10 research outputs found
Synthetic studies towards furanocembrane diterpenes. A total synthesis of bis-deoxylophotoxin
- Publication venue
- Publication date
- 01/01/2005
- Field of study
No full textl
- Author
- Berndt A.
- Camps M.
- Castillo J. J.
- Certal V.
- Certal V.
- Courtney K. D.
- Frazzetto M.
- Gonzalez-Lopez de Turiso F.
- Jackson S. P.
- Jia S.
- Knight Z. A.
- Kong D. X.
- Li J.
- Lin H.
- Lin H.
- Matsuno T.
- Matsuno T.
- Meadows S. A.
- Nylander S.
- Rewcastle G. W.
- Samuels Y.
- Sanchez R. M.
- Shuttleworth S. J.
- Vanhaesebroeck B.
- Walker E. H.
- Wee S.
- Yaguchi S.
- Zhang X. X.
- Zheng Z. H.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textApoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma
- Author
- A Dalpiaz
- A Petrelli
- A Sami
- B Chelli
- B Cosimelli
- B Costa
- B Costa
- B England
- C Mas-Moruno
- CE Griguer
- DR Green
- EF Pettersen
- F Da Settimo
- F Gonzalez-Lopez de Turiso
- G Prasad
- G Primofiore
- GM Morris
- J Plescia
- K Michelsen
- L D'Silva
- LT Vassilev
- M Krajewski
- M Persico
- M Reers
- ME Welsch
- NM O'Boyle
- R Dawson
- R Huey
- R Morphy
- R Villalonga-Planells
- S Castellano
- S Chowdhary
- S Fulda
- S Kondo
- S Shangary
- S Taliani
- T Behm
- TL Hwang
- V Papadopoulos
- VA Fadok
- Y Itahana
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textDiscovery of a Small Molecule MDM2 Inhibitor (AMG 232) for Treating Cancer
- Author
- Allen J. G.
- Beck H. P.
- Carry J.-C.
- Chene P.
- Daqing Sun
- Ding K.
- Ding K.
- Ding Q.
- El-Deiry W. S.
- Gonzalez-Lopez de Turiso F.
- Haupt Y.
- Hollstein M.
- Kubbutat M. H. G.
- Kussie P. H.
- Lucas B. S.
- Momand J.
- Oliner J. D.
- Oliner J. D.
- Rew Y.
- Roth J.
- Shangary S.
- Soussi T.
- Sun D.
- Tao W.
- Tovar C.
- Vassilev L. T.
- Vassilev L. T.
- Vazquez A.
- Vogelstein B.
- Vu B.
- Wen Z.
- Yosup Rew
- Yu S.
- Zhang Z.
- Zhao Y.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textDesign, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction
- Author
- A El-Faham
- A Feki
- A Ganesan
- AD Borthwick
- BP Orner
- C Dalvit
- D Reed
- D Rognan
- D Sun
- DA Freedman
- DC Fry
- DG Myszka
- ER Burkhardt
- F Gonzalez-Lopez de Turiso
- F Jam
- F Mutulis
- F Toledo
- FP Gasparro
- G Papalia
- H Yin
- J Momand
- Jaeki Min
- JC Brown
- JD Park
- JH Lee
- JM Nigro
- JP Plante
- K Michelsen
- KH Vousden
- Kristina Luthman
- LF Fieser
- LG Milroy
- LT Vassilev
- Luigi Iconaru
- M Aeluri
- M Aeluri
- M Tullberg
- M Tullberg
- M Wade
- M. Brett Waddell
- M. Tullberg
- Maria Quant
- Mariell Pettersson
- Morten Grøtli
- N Bharatham
- PH Kussie
- R Nishizawa
- R. Kiplin Guy
- Richard W. Kriwacki
- S Shangary
- SM Biros
- T Stiewe
- V Azzarito
- Y Rew
- Y Zhao
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
No full textDesign of Chemically Stable, Potent, and Efficacious MDM2 Inhibitors That Exploit the Retro-Mannich Ring-Opening-Cyclization Reaction Mechanism in Spiro-oxindoles
- Author
- Angelo Aguilar
- Bond G. L.
- Carry J. C.
- Denzil Bernard
- Ding K.
- Ding K.
- Ding Q.
- Donna McEachern
- Freedman D. A.
- Garcia-Echeverria C.
- Gonzalez-Lopez de Turiso F.
- Hainaut P.
- Jeffrey R. Deschamps
- Jianfeng Lu
- Juven-Gershon T.
- Liu Liu
- Momand J.
- Momand J.
- Momand J.
- Oliner J. D.
- Popowicz G. M.
- Popowicz G. M.
- Shangary S.
- Shangary S.
- Shaomeng Wang
- Shu L. H.
- Shvarts A.
- Vassilev L. T.
- Vassilev L. T.
- Vousden K. H.
- Wang S.
- Wang S.
- Wang Z. X.
- Wei Sun
- Wu X.
- Yu S.
- Zhang R.
