032: Thirty months outcomes after PCI of unprotected left main coronary artery according to the SYNTAX score

AimsTo assess middle term outcomes according to SYNTAX score and rates of delayed surgical/bleeding events after unprotected left main (LM) coronary artery (ULMCA) PCI in an unselected patients population.MethodsConsecutive patients treated by PCI for ULMCA were included among a single center 3508 PCI database within 36 months. Syntax scores were calculated, post discharge extracardiac surgery or hemorrhage were recorded during follow-up as clinical outcomes (Death, TVR, MACCE=cardiovascular death+MI+stroke+TLR).Results102 (3.6%) patients underwent PCI of the LM, including 21 protected LM. Among the 81 patients with PCI of ULMCA, mean age was 65±13, 27% had urgent PCI for AMI or cardiogenic shock, 61% had DES.SYNTAX score was 28±14 in mean and ≤22 in 30 (37%), 23 to 32 in 22 (27%) and ≥33 in 29 (36%) patients.At 30±11 months follow up (98% of the patients), death occurred in 24 patients (30%), TVR in 16 (20%) and MACCE in 35 (43%). Clinical events according to the SYNTAX score are shown in figure. No cardiovascular death occurred in patients with syntax ≤22. MACCE rates were significantly lower when DES were used (24% vs. 64%, p<0.05) and in case of non-urgent PCI (36% vs. 71%, p<0.05).During follow-up, 20 (25%) and 12 (15%) patients underwent unplanned extracardiac surgery and/or hemorrhage, leading to antiplatelet withdrawal in 31% of the cases.ConclusionsIn unselected patients treated by PCI of ULMCA with Syntax score ≤22, outcomes were found to be excellent with no cardiovascular death observed at 30 months. DES and non-urgent PCI were associated with a better prognosis. One patient out of three underwent unplanned extracardiac surgery or hemorrhage during follow up.Figure: 30-months outcomes according to SYNTAX scor

Persistent orocutaneous and anal fistulae induced by nicorandil: a case report

<p>Abstract</p> <p>Introduction</p> <p>Although nicorandil is prescribed widely, awareness of its potential to cause serious complications to the gastrointestinal tract mucosa is limited. Whilst nicorandil-induced oral and anal ulceration is well documented in the literature, nicorandil-induced fistulation is not. This is the first report in the literature of a single patient demonstrating simultaneous orocutaneous and anal fistulae during nicorandil therapy. Two separate cases of orocutaneous and anal fistulae associated nicorandil usage have previously been documented in specialist journals.</p> <p>Case presentation</p> <p>A 71-year-old Caucasian man presented with a 3-year history of concurrent orocutaneous and anal fistulae. He had been exposed to 30 mg twice-daily nicorandil therapy for 4 years. Both fistulae responded poorly to intensive and prolonged conventional treatment but healed promptly on reduction and eventual withdrawal of nicorandil therapy.</p> <p>Conclusion</p> <p>Management of resistant cases of orocutaneous and anal fistulae in patients on high-dose nicorandil therapy may be impossible without reduction or even withdrawal of nicorandil.</p

Video Watercolorization using Bidirectional Texture Advection

Special Issue: SIGGRAPH 2007International audienceIn this paper, we present a method for creating watercolor-like animation, starting from video as input. The method involves two main steps: applying textures that simulate a watercolor appearance; and creating a simplified, abstracted version of the video to which the texturing operations are applied. Both of these steps are subject to highly visible temporal artifacts, so the primary technical contributions of the paper are extensions of previous methods for texturing and abstraction to provide temporal coherence when applied to video sequences. To maintain coherence for textures, we employ texture advection along lines of optical flow. We furthermore extend previous approaches by incorporating advection in both forward and reverse directions through the video, which allows for minimal texture distortion, particularly in areas of disocclusion that are otherwise highly problematic. To maintain coherence for abstraction, we employ mathematical morphology extended to the temporal domain, using filters whose temporal extents are locally controlled by the degree of distortions in the optical flow. Together, these techniques provide the first practical and robust approach for producing watercolor animations from video, which we demonstrate with a number of examples

REALISE: Reconstruction of Reality from Image Sequences

REALISE has for principal goals to extract from sequences of images, acquired with a moving camera, information necessary for determining the 3D (CAD-like) structure of a real-life scene together with information about the radiometric signatures of surfaces bounding the extracted 3D objects (e.g. reflectance behaviour). The retrieved information is then integrated in a Virtual Reality (VR) software environment. R&D work is been performed principally in the following areas of Computer Vision & Computer Graphics: structure from motion, recovery of geometries, recovery of photometric and texture information, highly realistic rendering on the basis of empirically-based reflectance models, design and development of improved rendering processes together with a new VR system. Beside this innovative R&D work another key aspect of REALISE is to have Computer Vision & Computer Graphics cooperate to produce realistic 3D data efficiently

Near-Field Remote Sensing of Surface Velocity and River Discharge Using Radars and the Probability Concept at 10 U.S. Geological Survey Streamgages

Near-field remote sensing of surface velocity and river discharge (discharge) were measured using coherent, continuous wave Doppler and pulsed radars. Traditional streamgaging requires sensors be deployed in the water column; however, near-field remote sensing has the potential to transform streamgaging operations through non-contact methods in the U.S. Geological Survey (USGS) and other agencies around the world. To differentiate from satellite or high-altitude platforms, near-field remote sensing is conducted from fixed platforms such as bridges and cable stays. Radar gages were collocated with 10 USGS streamgages in river reaches of varying hydrologic and hydraulic characteristics, where basin size ranged from 381 to 66,200 square kilometers. Radar-derived mean-channel (mean) velocity and discharge were computed using the probability concept and were compared to conventional instantaneous measurements and time series. To test the efficacy of near-field methods, radars were deployed for extended periods of time to capture a range of hydraulic conditions and environmental factors. During the operational phase, continuous time series of surface velocity, radar-derived discharge, and stage-discharge were recorded, computed, and transmitted contemporaneously and continuously in real time every 5 to 15 min. Minimum and maximum surface velocities ranged from 0.30 to 3.84 m per second (m/s); minimum and maximum radar-derived discharges ranged from 0.17 to 4890 cubic meters per second (m3/s); and minimum and maximum stage-discharge ranged from 0.12 to 4950 m3/s. Comparisons between radar and stage-discharge time series were evaluated using goodness-of-fit statistics, which provided a measure of the utility of the probability concept to compute discharge from a singular surface velocity and cross-sectional area relative to conventional methods. Mean velocity and discharge data indicate that velocity radars are highly correlated with conventional methods and are a viable near-field remote sensing technology that can be operationalized to deliver real-time surface velocity, mean velocity, and discharge