Where Do You Start With Utilising Your Team?

Invited to deliver a lecture at the British Small Animal Veterinary Association annual international 4-day conference at the ICC Birmingham April 2nd-5th 2020 (postponed due to Covid-19). Lecture content aimed at informing and opening a dialogue with current veterinary undergraduates and recent graduates involving working in the team environment of the veterinary profession: 1. Better appreciate the roles of key stakeholders within the ‘team’. 2. Identify opportunities for reciprocal support starting out in practice. 3. Explore the value that they bring to the team as a student progressing to new graduate. Overall, fostering support for our veterinary undergraduate students and recent graduates across the world

Where Do You Start With Preventative Healthcare?

Invited to deliver a lecture at the British Small Animal Veterinary Association annual international 4-day conference at the ICC Birmingham April 2nd-5th 2020 (postponed due to Covid-19). Lecture content aimed at informing and opening a dialogue with current veterinary undergraduates and recent graduates covering common day-one topics in a pragmatic fashion: 1. Advise clients regarding appropriate vaccination regimes for cats, dogs and rabbits, in the UK. 2. Develop tailored preventative plans with clients, for cats, dogs and rabbits, in relation to worms, fleas, ticks and mites. 3. Assist clients in making informed decisions when it comes to neutering their cats, dogs and rabbits. Bringing together up-to-date thinking on these topics, from the point of view of the GP practitioner

Tangible outcomes of Internet use: from digital skills to tangible outcomes project report

In the past decade, digital divide discussions have moved from discussions of use or non-use, to a more nuanced recognition of different types and levels of access, motivation, skills and Internet use in a discourse that centres around digital inclusion and inequality. However, there remain challenges in measurement and conceptualisation. In 2014, the authors of this report started a project with the main objective to develop theoretically informed measures that can be used to explain how people use the Internet and what the benefits might be. A first report (van Deursen, Helsper & Eynon, 2014) looked at how to measure digital skills, an area in which a good amount of research has been done, although good measures with a solid theoretical grounding are scarce. In the current report, the authors move towards a research area that is very underdeveloped: the tangible outcomes that Internet use might result in. Most research in this area focuses on measuring engagement or different uses of the Internet and then assumes that activities performed online result in the corresponding outcomes. An unequal distribution of these types of engagement in turn is assumed to reinforce existing levels of social inequality. In this report, the framework used to design measures of engagement and related outcomes starts from the premise that outcomes of Internet use can be mapped onto different types of offline resources. It argues that a clear separation needs to be made between undertaking different kinds of activities in the digital sphere (i.e. digital resource fields) and the tangible outcomes in different spheres of everyday life (i.e. offline resource fields) that result from this engagement. &nbsp

Farnham rolls investigation

The object of this experiment was to investigate the possibility of obtaining pre-setting data for the 1 Farnham Rolls'. The experiment was carried out by applying certain deflections and measuring the resulting radii of curvature. Thus curves of curvature against deflection were produced for different sheet widths, and from these curves attempts to produce a conical frustum with prescribed radii were made. The results obtained can not be applied to conical parts, but this test served to indicate that it is possible to obtain pre-setting data for various applications

Elite athletes' genetic predisposition for altered risk of complex metabolic traits

