38 research outputs found
The SOS Pilot Study: a RCT of routine oxygen supplementation early after acute stroke—effect on recovery of neurological function at one week
- Author
- A Bruno
- A Rocco
- AB Singhal
- AB Singhal
- AM Rowat
- Anushka Warusevitane
- B Indredavik
- C Roffe
- C Roffe
- C Roffe
- C Roffe
- C Roffe
- Christine Roffe
- Christoph Kleinschnitz
- E Flynn
- FB Young
- Frank Lally
- G Sulter
- G Sulter
- HA Kontos
- HP Adams Jr
- J Bamford
- J Nuutinen
- JM McCord
- John Hodsoll
- JY Yager
- K Ali
- K Ali
- KF Schulz
- Khalid Ali
- L Koops
- L Lewis
- M Bennett
- M Wijesinghe
- M Yamamoto
- Martin Allen
- MP Mattson
- N Bateman
- NR Sims
- OM Ronning
- P Appelros
- P Thorvaldsen
- Peter Crome
- Peter Jones
- PH Chan
- PJ Crack
- RJ Wityk
- S Liu
- S Nakajima
- Sarah Pountain
- Sheila Sills
- T Brott
- T Sugawara
- Y Silva
- Y Silva
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2011
- Field of study
Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no significant benefit at 7 and 12 months. This pilot study reports the effects of routine oxygen supplementation for 72 hours on oxygen saturation and neurological outcomes at 1 week after a stroke
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
- A Campbell
- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
- A Doms
- A Donovan
- A Donovan
- A Dávalos
- A Gaeta
- A Garny
- A Gnjec
- A Gomes
- A Gopalakrishnan
- A Hald
- A Henney
- A Hirayama
- A Hoffmann
- A Huber
- A Hugman
- A Iannetti
- A Ide-Ektessabi
- A Jacobs
- A Jeyabalan
- A Kahvejian
- A Karrar
- A Kasztler
- A Kibel
- A Kocyigit
- A Kotha
- A Kumral
- A Lass
- A Lecube
- A Lewén
- A Lotery
- A Maggio
- A Malek
- A Malik
- A Mantovani
- A Matsuzawa
- A Mitra
- A Monge
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- A Mutti
- A Nijnik
- A Nunomura
- A Nunomura
- A Patt
- A Persson
- A Pietrangelo
- A Piga
- A Pirat
- A Post
- A Pradhan
- A Protti
- A Rattner
- A Ravati
- A Rehman
- A Reynolds
- A Richmond
- A Roetto
- A Roetto
- A Rostom
- A Rumbold
- A Russo
- A Rötig
- A Saltelli
- A Saltelli
- A Sandek
- A Sassano
- A Scalbert
- A Scalbert
- A Scalbert
- A Sica
- A Smahi
- A Sola
- A Stintzi
- A Szewczyk
- A Taguchi
- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
- A Wagner
- A Wagner
- A Wagner
- A Wagner
- A Wojas-Pelc
- A Wong
- A Xu
- A Yoritaka
- A Yoshimura
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- Ad hoc committee on systemic lupus erythematosus response criteria for fatigue
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- Y Sai
- Y Sai
- Y Sun
- Y Takada
- Y Wang
- Y Wang
- Y Wei
- Y Wei
- Y Wu
- Y Wu
- Y Zhang
- Y Zhang
- Y Zhang
- Y Zhao
- Y Zheng
- YE Henrotin
- YF Chu
- YH Lee
- YH Suh
- YH Wei
- YJ Surh
- YJ Surh
- YJ Surh
- YK Wu
- YM Kim
- YS Keum
- YS Sohn
- YX Ma
- YZ Fang
- Z Cai
- Z Cai
- Z Cheng
- Z Pei
- Z Serdar
- Z Tong
- Z Tong
- Z Yu
- Z Zhang
- ZD Liu
- ZD Liu
- ZE Karanjawala
- ZE Suntres
- ZI Cabantchik
- ZZ Chong
- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Cerebral blood flow and plasma hypoxanthine in relation to surfactant treatment
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Radical orbital decompression for severe dysthyroid exophthalmos
- Author
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- Field of study
Antioxidant Activities of Plants Used in Traditional Medicine in Turkey
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury.
- Author
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study
RTP801 Amplifies Nicotinamide Adenine Dinucleotide Phosphate Oxidase-4–Dependent Oxidative Stress Induced by Cigarette Smoke
- Author
- Publication venue
- 'American Thoracic Society'
- Publication date
- Field of study
Long-Term Exposure to Inorganic Mercury Leads to Oxidative Stress in Peripheral Blood of Adult Rats
- Author
- A Szász
- AEA Moneim
- B Ho-Tin-Noé
- B Liu
- B Sharma
- B Shenker
- DD Zhang
- DM Bailey
- EM Alissa
- F Lorscheider
- F Teixeira
- FB Teixeira
- FB Teixeira
- G Zuchtriegel
- GL Ellman
- H Milnerowicz
- H Satoh
- HC Çubukçu
- HI Kohn
- IB Dhouib
- J-D Park
- JB Nevado
- JL Franco
- JM Hansen
- JM McCord
- KA Winship
- KL Penta
- LJ Zhang
- M Aschner
- M Berglund
- M Rufino
- M Valko
- MA Boujbiha
- MG Corrêa
- P Diaz-Vivancos
- P Feng
- P-L Chiang
- R Lauwerys
- R Re
- RA Bernhoft
- RR Martín-Doimeadios
- RV Albuquerque
- S Ahmad
- S Azimi
- S Omanwar
- S Percário
- T Takahashi
- TR Schalcher
- V Branco
- W Aragao
- Y Ma
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Magnetic domain walls as broadband spin wave and elastic magnetisation wave emitters
- Author
- A Barra
- A Conca
- A Vansteenkiste
- AE Lord
- AM Alekseev
- AV Chumak
- B Lenk
- B Mozooni
- B Mozooni
- B Wiele Van de
- C Hengst
- C-Y Liang
- E Schlömann
- FB Mushenok
- IA Shimokhin
- J McCord
- J Mullenix
- J Trützschler
- JM Winter
- K Wagner
- M Foerster
- M Lohman
- M Weiler
- MP Silverman
- NJ Whitehead
- P Graczyk
- P Pirro
- PE Roy
- RB Holländer
- S Cherepov
- S Wintz
- SW Yuan
- TJ Silva
- U Queitsch
- V Kruglyak
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Nitrosylated Hemoglobin Levels in Human Venous Erythrocytes Correlate with Vascular Endothelial Function Measured by Digital Reactive Hyperemia
- Author
- A Carr
- A Deisseroth
- A Nohria
- AJ Flammer
- AL Kleschyov
- B Fink
- B Piknova
- Bernard Gallez
- C Napoli
- Christophe Beauloye
- CL Hawkins
- DA Svistunenko
- F Desjardins
- FB Jensen
- H Li
- I Azarov
- Irina I. Lobysheva
- JC Maxwell
- Jean-Luc Balligand
- JM McCord
- JT Kuvin
- K Kirima
- M Paolini
- M Siervo
- MM Cortese-Krott
- MT Gladwin
- N Hogg
- NM Hamburg
- OA Paniagua
- P Kleinbongard
- Paolo Madeddu
- Pauline Biller
- PL Huang
- PM Vanhoutte
- Q Chen
- RA Sunde
- RE Glover
- TH Han
- Z Reiner
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study