 mmol nitrate) BR or placebo (PLA) across 24-h before completing intermittent walking at 3 km/h on treadmill at gradients of 1%, 5%, 10%, 15% and 20%. Results: Resting mean arterial pressure (MAP) was ~4.1% lower after BR (93 vs. 89 mmHg; P = 0.001), as well as during exercise (102 vs. 99 mmHg; P = 0.011) and recovery (97 vs. 94 mmHg; P = 0.001). Exercising (1227 vs. 1129 ml/min P < 0.001) and end-stage (1404 vs. 1249 ml/min; P = 0.002) oxygen uptake (O2) was lower in BR compared to PLA, which was accompanied by an average reduction in phase II ̇O2 amplitude (1067 vs. 940 ml/min; P = 0.025). Similarly, recovery O2 (509 vs. 458 ml/min; P = 0.001) was lower in BR. Whole-blood potassium concentration increased from pre-post exercise in PLA (4.1 ± 0.3 vs. 4.5 ± 0.3 mmol/L; P = 0.013) but not BR (4.1 ± 0.31 vs. 4.3 ± 0.2 mmol/L; P = 0.188). Conclusions: Energy cost of exercise, recovery of O2, MAP and blood markers were ameliorated after BR. Previously reported mechanisms explain these findings, which are more noticeable during less efficient walking at steep gradients (15-20%). These findings have practical implications for hill-walkers
Measurement of the tt¯tt¯ production cross section in pp collisions at √s=13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abed Abud A
- Abeling K
- Abhayasinghe DK
- Abidi SH
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Achkar B
- Adam Bourdarios C
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akbiyik M
- Akimov AV
- Al Khoury K
- Alberghi GL
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
- Ali S
- Aliev M
- Alimonti G
- Allaire C
- Allbrooke BMM
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alunno Camelia E
- Alvarez Estevez M
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
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- Zeißner SV
- Zemaityte G
- Zeng JC
- Zenin O
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/11/2021
- Field of study
A measurement of four-top-quark production using proton-proton collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider corresponding to an integrated luminosity of 139 fb−1 is presented. Events are selected if they contain a single lepton (electron or muon) or an opposite-sign lepton pair, in association with multiple jets. The events are categorised according to the number of jets and how likely these are to contain b-hadrons. A multivariate technique is then used to discriminate between signal and background events. The measured four-top-quark production cross section is found to be 26+17−15 fb, with a corresponding observed (expected) significance of 1.9 (1.0) standard deviations over the background-only hypothesis. The result is combined with the previous measurement performed by the ATLAS Collaboration in the multilepton final state. The combined four-top-quark production cross section is measured to be 24+7−6 fb, with a corresponding observed (expected) signal significance of 4.7 (2.6) standard deviations over the background-only predictions. It is consistent within 2.0 standard deviations with the Standard Model expectation of 12.0 ± 2.4 fb
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
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- Zhemchugov A
- Zheng J
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- Zheng X
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- Zhong D
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- Zhu CG
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- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
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- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Measurements of W+W−+ ≥ 1 jet production cross-sections in pp collisions at s = 13 TeV with the ATLAS detector
- Author
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- Abbott B
- Abbott DC
- Abed Abud A
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
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- Abreu H
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- Abusleme Hoffman AC
- Acharya BS
- Achkar B
- Adam Bourdarios C
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- Adamczyk L
- Adamek L
- Adelman J
- Adiguzel A
- Adorni S
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- Alberghi GL
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- Alconada Verzini MJ
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- Zeißner SV
- Zemaityte G
- Zeng JC
- Zenin O
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- Zhemchugov A
- Zheng Z
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- Zhulanov V
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- Zimine NI
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- Zinonos Z
- Ziolkowski M
- Zoccoli A
- Zoch K
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/06/2021
- Field of study
Fiducial and differential cross-section measurements of W+W− production in
association with at least one hadronic jet are presented. These measurements are sensitive
to the properties of electroweak-boson self-interactions and provide a test of perturbative
quantum chromodynamics and the electroweak theory. The analysis is performed using
proton-proton collision data collected at p
s = 13TeV with the ATLAS experiment, corresponding
to an integrated luminosity of 139 fb−1. Events are selected with exactly one oppositely
charged electron-muon pair and at least one hadronic jet with a transverse momentum
of pT > 30 GeV and a pseudorapidity of |�| < 4.5. After subtracting the background
contributions and correcting for detector effects, the jet-inclusive W+W−+ � 1 jet fiducial
cross-section and W+W−+ jets differential cross-sections with respect to several kinematic
variables are measured. These measurements include leptonic quantities, such as the lepton
transverse momenta and the transverse mass of the W+W− system, as well as jet-related
observables such as the leading jet transverse momentum and the jet multiplicity. Limits on
anomalous triple-gauge-boson couplings are obtained in a phase space where interference
between the Standard Model amplitude and the anomalous amplitude is enhanced
- …