1,450 research outputs found

    Oikos nomos Vs. oikos logos? Towards the alliance between business management and environmental sustainability

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    Environmental sustainability is a topic that is increasingly becoming popular and companies are not excluded from this phenomenon. On the contrary, their responsibility towards environment is increasingly in the public eye, so that the same companies pay more and more attention to communicating their commitment to all stakeholders in order to improve their image and reputation. Furthermore, from a scientific point of view, a growing array of studies also investigates how to measure sustainability with the aim of defining more accurate indicators of the environmental impact generated by companies. This work has a threefold objective: 1) highlighting firstly the compatibility between the companies’ activities and green strategies through the analysis of those studies that demonstrate the benefits of implementing eco-sustainable practices; 2) describing the approach actually implemented by the companies; 3) description of the phenomenon of greenwashing that is a kind of communication through which some companies try to appear eco-sustainable, even though they are not.. In the final part of the work some cases of greenwashing are exposed, specifying the negative consequences they have sparked. The relationship between ecology and economics is, indeed, not contrasting but, on the contrary, strongly symbiotic, from the etymological origin of the two terms to the positive effects produced by green strategies, as demonstrated by many studies in literature

    Optical properties of V2O3 in its whole phase diagram

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    Vanadium sesquioxide V2O3 is considered a textbook example of Mott-Hubbard physics. In this paper we present an extended optical study of its whole temperature/doping phase diagram as obtained by doping the pure material with M=Cr or Ti atoms (V1-xMx)2O3. We reveal that its thermodynamically stable metallic and insulating phases, although macroscopically equivalent, show very different low-energy electrodynamics. The Cr and Ti doping drastically change both the antiferromagnetic gap and the paramagnetic metallic properties. A slight chromium content induces a mesoscopic electronic phase separation, while the pure compound is characterized by short-lived quasiparticles at high temperature. This study thus provides a new comprehensive scenario of the Mott-Hubbard physics in the prototype compound V2O3

    Regulation of NFKB through the nuclear processing of p105 (NFKB1) in Epstein-Barr Virus immortalized B cell lines.

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    Transcription factors of the NF-ÎșB/Rel family are retained in the cytoplasm as inactive complexes through association with IÎșB inhibitory proteins. Several NF-ÎșB activators induce the proteolysis of IÎșB proteins, which results in the nuclear translocation and DNA binding of NF-ÎșB complexes. Here, we report a novel mechanism of NF-ÎșB regulation mediated by p105 (NF-ÎșB1) precursor of p50 directly at the nuclear level. In Epstein- Barr virus-immortalized B cells, p105 was found in the nucleus, where it was complexed with p65. In concomitance with NF-ÎșB activation, mitomycin C induced the processing of p105 to p50 in the nucleus, while it did not affect the steady-state protein levels of IÎșBα and p105 in the cytoplasm. Differently, phorbol 12-myristate 13-acetate induced a significant proteolysis of both IÎșBα and p105 in the cytoplasm, while it did not affect the protein level of p105 in the nucleus. These results suggest that in Epstein-Barr virus-positive B cell lines the nuclear processing of p105 can contribute to NF-ÎșB activation in response to specific signaling molecules, such as DNA-damaging agents

    Electrodynamics near the Metal-to-Insulator Transition in V3O5

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    The electrodynamics near the metal-to-insulator transitions (MIT) induced, in V3O5 single crystals, by both temperature (T) and pressure (P) has been studied by infrared spectroscopy. The T- and P-dependence of the optical conductivity may be explained within a polaronic scenario. The insulating phase at ambient T and P corresponds to strongly localized small polarons. Meanwhile the T-induced metallic phase at ambient pressure is related to a liquid of polarons showing incoherent dc transport, in the P-induced metallic phase at room T strongly localized polarons coexist with partially delocalized ones. The electronic spectral weight is almost recovered, in both the T and P induced metallization processes, on an energy scale of 1 eV, thus supporting the key-role of electron-lattice interaction in the V3O5 metal-to-insulator transition.Comment: 7 pages, 5 figure

    Mediterranean Diet in Developmental Age: A Narrative Review of Current Evidences and Research Gaps

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    Numerous studies in recent decades have shown that Mediterranean diet (MD) can reduce the risk of developing obesity in pediatric patients. The current narrative review summarizes recent evidence regarding the impact of MD across the different stages of child development, starting from fetal development, analyzing breastfeeding and weaning, through childhood up to adolescence, highlighting the gaps in knowledge for each age group. A literature search covering evidence published between 1 January 2000 and 1 March 2022 and concerning children only was conducted using multiple keywords and standardized terminology in PubMed database. A lack of scientific evidence about MD adherence concerns the age group undergoing weaning, thus between 6 months and one year of life. In the other age groups, adherence to MD and its beneficial effects in terms of obesity prevention has been extensively investigated, however, there are still few studies that correlate this dietary style with the incidence of non-communicable diseases. Furthermore, research on multi-intervention strategy should be implemented, especially regarding the role of education of children and families in taking up this healthy dietary style

    A combined experimental and computational study of the pressure dependence of the vibrational spectrum of solid picene C_22H_14

