Solubilities of gases in cycloethers. The solubility of 13 nonpolar gases in 2, 5-dimethyltetrahydrofuran at 273.15 to 303.15¿K and 101.32¿kPa

The solubilities of gases in liquids are interesting, not only from a practical point of view, but also because they provide a rigorous touchstone to test the structural models on the liquid state. In this work the solubilities of 13 nonpolar gases, He, Ne, Ar, Kr, Xe, H2, D2, N2, CH4, C2H4, C2H6, CF4, and SF6, in 2, 5-dimethyltetrahydrofuran at five temperatures between (273.15 and 303.15) K and 101.32 kPa partial pressure of gas were measured and the associated thermodynamic functions were calculated. Correlation of data has been made and the capacity of prediction of several typical molecular models of liquids, namely, SPT model, perturbation theory, UNIFAC and COSMO-RS, specifically applied to gas solubilities, has been checked

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe

Solubility of non-polar gases in anisol, at 283.15 to 303.15 °K

Solubility measurements of several non-polar gases (He, Ne, Ar, Kr, D2, CH4, CF4, and SF6) in anisol at 283.15 to 303.15 K and a partial pressure of gas of 1 atmosphere are reported. Gibbs free energy, enthalpy and entropy of solution at 298.15 K and 1 atm partial pressure of gas are evaluated. Using the scaled-particle theory, Lennard-Jones (6, 12) pair-potential parameters for anisol were also determined