34 research outputs found

    Shear Localization in Dynamic Deformation: Microstructural Evolution

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    Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization

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    Sequence-tagged sites (STSs) were developed for the human alpha-tropomyosin gene TPM4. One STS was used to amplify DNA from somatic cell hybrids to localize TPM4 to chromosome 19. The other, a product from a long-range PCR, was used directly as a probe to refine the localization of TPM4 to 19p13.1 by fluorescence in situ hybridization to metaphase chromosome spreads

    Assignment of the human slow skeletal muscle troponin gene (TNNI1) to 1q32 by fluorescence in situ hybridisation

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    The human gene for slow-twitch skeletal muscle troponin I (TNNI1) has previously been mapped to 1q12-->qter using somatic cell hybrids. The TNNI1 locus has now been further localised to 1q32 using fluorescence in situ hybridization. This result confirms the previous assignment of this locus and maps the gene to a single chromosome band

    Assignment of the human skeletal muscle alpha actin gene (ACTA1) to 1q42 by fluorescence in situ hybridisation

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    The human skeletal muscle alpha actin gene (ACTA1) has previously been localized to 1p21-->qter using somatic cell hybrids and a specific probe from the 3' untranslated region of the gene. Using fluorescence in situ hybridization the localization has been confirmed and the ACTA1 gene precisely mapped to 1q42
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