- Zhang Z.
- Zhao Y.
- Zhao Y.
- Zhao Y.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textDiscovery and in Vivo Evaluation of ( S
- Author
- Ali K.
- Andreas Reichelt
- Andrew S. Tasker
- Angulo I.
- Ben Fisher
- Berndt A.
- Boes M.
- Brian Lucas
- Cushing T. D.
- Danca D. M.
- Daniela P. Metz
- Dawei Zhang
- Deanna Mohn
- Di Paolo G.
- Douglas A. Whittington
- D’Angelo N. D.
- Eicholt B. J.
- Emsley P.
- Felix Gonzalez-Lopez de Turiso
- Fruman D. A.
- Fung-Leung W. P.
- Gang Yu
- Gonzalez-Lopez de Turiso F.
- Hawkins P. T.
- Herko A.
- Jason Duquette
- Jennifer Seganish
- John D. McCarter
- John Whoriskey
- Julio C. Medina
- Kirk R. Henne
- Knight Z.
- Kristin Andrews
- Lanasa M. C.
- Lawrence R. McGee
- Leeanne Zalameda
- Liping H. Pettus
- Liu L.
- Liu X.
- Lucas C. L.
- Mahaney P. E.
- Mario Cardozo
- Matthew Brown
- Meth-Cohn O.
- Michael G. Johnson
- Michel P.
- Murshudov G. N.
- Otwinowski Z.
- Palanki M.
- Parker P. J.
- Pei Z.
- Randall Hungate
- Rashidi M.-R.
- Robert C. Wahl
- Robert M. Rzasa
- Roberts J. A.
- Ron C. Kelly
- Schaeffer E. M.
- Sharon Wannberg
- Sinclair A.
- Smith D. A.
- Soond R.
- Timothy D. Cushing
- Tisha San Miguel
- To Y.
- Vallerskog T.
- Vatee Pattaropong
- Vlahos C. J.
- Walker E. H.
- Wilcken R.
- Xiao He
- Xiaolin Hao
- Yasuo T.
- Yi Chen
- Yi-Ling Hu
- Youngsook Shin
- Zvelebil M. J.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full text8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction
- Author
- A Dierckx
- A Ganesan
- AL Jochim
- B Vogelstein
- BP Orner
- C Dalvit
- C Dyrager
- D Bliman
- D Sun
- DA Horton
- David Bliman
- DO Cicero
- DS Pedersen
- E Danelius
- F Gonzalez-Lopez de Turiso
- H Rosemeyer
- H Yin
- Jaeki Min
- Jesper R. Nilsson
- JH Lee
- Jimmy Jacobsson
- JJ Koivisto
- Joakim Andréasson
- JR Johansson
- K Michelsen
- KH Vousden
- L Zhang
- L Čechová
- LT Vassilev
- Luigi Iconaru
- M Aeluri
- M Fridén-Saxin
- M Meldal
- Mariell Pettersson
- Morten Grøtli
- MR Davis
- N Bharatham
- O Keskin
- PH Kussie
- R. Kiplin Guy
- Richard W. Kriwacki
- S Fletcher
- S Fletcher
- S Jones
- SW Kwok
- V Azzarito
- WE Stites
- WS Horne
- Y Rew
- Y Zhao
- Y-T Chang
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
No full textNovel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres
- Author
- Ada Chen
- Alexander M. Long
- Allen J. G.
- Ana Z. Gonzalez
- Anne Y. Saiki
- Arkin M. R.
- Ballatore C.
- Beck H. P.
- Bernard D.
- Brian M. Fox
- Carry J.-C.
- Chene P.
- Daqing Sun
- David Chow
- Ding K.
- Ding K.
- Ding Q.
- Dongyin Yu
- Furet P.
- Garcia-Echevarria C.
- Gonzalez-Lopez de Turiso F.
- Grasberger B. L.
- Hainaut P.
- Hardcastle J. R.
- Hazuda D. J.
- Hilary P. Beck
- Huang Y.
- Jason Duquette
- Jiasheng Fu
- Jing Zhou
- Joel McIntosh
- John Eksterowicz
- Jonathan D. Oliner
- Jonathan Houze
- Ju L.
- Jude Canon
- Julio C. Medina
- Kamal A.
- Kussie P. H.
- Lane D. P.
- Lawrence R. McGee
- Levine A. J.
- Lixia Jin
- Lucas B. S.
- Meanwell N. A.
- Mei-Chu Lo
- Oliner J. D.
- Parks D. J.
- Parks D. J.
- Paul Shaffer
- Peter Yakowec
- Qiuping Ye
- Rew Y.
- Riedinger C.
- Sarah Wortman
- Shishkin O V.
- Steven H. Olson
- Sun D.
- Tao Osgood
- Toledo F.
- Tovar C.
- Vassilev L. T.
- Vogelstein B.
- Vu B.
- Vu B. T.
- Wells J. A.
- Xiaoning Zhao
- Xin Huang
- Xuelei Yan
- Yihong Li
- Yosup Rew
- Yu S.
