472 research outputs found
On the robustness of q-expectation values and Renyi entropy
We study the robustness of functionals of probability distributions such as
the R\'enyi and nonadditive S_q entropies, as well as the q-expectation values
under small variations of the distributions. We focus on three important types
of distribution functions, namely (i) continuous bounded (ii) discrete with
finite number of states, and (iii) discrete with infinite number of states. The
physical concept of robustness is contrasted with the mathematically stronger
condition of stability and Lesche-stability for functionals. We explicitly
demonstrate that, in the case of continuous distributions, once unbounded
distributions and those leading to negative entropy are excluded, both Renyi
and nonadditive S_q entropies as well as the q-expectation values are robust.
For the discrete finite case, the Renyi and nonadditive S_q entropies and the
q-expectation values are robust. For the infinite discrete case, where both
Renyi entropy and q-expectations are known to violate Lesche-stability and
stability respectively, we show that one can nevertheless state conditions
which guarantee physical robustness.Comment: 6 pages, to appear in Euro Phys Let
Quantification of systemic risk from overlapping portfolios in the financial system
Financial markets create endogenous systemic risk, the risk that a substantial fraction of the system
ceases to function and collapses. Systemic risk can propagate through different mechanisms and channels
of contagion. One important form of financial contagion arises from indirect interconnections between
financial institutions mediated by financial markets. This indirect interconnection occurs when financial
institutions invest in common assets and is referred to as overlapping portfolios. In this work we quantify systemic risk from indirect interconnections between financial institutions. Complete information of
security holdings of major Mexican financial intermediaries and the ability to uniquely identify securities
in their portfolios, allows us to represent the Mexican financial system as a bipartite network of securities
and financial institutions. This makes it possible to quantify systemic risk arising from overlapping portfolios. We show that focusing only on direct interbank exposures underestimates total systemic risk levels
by up to 50% under the assumptions of the model. By representing the financial system as a multi-layer
network of direct interbank exposures (default contagion) and indirect external exposures (overlapping
portfolios) we estimate the mutual influence of different channels of contagion. The method presented
here is the first quantification of systemic risk on national scales that includes overlapping portfolio
litsift: Automated Text Categorization in Bibliographic Search
In bioinformatics there exist research topics that cannot be uniquely characterized by a set of key words because relevant key words are (i) also heavily used in other contexts and (ii) often omitted in relevant documents because the context is clear to the target audience. Information retrieval interfaces such as entrez/Pubmed produce either low precision or low recall in this case. To yield a high recall at a reasonable precision, the results of a broad information retrieval search have to be filtered to remove irrelevant documents. We use automated text categorization for this purpose. In this study we use the topic of conserved secondary RNA structures in viral genomes as running example. Pubmed result sets for two virus groups, Picornaviridae and Flaviviridae, have been manually labeled by human experts. We
evaluated various classifiers from the Weka toolkit together with different feature selection methods to assess whether classifiers trained on documents dedicated to one virus group can be successfully applied to filter literature on other virus groups. Our results indicate that in this domain a bibliographic search tool trained on a reference corpus may significantly reduce the amount of time needed for extensive literature recherches
Conserved RNA secondary structures in Flaviviridae genomes
Presented here is a comprehensive computational survey of evolutionarily conserved secondary structure motifs in the genomic RNAs of the family Flaviviridae. This virus family consists of the three genera Flavivirus, Pestivirus and Hepacivirus and the group of GB virus C/hepatitis G virus with a currently uncertain taxonomic classification. Based on the control of replication and translation, two subgroups were considered separately: the genus Flavivirus, with its type I cap structure at the 5′ untranslated region (UTR) and a highly structured 3′ UTR, and the remaining three groups, which exhibit translation control by means of an internal ribosomal entry site (IRES) in the 5′ UTR and a much shorter less-structured 3′ UTR. The main findings of this survey are strong hints for the possibility of genome cyclization in hepatitis C virus and GB virus C/hepatitis G virus in addition to the flaviviruses; a surprisingly large number of conserved RNA motifs in the coding regions; and a lower level of detailed structural conservation in the IRES and 3′ UTR motifs than reported in the literature. An electronic atlas organizes the information on the more than 150 conserved, and therefore putatively functional, RNA secondary structure elements
Peer-review in a world with rational scientists: Toward selection of the average
One of the virtues of peer review is that it provides a self-regulating
selection mechanism for scientific work, papers and projects. Peer review as a
selection mechanism is hard to evaluate in terms of its efficiency. Serious
efforts to understand its strengths and weaknesses have not yet lead to clear
answers. In theory peer review works if the involved parties (editors and
referees) conform to a set of requirements, such as love for high quality
science, objectiveness, and absence of biases, nepotism, friend and clique
networks, selfishness, etc. If these requirements are violated, what is the
effect on the selection of high quality work? We study this question with a
simple agent based model. In particular we are interested in the effects of
rational referees, who might not have any incentive to see high quality work
other than their own published or promoted. We find that a small fraction of
incorrect (selfish or rational) referees can drastically reduce the quality of
the published (accepted) scientific standard. We quantify the fraction for
which peer review will no longer select better than pure chance. Decline of
quality of accepted scientific work is shown as a function of the fraction of
rational and unqualified referees. We show how a simple quality-increasing
policy of e.g. a journal can lead to a loss in overall scientific quality, and
how mutual support-networks of authors and referees deteriorate the system.Comment: 5 pages 4 figure
Confinement and Topological Charge in the Abelian Gauge of QCD
We study the relation between instantons and monopoles in the abelian gauge.
