A refugee-centred perspective

Part of Barbara Harrell-Bond’s legacy is the example she set of a refugee-centred approach to forced migration and refugee studies

From genomes to diaries: a 3-year prospective, real-life study of ragweed-specific sublingual immunotherapy

During the last decades, the prevalence of allergy has dramatically increased. Allergen-specific immunotherapy is the only currently available medical intervention that has the potential to affect the natural course of the disease, but there are still many questions and unmet needs hindering its widespread use to fulfill its treatment potential and maximize its benefits for the society. To provide a comprehensive phenome-wide overview in sublingual immunotherapy, using ragweed allergy as a target, we planned and carried out a longitudinal, prospective, observational, open-label study (DesensIT). In this paper we present challenges of using deep and comprehensive phenotypes embracing biological, clinical and patient-reported outcomes in allergen-specific immunotherapy and show how we designed the DesensIT project to optimize data collection, processing and evaluation

The Green Infrastructure Transect: An Organizational Framework for Mainstreaming Adaptation Planning Policies

When considering the range of spatial planning actions that cities can take to adapt to climate change, many of them fall under the conceptual umbrella of green infrastructure (GI). GI has been defined as the spatial planning of landscape systems at multiple scales and within varying contexts to provide open space, safeguard natural systems, protect agricultural lands, and ensure ecological integrity for cultural, social, and ecosystem benefits (Benedict andMcMahon, Renew Resour J 20:12–17, 2002, Green infrastructure: linking landscape and communities. Island Press,Washington, DC, 2006; Ahern, Cities of the future. IWA Publishing, London, 2008). While the traditional definition of GI refers to areas of land that are least intervened by human action, in this expanded definition, we are deliberately including areas that are engineered to mimic natural processes and which provide cost-effective ecosystem services. Although climate adaptation is a fairly new policy goal for GI (Gill et al., Built Environ 33(1):115–133, 2007; CCAP, http://www.ccap.org/docs/resources/989/Green Infrastructure FINAL.pdf, 2011), three key characteristics qualify GI as a suitable tool for adaptation planning including multifunctionality (to match ecosystem benefits with adaptation needs), multi-scalar nature of the spatial elements, and a ‘no-regrets approach’. However, GI needs to be matched to the character of the urban environment and coordinated across jurisdictions and planning scales to become an effective adaptation policy. In this chapter, we present a policy framework, the green infrastructure transect, that can help planners and policymakers identify appropriate GI policies for different urban environments and describe how these policies can create a regional adaptation planning framework