14 research outputs found

    Pengembangan Alat Gerak Jatuh Bebas Sebagai Media Pembelajaran Konsep Gerak Jatuh Bebas

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    This research development aimed to produce a Free Fall Motion device and LKS that can be used as an media of physics learning.The model was adapted from Sadiman which included phases need analysis, formulate learning objective, materials, develop evaluation instruments, prepare draft of media, validation from expert, experiments, and final product. Results of this study produced the Free Fall Motion device which able to measure the time of falling object automatically, vary the height of falling objects, release the falling objects automatically, and investigate influence of mass toward the time of falling object use sound sensor.The product which was developed had been tested expertly testing design and materials. Results from experiments showed that device used very attractive, easy to use, and very useful. The learning outcomes of students after using the device showed that 100% had reached KKM so that the developed product was highly effective and acceptable to be used as a learning media.Penelitian ini bertujuan menghasilkan alat Gerak Jatuh Bebas beserta LKS yang dapat digunakan sebagai media pembelajaran fisika. Model pengembangan diadaptasi dari Sadiman yang meliputi tahapan analisis kebutuhan, merumuskan tujuan pembelajaran, butir-butir materi, menyusun instrumen evaluasi, menyusun draft media, validasi ahli, uji coba, dan produk akhir. Hasil penelitian berupa alat Gerak Jatuh Bebas yang mampu mengukur waktu jatuh benda secara otomatis, memvariasikan ketinggian jatuh benda, pelepasan benda jatuh secara otomatis, dan dapat menyelidiki pengaruh massa benda terhadap waktu jatuh dengan memanfaatkan sensor suara. Produk yang dikembangkan telah diuji desain dan materi. Hasil uji coba menyatakan bahwa alat yang digunakan sangat menarik, mudah digunakan, dan sangat bermanfaat. Hasil belajar siswa setelah menggunakan alat ini 100% mencapai batas KKM sehingga produk yang dikembangkan sangat efektif dan layak digunakan sebagai media pembelajaran

    Pengembangan Multimedia Interaktif Tutorial Menggunakan Pendekatan Kontekstual

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    The results of needed analysis is known that Learning activities of students generally rely on print books as instructional media. It make the students feel bored and less interested and also feel difficult on physics subject. Consider the problem, researchers developed an multimedia interactive tutorial using a contextual approached that feasible and effective. Development procedures include: analyzing of needed, formulating learning goals, formulating the item of subject, formulating successfull measurement, drafting, validating, testing and revising, and also the final product. Products have been developed tested by the experts and tested on students. Experimental results show that the products used are very attractive, very easy to use, and very useful. The results of learning students stated that the multimedia interactive tutorial that have been developed is effective and feasible to be used as a instructional media.Hasil analisis kebutuhan diketahui bahwa Kegiatan belajar siswa umumnya hanya mengandalkan buku cetak sebagai media pembelajaran. Hal tersebut membuat siswa merasa bosan dan kurang tertarik serta mengalami kesulitan terhadap pelajaran fisika. Mempertimbangkan masalah tersebut, peneliti mengembangkan multimedia interaktif tutorial dengan menggunakan pendekatan kontekstual yang layak dan efektif. Prosedur pengembangan meliputi: analisis kebutuhan, merumuskan tujuan pembelajaran, merumuskan butir-butir materi, Perumusan alat ukur keberhasilan, menyusun naskah, melakukan validasi, melakukan uji coba dan revisi, dan produk akhir. Produk yang dikembangkan telah diuji oleh ahli dan diujicobakan pada siswa. Hasil uji coba menunjukkan bahwa produk yang digunakan sangat menarik, sangat mudah digunakan, dan sangat bermanfaat. Hasil belajar siswa menyatakan bahwa multimedia interaktif tutorial yang dikembangkan efektif dan layak digunakan sebagai media pembelajaran

    Pemanfaatan Media Tik Tutorial Sebagai Komplemen Demonstrasi Pada Pembelajaran Alat Ukur Di SMP