- Yun Ling
- Zhang Z.
- Zhao Y.
- Zhao Y.
- Zhihong Li
- Zhuang C.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textDrugging the p53 pathway: understanding the route to clinical efficacy
- Author
- A Bertamino
- A Bottger
- A Czarna
- A Efeyan
- A Gembarska
- A Hock
- A Lujambio
- A Petitjean
- A Ventura
- A Villunger
- AA Sablina
- AC Joerger
- AC Joerger
- AH Stegh
- AR Sawkar
- AR Sawkar
- AS Azmi
- AW Roberts
- B Graves
- B Vogelstein
- B Vogelstein
- B Vu
- BD Lehmann
- BL Grasberger
- BP Orner
- BS Lucas
- BZ Carter
- C Cao
- C Deng
- C Floquet
- C Li
- C Li
- C Riedinger
- C Tovar
- C Tovar
- C Tovar
- CA Brady
- CD Wassman
- CE Schafmeister
- CF Cheok
- CF Cheok
- CF Cheok
- Chandra S. Verma
- CJ Brown
- CJ Brown
- CJ Brown
- CJ Ross
- CM Rudin
- CP Martins
- D Bergamaschi
- D Carvajal
- D Garcia
- D Jiang
- D Kranz
- D Martinez Molina
- D Reed
- D Yecies
- David P. Lane
- DB Veprintsev
- DE MacCallum
- DE MacCallum
- DP Lane
- DP Lane
- DP Lane
- DS Auld
- DS Auld
- E Kerem
- E McCormack
- EA Komarova
- EM Michalak
- F Bernal
- F Bernal
- F Essmann
- F Gonzalez-Lopez de Turiso
- FM Boeckler
- G D'Orazi
- G Zauli
- G Zauli
- GL Bond
- H Yin
- HK Koblish
- HO Ohnstad
- HS Gannon
- I Garcia-Cao
- I Ray-Coquard
- I Ringshausen
- I Sermet-Gaudelus
- IM van Leeuwen
- IM van Leeuwen
- IM van Leeuwen
- IR Hardcastle
- J Kitagaki
- J Long
- J Momand
- J Phan
- J Ribas
- J Scotcher
- J Shen
- JE Chipuk
- JG Allen
- JG Jackson
- JL Blank
- JL Kaar
- JM Held
- JM Lambert
- JM Valentine
- JP Kruse
- JS Shin
- JT Patton
- K Kojima
- K Kojima
- K Kojima
- K Kojima
- K Michelsen
- K Oda
- K Sakaguchi
- K Schlereth
- K Schlereth
- K Shchors
- KD Robertson
- KD Sullivan
- KH Khoo
- Kian Hoe Khoo
- KM ElSawy
- L Chen
- L Coll-Mulet
- L Happo
- L Hernychova
- L Huang
- L Jiang
- L Li
- L Linde
- L Soucek
- LD Walensky
- LD Walensky
- LJ Valente
- LT Vassilev
- LT Vassilev
- M Gutekunst
- M Gutekunst
- M Konopleva
- M Konopleva
- M Konopleva
- M Kracikova
- M Leão
- M Li
- M Liu
- M Lu
- M Michaelis
- M Michaelis
- M Mihara
- M Pazgier
- M Wade
- M Wade
- M Wade
- MA Christophorou
- MF van Delft
- MH Aziz
- MJ Rigatti
- ML Choong
- ML Go
- MN Saha
- MS Davids
- MV Blagosklonny
- MV Blagosklonny
- N Basse
- N Issaeva
- N Rokaeus
- N Zache
- O Timofeev
- P Chene
- P Roxburgh
- P Secchiero
- P Secchiero
- P Secchiero
- P Smart
- PH Kussie
- PS Galatin
- PV Nikolova
- Q Ding
- QJ Lew
- R Kayali
- R Mir
- R Paris
- R Puca
- R Puca
- R Shalom-Feuerstein
- R Stoll
- R Vatsyayan
- R Verma
- R Wilcken
- R Zandi
- RE Henry
- RJ Jones
- RK Brachmann
- RW Rooswinkel
- S Lain
- S Lehmann
- S Shangary
- S Supiot
- S Sur
- S Wang
- SG Dastidar
- SJ Wei
- SJ Wei
- SM Mendrysa
- SM Mendrysa
- SM Picksley
- SM Rowe
- SN Loh
- SP Glaser
- T Li
- T Ma
- T Ni Chonghaile
- T Noguchi
- T Okamoto
- T Thompson
- T Van Maerken
- TG Hofmann
- TR Brummelkamp
- TT Vo
- VJ Bykov
- W Xue
- W Zhang
- W Zhou
- X Chen
- X Liu
- X Yu
- X Zhang
- Y Cho
- Y Ji
- Y Nakamura
- Y Rew
- Y Samuels-Lev
- Y Tabe
- Y Zhao
- YS Chang
- ZZ Brown
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full text
