Quasi-exospheric heat flux of solar-wind electrons

Density, bulk-velocity, and heat-flow moments are calculated for truncated Maxwellian distributions representing the cool and hot populations of solar-wind electrons, as realized at the base of a hypothetical exosphere. The electrostatic potential is thus calculated by requiring charge quasi-neutrality and the absence of electrical current. Plasma-kinetic coupling of the cool-electron and proton bulk velocities leads to an increase in the electrostatic potential and a decrease in the heat-flow moment

Charged-particle absorption by Io

An idealized two-dimensional model of the distorted electric field configuration, in the limit of a perfectly conducting satellite or satellite ionosphere, has been constructed. This model has been used to trace the adiabatic guiding-center trajectories of energetic protons and electrons across Jupiter's magnetic-field lines, which are taken as rectilinear. The adiabatic trajectories of very low-energy particles (cold-plasma) are thus found to avoid the satellite and escape absorption. In the limit of very high particle energies the adiabatic trajectories are undistorted, and absorption proceeds as if Io were an insulator. The particle absorbing characteristics of an electrically conducting Jovian satellite are found to depend on both the species and the energy of the incident particle, and the satellite's particle-absorbing cross section differs systematically from its geometric cross section

An emission mechanism for the Io-independent Jovian decameter radiation

A theory of the Io-independent decameter radiation is developed. The radiation results from excitation of the electromagnetic loss-cone instability by keV electrons, stably trapped near L = 6. The radiation is excited in Band 3 of the extraordinary mode. When the effects of refraction are estimated, it is shown that above 10 MHz radiation is beamed into the equatorial plane in a wide, but thin, conical sheet (Psi approximately equals 80 degrees). When the instability analysis is coupled with one of the octupole models of the Jovian magnetic field, the maximum convective growth of the instability occurs in the directions of the non-Io A, B, and C sources. The shape of the peak radio flux frequency spectrum is found to be a consequence of the loss cone shape of the electron distribution function

A beaming model of the Io-independent Jovian decameter radiation based on multipole models of the Jovian magnetic field

A geometrical model is presented in which the apparent source locations of the Io-independent decameter radiation are computed. The calculations assume that the radiation is produced by stably trapped electrons radiating near the electron gyrofrequency and that the emission is then beamed onto a conical surface. The maximum occurrence probability of noise storms is associated with regions in the Jovian magnetosphere where the axis of the emission cone is most inclined toward the Jovian equatorial plane. The calculations utilize and compare two of the octupole spherical harmonic expansions of the Jovian magnetic field constructed from data accumulated by the fluxgate and vector helium magnetometers on board Pioneer 11

Excitation of the Ganymede Ultraviolet Aurora

We analyze the ultraviolet aurorae observed on Ganymede by means of the Hubble Space Telescope and compare them to similar phenomena on Earth. We find that the tenuous nature of Ganymede's atmosphere precludes excitation of the aurora by high-energy electrons and requires a local acceleration mechanism. We propose the following as plausible mechanisms for generating both the continuous background emission and the intense auroral bright spots

Adaptive Response to DNA-Damaging Agents in Natural Saccharomyces cerevisiae Populations from “Evolution Canyon”, Mt. Carmel, Israel

BACKGROUND:Natural populations of most organisms, especially unicellular microorganisms, are constantly exposed to harsh environmental factors which affect their growth. UV radiation is one of the most important physical parameters which influences yeast growth in nature. Here we used 46 natural strains of Saccharomyces cerevisiae isolated from several natural populations at the "Evolution Canyon" microsite (Nahal Oren, Mt. Carmel, Israel). The opposing slopes of this canyon share the same geology, soil, and macroclimate, but they differ in microclimatic conditions. The interslope differences in solar radiation (200%-800% more on the "African" slope) caused the development of two distinct biomes. The south-facing slope is sunnier and has xeric, savannoid "African" environment while the north-facing slope is represented by temperate, "European" forested environment. Here we studied the phenotypic response of the S. cerevisiae strains to UVA and UVC radiations and to methyl methanesulfonate (MMS) in order to evaluate the interslope effect on the strains' ability to withstand DNA-damaging agents. METHODOLOGY/PRINCIPAL FINDINGS:We exposed our strains to the different DNA-damaging agents and measured survival by counting colony forming units. The strains from the "African" slope were more resilient to both UVA and MMS than the strains from the "European" slope. In contrast, we found that there was almost no difference between strains (with similar ploidy) from the opposite slopes, in their sensitivity to UVC radiation. These results suggest that the "African" strains are more adapted to higher solar radiation than the "European" strains. We also found that the tetraploids strains were more tolerant to all DNA-damaging agents than their neighboring diploid strains, which suggest that high ploidy level might be a mechanism of adaptation to high solar radiation. CONCLUSIONS/SIGNIFICANCE:Our results and the results of parallel studies with several other organisms, suggest that natural selection appears to select, at a microscale, for adaptive complexes that can tolerate the higher UV radiation on the "African" slope

