Vitamin A In Veterinary Medicine

Veterinarians now have available vitamin preparations which are intended for use as specific drugs in the prophylaxis and therapy of disease processes. Use of these products requires knowledge of indications for their use in rational therapy. This article is intended to aid in presenting this information for vitamin A

Giant synovial cell sarcoma of the thorax in a 46-year-old man: a case report

Background:Although synovial cell sarcoma is a common tumor of the extremities, its occurrence in the thorax has been less frequently documented. Case Presentation: A 46-year-old Pakistani man presented with a 2 month history of progressively increasing cough and left lower chest pain. Initial evaluation was done using a chest x-ray, the Patient was found to have a large mass involving the lower portion of the left chest. A computed tomography scan was performed next which showed a large mass involving the left chest wall with invasion into the pericardium and left hemidiaphragm. En bloc surgical resection of the tumor was undertaken. Final pathology showed synovial cell sarcoma of the thorax. At one-year follow-up, the Patient has shown no recurrence of the disease. Conclusions: We have described a rare case of a large synovial cell sarcoma of the thorax. Surgical resection appears an appropriate modus operandi for managing giant synovial cell sarcomas of the thorax. However, there is a need to clearly define post-operative strategies for cases with extensive involvement of surrounding structures

Identification of Ventricular Tachycardia Using Intracavitary Ventricular Electrograms: Analysis of Time and Frequency Domain Patterns

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74961/1/j.1540-8159.1988.tb06279.x.pd

Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium

The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epithelial cells. TLR3 was constitutively expressed; however, RIG-I and MDA5 were inducible by 8–12 h following rhinovirus infection. Bronchial epithelial tissue from normal volunteers challenged with rhinovirus in vivo exhibited low levels of RIG-I and MDA5 that were increased at day 4 post infection. Inhibition of TLR3, RIG-I and MDA5 by siRNA reduced innate cytokine mRNA, and increased rhinovirus replication. Inhibition of TLR3 and TRIF using siRNA reduced rhinovirus induced RNA helicases. Furthermore, IFNAR1 deficient mice exhibited RIG-I and MDA5 induction early during RV1B infection in an interferon independent manner. Hence anti-viral defense within bronchial epithelium requires co-ordinated recognition of rhinovirus infection, initially via TLR3/TRIF and later via inducible RNA helicases

Veterinary Public Health

Many an individual recently assigned to active duty with United States Army Veterinary Corps has expressed surprise upon finding he was to learn federal specifications covering such things as fresh shrimp, lard substitute, creamery butter, eggs; in fact all food products of animal origin. Yet where would a more logical assignment to determine soundness, contamination, and fitness for consumption of such products fall? All of his special senses and thought processes are trained in skillful application of scientific facts to detection of gross and microscopic deviations from normal in animal tissues during life and at post mortem, diagnosis of their causative agents, and methods of preventing their occurrence.</p

Vitamin A In Veterinary Medicine

Veterinarians now have available vitamin preparations which are intended for use as specific drugs in the prophylaxis and therapy of disease processes. Use of these products requires knowledge of indications for their use in rational therapy. This article is intended to aid in presenting this information for vitamin A.</p