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    The purposes of this study were to determine the increasing of cognitive learning outcomes of students and to describe the Science Process Skills (sps), the character, the activities, and students attitudes toward the use of ICT tutorial media as a demonstration complement on the learning of measurement tools. This research was conducted at the first semester of the academic year 2013/2014 at the Junior High School 1 Seputih Agung, Central Lampung and the design of this research was One-Shot Case Study. The results of this research showed that there is an increasing in cognitive learning outcomes of students, it can build the KPS of students, it can build the character of the students, it can increase the activities of the students, and it can increase a positive attitudes of the students.Penelitian ini bertujuan untuk: mengetahui peningkatan hasil belajar ranah kognitif, mendeskripsikan KPS, karakter, aktivitas dan sikap siswa terhadap pemanfaatan media TIK tutorial sebagai komplemen demonstrasi pada pembelajaran alat ukur. Penelitian ini dilakukan di semester ganjil pada tahun ajaran 2013/2014 di SMP Negeri 1 Seputih Agung, Lampung Tengah dan desain penelitian yang digunakan adalah One-Shot Case Study. Hasil penelitian ini adalah terdapat peningkatan hasil belajar ranah kognitif siswa, dapat membangun KPS siswa, dapat menumbuhkan karakter siswa, dapat meningkatkan aktivitas belajar siswa dan membangun sikap positif siswa

    Studi Perbandingan Hasil Belajar Fisika Antara Penggunaan Gambar Bergerak Dengan Gambar Statis

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    The purposes of this research were to determine the difference of learning outcome used dynamic images with static images and describe each of learning outcome. The samples in this research were students of class X in SMA Negeri 3 Kotabumi. The research was conducted used the one-group pretest-posttest design. Data were tested with N-gain analysis, normality test, homogeneity test and Mann-Whitney test. The results of Mann-Whitney test, asymp.sig value was 0.014, it can be stated that the average N-gain of learning outcomes used dynamic image is higher than the average N-gain of learning outcome of static image. Based on these result, there was the difference in learning outcome between two experimental classes. Beside that, there was an increasing of student's learning outcome by medium category which used dynamic image as well as static image.Tujuan penelitian ini adalah untuk mengetahui perbedaan hasil belajar berbantuan gambar bergerak dengan gambar statis dan mendiskripsikan masing-masing hasil belajar. Sampel penelitian ini adalah siswa kelas X SMA Negeri 3 Kotabumi. Penelitian dilakukan menggunakan one-group pretest-posttest design. Data diuji dengan analisis N-gain, uji normalitas, uji homogenitas dan uji Mann-Whitney. Hasil dari uji Mann-Whitney, nilai asymp. sig. yaitu 0,014, maka dapat dinyatakan rata-rata N-gain hasil belajar berbantuan gambar bergerak lebih tinggi dibandingkan dengan rata-rata N-gain hasil belajar berbantuan gambar statis. Sehingga dapat dikatakan, terdapat perbedaan hasil belajar antara kedua kelas eksperimen. Seain itu, hasil belajar siswa berbantuan gambar bergerak, maupun gambar statis mengalami peningkatan dengan kategori sedang

    Pengembangan Multimedia Interaktif Model Tutorial

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    This developmental research was intended to make an interactiveΓ‚ multimedia tutorial model by using Microsoft PowerPoint for SMP/MTs on theΓ‚ static and dynamic electricity subjects that contain materials, interactiveΓ‚ animation, virtual labs, exercises, and competence test. This design ofΓ‚ evelopmental research modified the process of the instructional mediaΓ‚ development developed by Sadiman, et al. With the stages of work procedureΓ‚ that comprise needs analysis, objectives, materials, synopsis, initial script,Γ‚ prototype production, evaluation consisting of three phases, namely the materialΓ‚ expert test, the design expert test, and one on one expert test. This also includesΓ‚ revision, final script, trials, and final program. The result of one on one testΓ‚ stating that this interactive multimedia has an interesting quality, easy to use,and it is very useful. It is also the same with the result of field test that also hasΓ‚ an interesting quality, easy to use, and it is very useful also.From the result of theΓ‚ field test can be concluded that this interactive multimedia is very effective to beused as a learning resource.