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    We present high-quality optical data and density functional perturbation theory calculations for the vibrational spectrum of solid picene (C22_{22}H14_{14}) under pressure up to 8 GPa. First-principles calculations reproduce with a remarkable accuracy the pressure effects on both frequency and intensities of the phonon peaks experimentally observed . Through a detailed analysis of the phonon eigenvectors, We use the projection on molecular eigenmodes to unambiguously fit the experimental spectra, resolving complicated spectral structures, in a system with hundreds of phonon modes. With these projections, we can also quantify the loss of molecular character under pressure. Our results indicate that picene, despite a \sim 20 % compression of the unit cell, remains substantially a molecular solid up to 8 GPa, with phonon modes displaying a smooth and uniform hardening with pressure. The Grueneisen parameter of the 1380 cm^{-1} a_1 Raman peak (Îłp=0.1\gamma_p=0.1) is much lower than the effective value (Îłd=0.8\gamma_d=0.8) due to K doping. This is an indication that the phonon softening in K doped samples is mainly due to charge transfer and electron-phonon coupling.Comment: Replaced with final version (PRB

    An NF-kB site in the 5'-untraslated leader region of the Human Immunodeficiency virus type 1 enhances the viral expression in response to NF-kB-activating stimuli.

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    The 5'-untranslated leader region of human immunodeficiency virus, type 1 (HIV-1), includes a complex array of putative regulatory elements whose role in the viral expression is not completely understood. Here we demonstrate the presence of an NF-ÎșB-responsive element in the trans- activation response (TAR) region of HIV-1 that confers the full induction of HIV-1 long terminal repeat (LTR) in response to NF-ÎșB-activating stimuli, such as DNA alkylating agents, phorbol 12-myristate 13-acetate, and tumor necrosis factor-α. The TAR NF-ÎșB site GGGAGCTCTC spans from positions +31 to +40 and cooperates with the NF-ÎșB enhancer upstream of the TATA box in the NF-ÎșB-mediated induction of HIV-1 LTR. The conclusion stems from the following observations: (i) deletion of the two NF-ÎșB sites upstream of the TATA box reduces, but does not abolish, the HIV-1 LTR activation by NF-ÎșB inducers; (ii) deletion or base pair substitutions of the TAR NF-ÎșB site significantly reduce the HIV-1 LTR activation by NF-ÎșB inducers; (iii) deletions of both the NF-ÎșB sites upstream of the TATA box and the TAR NF- ÎșB site abolish the activation of HIV-1 LTR in response to NF-ÎșB inducers. Moreover, the p50·p65 NF-ÎșB complex binds to the TAR NF-ÎșB sequence and trans-activates the TAR NF-ÎșB-directed expression. The identification of an additional NF-ÎșB site in the HIV-1 LTR points to the relevance of NF-ÎșB factors in the HIV-1 life cycle

    An entropy method for floodplain monitoring network design

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    In recent years an increasing number of flood-related fatalities has highlighted the necessity of improving flood risk management to reduce human and economic losses. In this framework, monitoring of flood-prone areas is a key factor for building a resilient environment. In this paper a method for designing a floodplain monitoring network is presented. A redundant network of cheap wireless sensors (GridStix) measuring water depth is considered over a reach of the River Dee (UK), with sensors placed both in the channel and in the floodplain. Through a Three Objective Optimization Problem (TOOP) the best layouts of sensors are evaluated, minimizing their redundancy, maximizing their joint information content and maximizing the accuracy of the observations. A simple raster-based inundation model (LISFLOOD-FP) is used to generate a synthetic GridStix data set of water stages. The Digital Elevation Model (DEM) that is used for hydraulic model building is the globally and freely available SRTM DEM

    Stigma and discrimination (Sad) at the time of the sars-cov-2 pandemic

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    Infectious disease control is a crucial public health issue. Although it is important to urgently perform public health measures in order to reduce the risk of spread, it could end up stigmatizing entire groups of people rather than offering control measures based on sound scientific principles. This “us” versus “them” dynamic is common in stigmatization, in general, and indicates a way in which disease stigma can be viewed as a proxy for other types of fears, especially xenophobia and general fear of outsiders. The pandemic risk associated with SARS-CoV-2 infection led us to consider, among other related issues, how stigma and discrimination remain serious barriers to care for people suspected of being infected, even more if they are assisting professions, such as health workers, employed in emergency response. The purpose of this review is to evaluate and promote the importance of psychological aspects of the stigma and social discrimination (SAD) in pandemic realities and, more specifically, nowadays, in the context of SARS-CoV-2/COVID-19. Just as it happened with HIV, HCV, tuberculosis, and Zika, stigma and discrimination undermine the social fabric compromising the ethics and principles of civilization to which each individual in entitled. Recognizing disease stigma history can give us insight into how, exactly, stigmatizing attitudes are formed, and how they are disbanded. Instead of simply blaming the ignorance of people espousing stigmatizing attitudes about certain diseases, we should try to understand precisely how these attitudes are formed so that we can intervene in their dissemination. We should also look at history to see what sorts of interventions against stigma may have worked in the past. Ongoing research into stigma should evaluate what has worked in the past, as above-mentioned, providing us with some clues as to what might work in the current pandemic emergency, to reduce devastating discrimination that keeps people from getting the care they need. We propose a systematic and historical review, in order to create a scientific and solid base for the following SAD analysis. The aim is to propose a coping strategy to face stigma and discrimination (SAD) related to SARS-CoV-2/COVID-19 pandemic outbreak, borrowing coping strategy tools and solutions from other common contagious diseases. Furthermore, our study observes how knowledge, education level, and socioeconomic status (SES) can influence perception of SARS-CoV-2/ COVID-19 risk in a digital world, based on previous research, best practices, and evidence-based research
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