PF-15 Surgical Management for Medial Patellar Luxation with Trochlear Block Recession and Lateral Imbrication Methods in Labrador Retriever Dog

Medial patellar luxation is a displacement of the patella from the trochlear sulcus[1]. Medial patellar luxation is one of the common cause of lameness in small-breed dogs, but it also occurs in large-breed dogs[1]. This case report will reveal how to diagnose and treat medial patellar luxatio

PF-14 Gastric Leiomyoma in a Twelve Year Old Pulli dog – A Case Report

Leiomyoma is a benign tumor arising from smooth muscle of hollow organs viz. uterus, vagina, intestines, stomach, urinary bladder and esophagus and is common in cow, dogs and fowl. Leiomyoma have slow-growing behaviour, localli invasive, malignant tumor of smooth muscle origin that typically is slow to metastasize4

PF-13 Fracture Fixation between Os Lumbalis II and III on a Three Month Old Kitten Using Parallel Technique

Spinal fractures, luxations, and fracture- luxations in dogs and cats are common and are often the result of vehicular injury. Other frequent causes of injury include animal attacks or falling from a height. Reports that describe the distribution of spinal column injuries indicate that they affect the lumbar vertebrae most frequently, followed by sacrococcygeal, thoracic, and cervical vertebrae2,3

Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated by Zinc Binding and Disulfide Bond Formation

SummaryPeriod (PER) proteins are essential components of the mammalian circadian clock. They form complexes with cryptochromes (CRY), which negatively regulate CLOCK/BMAL1-dependent transactivation of clock and clock-controlled genes. To define the roles of mammalian CRY/PER complexes in the circadian clock, we have determined the crystal structure of a complex comprising the photolyase homology region of mouse CRY1 (mCRY1) and a C-terminal mouse PER2 (mPER2) fragment. mPER2 winds around the helical mCRY1 domain covering the binding sites of FBXL3 and CLOCK/BMAL1, but not the FAD binding pocket. Our structure revealed an unexpected zinc ion in one interface, which stabilizes mCRY1-mPER2 interactions in vivo. We provide evidence that mCRY1/mPER2 complex formation is modulated by an interplay of zinc binding and mCRY1 disulfide bond formation, which may be influenced by the redox state of the cell. Our studies may allow for the development of circadian and metabolic modulators

Anisotropy parameters for two-color photoionization phases in randomly oriented molecules: theory and experiment in methane and deuteromethane

We present a combined theoretical and experimental work investigating the angle-resolved phases of the photoionization process driven by a two-color field consisting of an attosecond pulse train and an infrared pulse in an ensemble of randomly oriented molecules. We derive a general form for the two-color photoelectron (and time-delay) angular distribution valid also in the case of chiral molecules and when relative polarizations of the photons contributing to the attosecond photoelectron interferometer differ. We show a comparison between the experimental data and the theoretical predictions in an ensemble of methane and deuteromethane molecules, discussing the effect of nuclear dynamics on the photoionization phases. Finally, we demonstrate that the oscillating component and the phase of the two-color signal can be fitted using complex asymmetry parameters, in perfect analogy with the atomic case

Study of the therapeutic effects of an advanced hippotherapy simulator in children with cerebral palsy: a randomised controlled trial

<p>Abstract</p> <p>Background</p> <p>Although hippotherapy treatment has been demonstrated to have therapeutic effects on children with cerebral palsy, the samples used in research studies have been very small. In the case of hippotherapy simulators, there are no studies that either recommend or advise against their use in the treatment of children with cerebral palsy. The aim of this randomised clinical study is to analyse the therapeutic effects or the contraindications of the use of a commercial hippotherapy simulator on several important factors relating to children with cerebral palsy such as their motor development, balance control in the sitting posture, hip abduction range of motion and electromyographic activity of adductor musculature.</p> <p>Methods/Design</p> <p>The study is a randomised controlled trial. It will be carried out with a sample of 37 children with cerebral palsy divided into two treatment groups. Eligible participants will be randomly allocated to receive either (a) Treatment Group with hippotherapy simulator, maintaining sitting posture, with legs in abduction and rhythmic movement of the simulator or (b) Treatment Group maintaining sitting posture, with legs in abduction and without rhythmic movement of the simulator. Data collection and analysis: all measurements will be carried out by a specially trained blind assessor. To ensure standardization quality of the assessors, an inter-examiner agreement will be worked out at the start of the study. The trial is funded by the Department of Research, Innovation and Development of the Regional Government of Aragon (Official Bulletin of Aragon 23 July 2007), project number PM059/2007.</p> <p>Discussion</p> <p>Interest in this project is due to the following factors: Clinical originality (there are no previous studies analysing the effect of simulators on the population group of children with CP, nor any studies using as many variables as this project); Clinical impact (infantile cerebral palsy is a chronic multisystemic condition that affects not only the patient but also the patient's family and their close circle of friends); Practical benefits (the development of an effective treatment is very important for introducing this element into the rehabilitation of these children).</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN03663478.</p

An Improved 2-step Liquid Culture System for Efficient In Vitro Shoot Proliferation of Sundew (Drosera rotundifolia L.)

An efficient procedure for in vitro shoot production of the medicinal plant sundew (Drosera rotundifolia L.) was developed. Of three cytokinins tested, zeatin (ZEA) at a concentration of 2 μM resulted in the formation of large numbers of adventitious shoots on leaf explants. A larger size of the small shoots was achieved by combining a 2-weeks preculture with ZEA (step 1: shoot induction) with a 5-weeks main culture without plant growth regulators (step 2: shoot elongation). Liquid media were superior to semisolid media: An average of 27.4 shoots per leaf explant, and 53.3 shoots per shoot explant were achieved. The 2-step culture system with liquid media permits a comparatively cheap micropropagation of sundew as well as in vitro biomass production, with potential for scale-up

Development resources for Quality of Life in Old Age 2005

The central research question of this project is: Does Internet use represent a resource for life quality in old age? In order to answer this question, different areas of the life quality of older people on the one hand, and internet usage behaviour and attitudes towards the internet on the other are being investigated. Questions about the life quality of older people are linked to this research interest. Which areas of life are important for the life quality in old age? What role do different dimensions of life quality play? In order to answer these questions, an attempt is made to apply and further develop existing models of life quality. The use of the internet as a possible resource for life quality in old age requires a precise analysis. How is the internet used? Are there different types of use in which the influence on the life quality varies? The aim is a differentiated view of older internet users in connection with the life quality. Non-users were mainly included in the study as a comparison group. In addition, however, an attempt is made to identify and analyse reasons for non-use and the potential for future use in order to generate socio-political added value for the development of strategies to close the "digital divide" in addition to the gain in knowledge about internet users