BACKGROUND: Genetic variants may predispose humans to elevated risk of common metabolic morbidities such as obesity and Type 2 Diabetes (T2D). Some of these variants have also been shown to influence elite athletic performance and the response to exercise training. We compared the genotype distribution of five genetic Single Nucleotide Polymorphisms (SNPs) known to be associated with obesity and obesity co-morbidities (IGF2BP2 rs4402960, LPL rs320, LPL rs328, KCJN rs5219, and MTHFR rs1801133) between athletes (all male, n = 461; endurance athletes n = 254, sprint/power athletes n = 207), and controls (all male, n = 544) in Polish and Russian samples. We also examined the association between these SNPs and the athletes’ competition level (‘elite’ and ‘national’ level). Genotypes were analysed by Single-Base Extension and Real-Time PCR. Multinomial logistic regression analyses were conducted to assess the association between genotypes and athletic status/competition level. RESULTS: IGF2BP2 rs4402960 and LPL rs320 were significantly associated with athletic status; sprint/power athletes were twice more likely to have the IGF2BP2 rs4402960 risk (T) allele compared to endurance athletes (OR = 2.11, 95% CI = 1.03-4.30, P <0.041), and non-athletic controls were significantly less likely to have the T allele compared to sprint/power athletes (OR = 0.62, 95% CI =0.43-0.89, P <0.0009). The control group was significantly more likely to have the LPL rs320 risk (G) allele compared to endurance athletes (OR = 1.26, 95% CI = 1.05-1.52, P <0.013). Hence, endurance athletes were the “protected” group being significantly (p < 0.05) less likely to have the risk allele compared to sprint/power athletes (IGF2BP2 rs4402960) and significantly (p < 0.05) less likely to have the risk allele compared to controls (LPL rs320). The other 3 SNPs did not show significant differences between the study groups. CONCLUSIONS: Male endurance athletes are less likely to have the metabolic risk alleles of IGF2BP2 rs4402960 and LPL rs320, compared to sprint/power athletes and controls, respectively. These results suggest that some SNPs across the human genome have a dual effect and may predispose endurance athletes to reduced risk of developing metabolic morbidities, whereas sprint/power athletes might be predisposed to elevated risk

EPAS1 gene variants are associated with sprint/power athletic performance in two cohorts of European athletes

BACKGROUND: The endothelial PAS domain protein 1 (EPAS1) activates genes that are involved in erythropoiesis and angiogenesis, thus favoring a better delivery of oxygen to the tissues and is a plausible candidate to influence athletic performance. Using innovative statistical methods we compared genotype distributions and interactions of EPAS1 SNPs rs1867785, rs11689011, rs895436, rs4035887 and rs1867782 between sprint/power athletes (n = 338), endurance athletes (n = 254), and controls (603) in Polish and Russian samples. We also examined the association between these SNPs and the athletes’ competition level (‘elite’ and ‘sub-elite’ level). Genotyping was performed by either Real-Time PCR or by Single-Base Extension (SBE) method. RESULTS: In the pooled cohort of Polish and Russian athletes, 1) rs1867785 was associated with sprint/power athletic status; the AA genotype in rs1867785 was underrepresented in the sprint/power athletes, 2) rs11689011 was also associated with sprint/power athletic status; the TT genotype in rs11689011 was underrepresented sprint/power athletes, and 3) the interaction between rs1867785, rs11689011, and rs4035887 was associated with sprint/power athletic performance; the combinations of the AA genotype in rs4035887 with either the AG or GG genotypes in rs1867785, or with the CT or CC genotypes in rs11689011, were underrepresented in two cohorts of sprint/power athletes. CONCLUSIONS: Based on the unique statistical model rs1867785/rs11689011 are strong predictors of sprint/power athletic status, and the interaction between rs1867785, rs11689011, and rs4035887 might contribute to success in sprint/power athletic performance. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2164-15-382) contains supplementary material, which is available to authorized users

Dreaming of drams: Authenticity in Scottish whisky tourism as an expression of unresolved Habermasian rationalities

In this paper, the production of whisky tourism at both independently owned and corporately owned distilleries in Scotland is explored by focusing on four examples (Arran, Glengoyne, Glenturret and Bruichladdich). In particular, claims of authenticity and Scottishness of Scottish whiskies through commercial materials, case studies, website-forum discussions and 'independent' writing about such whisky are analysed. It is argued that the globalisation and commodification of whisky and whisky tourism, and the communicative backlash to these trends typified by the search for authenticity, is representative of a Habermasian struggle between two irreconcilable rationalities. This paper will demonstrate that the meaning and purpose of leisure can be understood through such explorations of the tension between the instrumentality of commodification and the freedom of individuals to locate their own leisure lives in the lifeworld that remains. © 2011 Taylor & Francis