    Perbandingan Aktivitas Dan Hasil Belajar Menggunakan Penilaian Otentik Dengan Penilaian Konvensional

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    Learning activity is a series of physical and mental activity. To obtain a good learning result the physical and mental activity must be coordinated. The better the activities undertaken by the students then students will understand and master the subject matter presented by the teacher, so that students will gain maximum learning results. The aim of this study was to determine the activity and higher student outcomes between classes using authentic assessment models with conventional assessment models. The population in this study were high school students of class VII in Utama 2 Bandar Lampung while the sample is class X1 and X4 semester Utama 2 Bandar Lampung school, sampling was take using Purposive Sampling technique. Variable was consist of two independent variables and two dependent variables, Authentic Assessment, Conventional Assessment, Activity, and Learning Outcomes. Different test using Independent Sample t-Test showed H0 is rejected. The results showed that learning activities for classroom use authentic assessment is higher than the class that uses conventional assessment, while learning outcomes did not show any difference.Aktivitas belajar adalah serangkaian kegiatan fisik dan mental. Untuk memperoleh hasil belajar yang baik maka aktivitas fisik dan mental harus terkoordinasi dengan baik. Semakin baik aktivitas yang dilakukan oleh siswa maka siswa akan semakin memahami dan meguasai materi pelajaran yang disampaikan oleh guru, sehingga siswa akan memperoleh hasil belajar yang maksimal. Penelitian ini bertujuan untuk mengetahui Aktivitas dan hasil siswa yang lebih tinggi antara kelas yang menggunakan model penilaian otentik dengan model penilaian konvensional. Populasi pada penelitian ini adalah siswa kelas VII di SMA Utama 2 Bandar Lampung sedangkan sampelnya adalah siswa kelas X1 dan X4 semester ganjil SMA Utama 2 Bandar Lampung, pengambilan sampel dilakukan dengan teknik Purposive Sampling. Variabel terdiri dari dua variabel bebas dan dua variabel terikat. Uji beda menggunakan uji Independent Sample t-Test menunjukkan H0 ditolak. Hasil penelitian memperlihatkan aktivitas belajar untuk kelas yang menggunakan penilaian otentik lebih tinggi dari kelas yang menggunakan penilaian konvensional, sedangkan hasil belajar tidak menunjukkan adanya perbedaan

    Perbandingan Kps Dan Hasil Belajar Menggunakan Metode Eksperimen Laboratorium Nyata Dan Maya

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    Experiments need to be conducted in order to develop scientific thinking in a systematic, objective, critical and rational and training Science Process Skills (SPS) students but the experimental method is rarely done in schools due to lack of lab equipment in the lab. The purpose of this research was to determine differences in SPS and student learning achievement caused by the use of experimental methods and to investigate the interaction between the use of experimental methods and the prior knowledge when viewed from the acquisition of SPS score and the learning achievement of student. The research design was factorial design and hypothesis testing using univariate tests. Mean of student SPS scores who experiment in virtual laboratory was 18.6 and 71.4 for their learning achievement. KPS score who experiment in real laboratory was 17.7 and 60.2 for their learning achievement. Univariate test results showed no effect of the experimental method to the SPS and t learning achievement of students. Obtained a significant interaction between the experimental method and prior knowledge when viewed from KPS score and learning achievement

    The Improving of Methylprednisolone Palmitate Potency After Incorporated with Liposome - an Antiinflammation Study in Culture of Mice\u27s Splenocytes

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    Glucocorticoid has been used as an antiinflammatory and immuno-suppresive drug. Longterm utilisation at high dose of glucocorticoid is associated with serious side effects. In recent years, many attempts have been performed in searching the appropiate vehicles to deliver the drug directly into the target organ or the receptor. By incorporating the drug into its vehicle such as liposome, the systemic side effect can be minimized. Purwaningsih et al has successfully synthetized a novel preparation of liposome methylprednisolone palmitate (L-MPLP). The aim of the study was to learn the pharmacological effect of L-MPLP, especially on antiinflammatory effect of this novel preparation, compared with the standard methylprednisolone (MPL). The parameter was the potency of L-MPLP in reducing gamma-interferon production in T-lymphocyte culture after stimulation with concanavalin A in vitro as well as in vivo. Gamma-interferon was assayed by ELISA method. The reduction of gamma interferon, in vivo, after the administration of L-MPLP at the dose of 2,8 and 16 mg/kgBW respectively, showed significant difference than a control group, while MPL did not. The addition of both L-MPLP and MPL in in vitro culture at the concentration of 5.10-3, 5.10-2 and 5.10-1 mM have proved to suppress the gammainterferon production, where the suppression of L-MPLP was more effective than MPL, significantly