Space Weathering on Near-Earth Objects investigated by neutral-particle detection

The ion-sputtering (IS) process is active in many planetary environments in the Solar System where plasma precipitates directly on the surface (for instance, Mercury, Moon, Europa). In particular, solar-wind sputtering is one of the most important agents for the surface erosion of a Near-Earth Object (NEO), acting together with other surface release processes, such as Photon Stimulated Desorption (PSD), Thermal Desorption (TD) and Micrometeoroid Impact Vaporization (MIV). The energy distribution of the IS-released neutrals peaks at a few eVs and extends up to hundreds of eVs. Since all other release processes produce particles of lower energies, the presence of neutral atoms in the energy range above 10 eV and below a few keVs (Sputtered High-Energy Atoms - SHEA) identifies the IS process. SHEA easily escape from the NEO, due to NEO's extremely weak gravity. Detection and analysis of SHEA will give important information on surface-loss processes as well as on surface elemental composition. The investigation of the active release processes, as a function of the external conditions and the NEO surface properties, is crucial for obtaining a clear view of the body's present loss rate as well as for getting clues on its evolution, which depends significantly on space weather. In this work, an attempt to analyze the processes that take place on the surface of these small airless bodies, as a result of their exposure to the space environment, has been realized. For this reason a new space weathering model (Space Weathering on NEO - SPAWN), is presented. Moreover, an instrument concept of a neutral-particle analyzer specifically designed for the measurement of neutral density and the detection of SHEA from a NEO is proposedComment: 36 page

Regulation, evolution and consequences of cotranslational protein complex assembly.

Most proteins assemble into complexes, which are involved in almost all cellular processes. Thus it is crucial for cell viability that mechanisms for correct assembly exist. The timing of assembly plays a key role in determining the fate of the protein: if the protein is allowed to diffuse into the crowded cellular milieu, it runs the risk of forming non-specific interactions, potentially leading to aggregation or other deleterious outcomes. It is therefore expected that strong regulatory mechanisms should exist to ensure efficient assembly. In this review we discuss the cotranslational assembly of protein complexes and discuss how it occurs, ways in which it is regulated, potential disadvantages of cotranslational interactions between proteins and the implications for the inheritance of dominant-negative genetic disorders

Unique Observations of a Geomagnetic SI^+ -- SI^- Pair: Solar Sources and Associated Solar Wind Fluctuations

The paper describes the occurrence of a pair of oppositely directed sudden impulses (SI), in the geomagnetic field ($\Delta$X), at ground stations, called SI${^{+}}$ -- SI${^{-}}$ pairs, that occurred between 1835 UT and 2300 UT on 23 April 1998. The SI${^{+}}$ -- SI${^{-}}$ pair, was closely correlated with corresponding variations in the solar wind density, while solar wind velocity and the southward component of the interplanetary magnetic field (Bz) did not show any correspondence. Further, this event had no source on the visible solar disk. However, a rear-side partial halo coronal mass ejection (CME) and an M1.4 class solar flare behind the west limb, took place on 20 April 1998, the date corresponding to the traceback location of the solar wind flows. This event presents empirical evidence, which to our knowledge, is the best convincing evidence for the association of specific solar events to the observations of an SI${^{+}}$ -- SI${^{-}}$ pair. In addition, it shows that it is possible for a rear side solar flare to propagate a shock towards the earth.Comment: The paper has just been accepted in the Journal of Geophysical Research (Space Physics) on 20 September 2010. It is 17 pages with 4 figure

Vascular endothelial growth factor (VEGF) fails to improve blood flow and to promote collateralization in a diabetic mouse ischemic hindlimb model

BACKGROUND: Angiogenic therapy with vascular endothelial growth factor (VEGF) has been proposed as a treatment paradigm for patients suffering from an insufficiency of collateral vessels. Diabetes is associated with increase in the production of VEGF and therefore additional VEGF may not be beneficial. Accordingly, we sought to determine the efficacy of VEGF therapy to augment collateral formation and tissue perfusion in a diabetic mouse ischemic hindlimb model. METHODS: Diabetic and non-diabetic mice were studied in parallel for the efficacy of VEGF administration. Diabetes was induced with streptozotocin. Hindlimb ischemia was produced by severing the left iliac artery. An outlet tube from an osmotic infusion pump with placebo/ 500 micrograms of plasmid-DNA encoding VEGF was fenestrated and tunneled into the left quadriceps muscle. RESULTS: VEGF induced more rapid and complete restoration of blood flow in normal mice. However, in the setting of diabetes there was no difference between VEGF Vs. placebo in the rate or adequacy of flow restoration. There was a significant increase in smooth muscle actin and Factor-VIII antigen densities in diabetic animals and in animals which received VEGF. CONCLUSIONS: Angiogenic therapy with VEGF in the setting of diabetes does not appear to have the beneficial effects seen in the absence of diabetes