19 research outputs found

    Overnachtingshaven Lobith. Aanvullend advies voor richtlijnen voor het milieueffectrapport

    Get PDF
    Contains fulltext : 36283.pdf (publisher's version ) (Open Access)11 p

    Ergebnisse der Belastungsinventur Baden-Wuerttemberg 1983 Darstellung der Ernaehrungs- und Belastungsverhaeltnisse bei Fichte und Tanne. Dokumentationsband

    No full text
    Copy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

    Ergebnisse der Belastungsinventur Baden-Wuerttemberg 1983 Darstellung der Ernaehrungs- und Belastungsverhaeltnisse bei Fichte und Tanne. Dokumentationsband

    No full text
    Copy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

    Randomized trial of longer-term therapy for symptoms attributed to Lyme Disease

    No full text
    BACKGROUND\nThe treatment of persistent symptoms attributed to Lyme disease remains controversial. We assessed whether longer-term antibiotic treatment of persistent symptoms attributed to Lyme disease leads to better outcomes than does shorter-term treatment.\nMETHODS\nIn a randomized, double-blind, placebo-controlled trial conducted in Europe, we assigned patients with persistent symptoms attributed to Lyme disease--either related temporally to proven Lyme disease or accompanied by a positive IgG or IgM immunoblot assay for Borrelia burgdorferi--to receive a 12-week oral course of doxycycline, clarithromycin plus hydroxychloroquine, or placebo. All study groups received open-label intravenous ceftriaxone for 2 weeks before initiating the randomized regimen. The primary outcome measure was health-related quality of life, as assessed by the physical-component summary score of the RAND-36 Health Status Inventory (RAND SF-36) (range, 15 to 61, with higher scores indicating better quality of life), at the end of the treatment period at week 14, after the 2-week course of ceftriaxone and the 12-week course of the randomized study drug or placebo had been completed.\nRESULTS\nOf the 281 patients who underwent randomization, 280 were included in the modified intention-to-treat analysis (86 patients in the doxycycline group, 96 in the clarithromycin-hydroxychloroquine group, and 98 in the placebo group). The SF-36 physical-component summary score did not differ significantly among the three study groups at the end of the treatment period, with mean scores of 35.0 (95% confidence interval [CI], 33.5 to 36.5) in the doxycycline group, 35.6 (95% CI, 34.2 to 37.1) in the clarithromycin-hydroxychloroquine group, and 34.8 (95% CI, 33.4 to 36.2) in the placebo group (P=0.69; a difference of 0.2 [95% CI, -2.4 to 2.8] in the doxycycline group vs. the placebo group and a difference of 0.9 [95% CI, -1.6 to 3.3] in the clarithromycin-hydroxychloroquine group vs. the placebo group); the score also did not differ significantly among the groups at subsequent study visits (P=0.35). In all study groups, the SF-36 physical-component summary score increased significantly from baseline to the end of the treatment period (P<0.001). The rates of adverse events were similar among the study groups. Four serious adverse events thought to be related to drug use occurred during the 2-week open-label ceftriaxone phase, and no serious drug-related adverse event occurred during the 12-week randomized phase.\nCONCLUSIONS\nIn patients with persistent symptoms attributed to Lyme disease, longer-term antibiotic treatment did not have additional beneficial effects on health-related quality of life beyond those with shorter-term treatment. (Funded by the Netherlands Organization for Health Research and Development ZonMw; PLEASE ClinicalTrials.gov number, NCT01207739.).</p

    Untersuchungen zur Reaktionsweise junger Klonfichten (Picea abies (L.) Karst.) auf Trockenstress und Magnesiummangel

    No full text
    The growth of the 5 and 6 year old potted cloned spruces, that receive different amount of magnesium, is investigated during water stress periods in 1989 and 1990. In the two following years, flushing and growth reactions due to watering are studied. Nutrient uptake and clone related differences are part of this investigation. Water stress principally reduces the branch length and the number of the needles. In the two following years, the water stressed spruces flush earlier than the watered spruces. Mg deficiency has little effect on branch growth, but reduces the number of needles considerably. Water stress does not influence the Mg uptake directly. Rewatering after a long water stress period increases the MG contents in the youngest needles, which can be seen as a regreening of the yellowed needles. The continually high growth of the spruces without a braking effect of drougth results in the yellowing of the older needles. Fertilization with magnesium leads to regreening. Clone-specific differences are also recorded. (orig.)SIGLEAvailable from TIB Hannover: RO 2590(114) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekLand Baden-Wuerttemberg, Stuttgart (Germany); Commission of the European Communities (CEC), Luxembourg (Luxembourg)DEGerman