    ΠšΡƒΡ€ΠΊΡƒΠΌΠΈΠ½ сниТаСт ΠΏΡ€ΠΎΠ»ΠΈΡ„Π΅Ρ€Π°Ρ†ΠΈΡŽ ΠΊΠ»Π΅Ρ‚ΠΎΠΊ Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Ρ‡Π΅Ρ€Π΅Π· Π±Π΅Π»ΠΊΠΈ RASSF1A, Bax ΠΈ caspase-3

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    Background. Curcumin is a polyphenol that has pharmacological activity that can inhibit tumor cell growth and induce apoptosis through various mechanisms. However, the specifc mechanism of curcumin cytotoxicity remains controversial because of many anti- and pro-apoptotic signaling pathways in various cell types.This study aims to examine the relationship among curcumin on RASSF1A, Bax protein levels, and caspase-3 activity in supporting the apoptotic mechanism in CSA03 breast cancer cells.Material and Methods. Curcumin administration to cancer cells is based on differences in dosage with 24-hour incubation. Cytotoxicity after curcumin administration was determined using MTS. RASSF1A and Bax protein levels were tested through ELISA. Caspase-3 activity was used to determine apoptosis and was tested using fow cytometry.Results. The results indicated that curcumin had a cytotoxicity effect of 40.85 Β΅g/mL. At concentrations of 40 Β΅g/mL and 50 Β΅g/mL, curcumin increases levels of protein RASSF1A (βˆ† = 26.53% and 47.35%, respectively), Bax (βˆ† = 48.79% and 386.15%), and caspase-3 (βˆ† = 1,678.51% and 1,871.889%) signifcantly.Conclusions. Curcumin exhibits anti-proliferative activity and apoptotic (Caspase-3) effects through activation of RASSF1A and Bax.Β ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ. ΠšΡƒΡ€ΠΊΡƒΠΌΠΈΠ½ прСдставляСт собой ΠΏΠΎΠ»ΠΈΡ„Π΅Π½ΠΎΠ», ΠΎΠ±Π»Π°Π΄Π°ΡŽΡ‰ΠΈΠΉ фармакологичСской Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒΡŽ, которая ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈΠ½Π³ΠΈΠ±ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ рост ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ΠΈ Π²Ρ‹Π·Ρ‹Π²Π°Ρ‚ΡŒ Π°ΠΏΠΎΠΏΡ‚ΠΎΠ· с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΠΎΠ². Однако ΠΊΠΎΠ½ΠΊΡ€Π΅Ρ‚Π½Ρ‹ΠΉ ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌ цитотоксичности ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° остаСтся спорным ΠΈΠ·-Π·Π° мноТСства Π°Π½Ρ‚ΠΈ- ΠΈ проапоптотичСских ΡΠΈΠ³Π½Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΡƒΡ‚Π΅ΠΉ Π² Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… Ρ‚ΠΈΠΏΠ°Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ.ЦСлью исслСдования явилось ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ взаимосвязи ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° с уровнями Π±Π΅Π»ΠΊΠ° RASSF1A, Bax ΠΈ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒΡŽ каспазы-3 Π² ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΠ΅ ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΠ° Π°ΠΏΠΎΠΏΡ‚ΠΎΠ·Π° Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ CSA03.