First, we investigate the monopole in the multi-instanton solution in the
continuum Yang-Mills theory using the Polyakov gauge. At a large instanton
density, the monopole trajectory becomes highly complicated, which can be
regarded as a signal of monopole condensation. Second, we study instantons and
monopoles in the SU(2) lattice gauge theory both in the maximally abelian (MA)
gauge and in the Polyakov gauge. Using the lattice, we find
monopole dominance for instantons in the confinement phase even at finite
temperatures. A linear-type correlation is found between the total
monopole-loop length and the integral of the absolute value of the topological
density (the total number of instantons and anti-instantons) in the MA gauge.
We conjecture that instantons enhance the monopole-loop length and promote
monopole condensation.Comment: 3 pages, LaTeX, Talk presented at LATTICE96(topology
Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes
By performing a comprehensive study on 1832 segments of 1212 complete genomes
of viruses, we show that in viral genomes the hairpin structures of
thermodynamically predicted RNA secondary structures are more abundant than
expected under a simple random null hypothesis. The detected hairpin structures
of RNA secondary structures are present both in coding and in noncoding regions
for the four groups of viruses categorized as dsDNA, dsRNA, ssDNA and ssRNA.
For all groups hairpin structures of RNA secondary structures are detected more
frequently than expected for a random null hypothesis in noncoding rather than
in coding regions. However, potential RNA secondary structures are also present
in coding regions of dsDNA group. In fact we detect evolutionary conserved RNA
secondary structures in conserved coding and noncoding regions of a large set
of complete genomes of dsDNA herpesviruses.Comment: 9 pages, 2 figure
Lack of consensus in social systems
We propose an exactly solvable model for the dynamics of voters in a
two-party system. The opinion formation process is modeled on a random network
of agents. The dynamical nature of interpersonal relations is also reflected in
the model, as the connections in the network evolve with the dynamics of the
voters. In the infinite time limit, an exact solution predicts the emergence of
consensus, for arbitrary initial conditions. However, before consensus is
reached, two different metastable states can persist for exponentially long
times. One state reflects a perfect balancing of opinions, the other reflects a
completely static situation. An estimate of the associated lifetimes suggests
that lack of consensus is typical for large systems.Comment: 4 pages, 6 figures, submitted to Phys. Rev. Let
Simple model for 1/f noise
We present a simple stochastic mechanism which generates pulse trains
exhibiting a power law distribution of the pulse intervals and a
power spectrum over several decades at low frequencies with close to
one. The essential ingredient of our model is a fluctuating threshold which
performs a Brownian motion. Whenever an increasing potential hits the
threshold, is reset to the origin and a pulse is emitted. We show that
if increases linearly in time, the pulse intervals can be approximated
by a random walk with multiplicative noise. Our model agrees with recent
experiments in neurobiology and explains the high interpulse interval
variability and the occurrence of noise observed in cortical
neurons and earthquake data.Comment: 4 pages, 4 figure
Complete diagrammatics of the single ring theorem
Using diagrammatic techniques, we provide explicit functional relations
between the cumulant generating functions for the biunitarily invariant
ensembles in the limit of large size of matrices. The formalism allows to map
two distinct areas of free random variables: Hermitian positive definite
operators and non-normal R-diagonal operators. We also rederive the
Haagerup-Larsen theorem and show how its recent extension to the eigenvector
correlation function appears naturally within this approach.Comment: 18 pages, 6 figures, version accepted for publicatio
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