    Schadgas-Ausschlussexperiment bei Fichten am Edelmannshof: Beschreibung der Versuchsanlage und Untersuchungen zum Stoffhaushalt

    No full text
    The Edelmannshof project aimed at studying the effects of long-term excluding gaseous air pollutants from spruce trees (Picea abies Karst.) growing in a remote forest area in Southwest Germany. For a duration of six years, each four 20 years old, healthy looking trees were growing in charcoal filtered air and in ambient air with the help of Open top chambers, four more trees nearby were analysed as non-chamber controls. The data reported here are related to the general design and performance of the experimental plant, and to the basal investigation of mineral cycling in the different treatments. Special focus was on canopy buffering and leaching of nutrients from foliage due to deposition of acidic compounds. A comparison of environmental conditions and of growth parameters in the different treatments showed clearly that naturally stocking trees up to 10 m high can be kept in 10-20% of ambient gaseous pollutant exposure in environments allowing normal growth for several years. By analysing quasi-continuously the relevant fluxes involved in the atmosphere-canopy material exchange, including wet and dry deposition of gases, solutes and particulates, we were able to separate the processes contributing to net throughfall enrichment of waters passing the canopy, i.e. the overall canopy deposition of acidic gases and the resulting leaching of basic cations, above all of magnesium. An initial step of the complex dose-effect relationship leading to a common symptom of forest disease - enhanced supply of sulphur and nitrogen associated with reduced supply of basic cations - has been proven experimentally for the first time with natural vegetation growing in ambient air of a remote forest site. Due to a sufficient supply of basic cations in the soil solution of our test case study, the cations leached from foliage were immediately replaced and a deficiency with needle yellowing symptoms was not observed. Ozone did not show any clear effects on mineral cycling or on leaching rates. The leaching effect observed even at very low SO_2 exposure seems to be triggered by microclimatic conditions favouring material exchange, above all by surface wetness; probably in interaction with co-deposition of NH_3. The decreasing amount of overall sulphur deposition observed during the six years course of the experiment is explained by the effects of regional measures to reduce sulphur emissions from point sources. A corresponding pattern could not be observed during the course of our experiment with respect to nitrogen deposition. (orig.)In einem Waldgebiet, ca. 35 km ostnordoestlich des Ballungsraumes Stuttgart, wurden 8 Open-top Kammern um ca. fuenfundzwanzigjaehrige Fichten (Picea abies Karst.) herum errichtet. In dem als Schadgas-Ausschlussexperiment konzipierten Langzeitversuch wurde ueber einen Zeitraum von sechs Jahren in 4 Kammern Umgebungsluft eingeblasen, die anderen vier erhielten Aktivkohlegereinigte (schadgasarme) Luft. Alle Kammern und 4 freistehende ('Freiland-')Fichten wurden mit einem umfangreichen Instrumentarium zur Messung luftchemischer, klimatologischer und bodenchemischer Faktoren sowie zur Erfassung von Aerosoldepositionen, internen Stoffkreislaeufen und besonders des 'Leachings' versehen. Abschliessend wurde die Biomasse der Versuchsbaeume bestimmt. Stoffkreislauf-Daten konnten damit auf Biomasse bezogen werden. Die vorgestellten Versuchsergebnisse ermoeglichen eine Differenzierung der Prozesse, die an der Veraenderung der Elementfluesse bei der Kronenraumpassage der Niederschlaege und speziell beim Leaching beteiligt sind. Es konnte nachgewiesen werden, dass sich durch die Ausfilterung saeureliebender, wasserloeslicher Gase, speziell von SO_2 im Kronenraum - auch bei geringen Belastungen - ein Leaching basischer Kationen, besonders von Magnesium aus den Nadeln ergibt. Dieser Verlust liess sich exakt beziffern; er kann rasch ausgeglichen werden, wenn im Boden genuegend dieser Ionen verfuegbar sind, andernfalls drohen Engpaesse und Mangelzustaende. Ozon, dessen Konzentration waehrend des Versuches staendig etwas zunahm, hatte keinen Einfluss auf das Leaching. Der Versuch zeigt, dass die in den 80er Jahren erlassenen gesetzlichen Auflagen von Luftreinhaltemassnahmen hilfreich waren. (orig.)SIGLEAvailable from TIB Hannover: RO 2590(163) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekLand Baden-Wuerttemberg, Stuttgart (Germany)DEGerman
    corecore