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π» ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Π’Π²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° Π² Ρ€Π°ΠΊΠΎΠ²Ρ‹Π΅ ΠΊΠ»Π΅Ρ‚ΠΊΠΈ основано Π½Π° различиях Π² Π΄ΠΎΠ·ΠΈΡ€ΠΎΠ²ΠΊΠ΅ ΠΏΡ€ΠΈ 24-часовой ΠΈΠ½ΠΊΡƒΠ±Π°Ρ†ΠΈΠΈ. Π¦ΠΈΡ‚ΠΎΡ‚ΠΎΠΊΡΠΈΡ‡Π½ΠΎΡΡ‚ΡŒ послС ввСдСния ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° опрСдСляли с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ MTS. Π£Ρ€ΠΎΠ²Π½ΠΈ Π±Π΅Π»ΠΊΠΎΠ² RASSF1A ΠΈ Bax тСстировали с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ ELISA. ΠΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ каспазы-3 использовали для опрСдСлСния Π°ΠΏΠΎΠΏΡ‚ΠΎΠ·Π° ΠΈ тСстировали с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ ΠΏΡ€ΠΎΡ‚ΠΎΡ‡Π½ΠΎΠΉ Ρ†ΠΈΡ‚ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΠΈ. БтатистичСская ΠΎΠ±Ρ€Π°Π±ΠΎΡ‚ΠΊΠ° Π΄Π°Π½Π½Ρ‹Ρ… ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡŒ с использованиСм ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ Statistical Program for Social Science (SPSS) вСрсии 20.0 для Windows. ΠŸΡ€ΠΎΠ²Π΅Ρ€ΠΊΠ° Π³ΠΈΠΏΠΎΡ‚Π΅Π· Π²Ρ‹ΠΏΠΎΠ»Π½ΡΠ»Π°ΡΡŒ с использованиСм нСпарамСтричСского числСнного ΡΡ€Π°Π²Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ тСста ΠΏΡ€ΠΎΠ²Π΅Ρ€ΠΊΠΈ Π³ΠΈΠΏΠΎΡ‚Π΅Π·. Для ΠΎΡ†Π΅Π½ΠΊΠΈ Ρ€Π°Π·Π½ΠΈΡ†Ρ‹ ΠΌΠ΅ΠΆΠ΄Ρƒ >2 Π³Ρ€ΡƒΠΏΠΏΠ°ΠΌΠΈ Π½Π΅ΠΏΠ°Ρ€Π½Ρ‹Ρ… ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†ΠΈΠΉ использовали нСпарамСтричСский ΠΊΡ€ΠΈΡ‚Π΅Ρ€ΠΈΠΉ ΠšΡ€ΡƒΡΠΊΠ°Π»Π°β€“Π£ΠΎΠ»Π»ΠΈΡΠ°, Π° для ΠΎΡ†Π΅Π½ΠΊΠΈ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΠΉ Ρ€Π°Π·Π½ΠΈΡ†Ρ‹ Π² Π΄Π²ΡƒΡ… Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ апостСриорный Π°Π½Π°Π»ΠΈΠ· ΠœΠ°Π½Π½Π°β€“Π£ΠΈΡ‚Π½ΠΈ.Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Показано, Ρ‡Ρ‚ΠΎ цитотоксичСский эффСкт ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° составил 40,85 ΠΌΠΊΠ³/ΠΌΠ». Π’ концСнтрациях 40 ΠΌΠΊΠ³/ΠΌΠ» ΠΈ 50 ΠΌΠΊΠ³/ΠΌΠ» ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½ ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΠ²Π°Π΅Ρ‚ ΡƒΡ€ΠΎΠ²Π½ΠΈ Π±Π΅Π»ΠΊΠ° RASSF1A (βˆ† = 26,53 % ΠΈ 47,35 %, соотвСтствСнно), Bax (βˆ† = 48,79 % ΠΈ 386,15 %) ΠΈ каспазы-3 (βˆ† = 1678,51 % ΠΈ 1871,889 %).Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. Π’Π²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΊΡƒΡ€ΠΊΡƒΠΌΠΈΠ½Π° Π² ΠΊΠ»Π΅Ρ‚ΠΊΠΈ CSA03 эффСктивно ΡƒΠΌΠ΅Π½ΡŒΡˆΠ°Π»ΠΎ рост ΠΊΠ»Π΅Ρ‚ΠΎΠΊ Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ in vitro Π·Π° счСт Ρ€Π΅Π°ΠΊΡ‚ΠΈΠ²Π°Ρ†ΠΈΠΈ RASSF1A Π² качСствС Π³Π΅Π½Π°-супрСссора ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ ΠΈ ΠΏΠΎΠ²Ρ‹ΡˆΠ°Π»ΠΎ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π±Π΅Π»ΠΊΠ° Bax Π² качСствС ΠΈΠ½Π΄ΡƒΠΊΡ†ΠΈΠΈ Π°ΠΏΠΎΠΏΡ‚ΠΎΠ·Π° (caspase-3).
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