313 research outputs found

    Female consumers' purchase intention of fair trade textile and clothing handicrafts: the roles of a geographical indication and fair trade knowledge in a brand equity model

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    The study investigated the effect of Geographical Indication (GI) certification and fair trade knowledge (FTK) on U.S. female consumers' perceived brand equity and purchase intention of fair trade (FT) textile and clothing handicrafts. Online experiments and a survey were conducted using the measurement items of perceived quality (PQ), brand awareness (BA), brand association (BS), uniqueness (UQ), willingness to pay a price premium (PP), purchase intention (PI), and FT knowledge level. The study results analysis indicated that consumers' willingness to a price premium for GI products and positive impact of FTK on the brand equity of FT handicrafts. In addition, the study findings also showed that increase in BS, UQ, and PP leads to the increase in PI. By exploring the relationship between GI, FTK, brand equity, and PI in FT textile and clothing handicrafts brands, this study contributed to the previously neglected literature and may help the sustainable management of FT textile and clothing handicrafts enterprises and organizations.Includes bibliographical references

    In situ endoscopic observation of higher-order mode conversion in a microwave mode converter based on an electro-optic probe system

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    Visualizing the electromagnetic field transformation inside a microwave mode conversion region has been considered to be only realizable by simulation studies. For the first time, we present a comprehensive experimental observation of the electric field transformation occurring inside a metallic waveguide TE01-to-TE02 mode converter. An efficient electro-optic (EO) probe and its associated probing system were used for measuring the electric field pattern in the external near-field region as well as in the internal and penetrated region of the mode converter. Utilizing the optically measured field patterns at the aperture of the mode converter, the conversion performance from the TE01 mode to the TE02 mode can be also evaluated. Experimentally measured field patterns near the apertures show excellent agreement with simulation data. The mode conversion to the next higher-order mode (TE01 to TE02) was experimentally demonstrated with phase-stabilized and field-animated post processing. The presented in situ endoscopic photonic measurement technique for the field evolution inside a semi-enclosed structure could be used for visually inspecting manufacturing errors in fabricated structures, and could be of great interest for research on higher-order mode formation and transmission.open0

    Dynamic Pricing in The Presence of Strategic Consumer with Product and Intertemporal Substitution

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    This study develops a dynamic pricing model with a quality substitutable product, taking into account strategic and myopic consumers. In each of the two periods, the firm can choose between offering a high quality product, a low quality product or both and the corresponding price for the product. Strategic consumers compare current utility with future utility in order to decide the time of purchase and the quality of the product in an attempt to maximize their utilities. Myopic consumers consider only current utility in purchasing of the products. We generate scenarios, prove whether a scenario is feasible and which scenario produces the best profit for the firm. Our result suggests that the firm obtains the best profit when it provides only high quality products in each of the two periods. In other words, the firm does not have to offer quality substitution as intertemporal substitution suffices to maximize the expected profit

    German Psychiatrists’ Observation and Interpretation of Religiosity/Spirituality

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    The purpose of this study was to explore how contemporary German psychiatrists think about religiosity/spirituality (ReS) in regard to their therapies. We conducted an anonymous survey among the clinical staff of psychiatry and psychotherapy departments in German university hospitals and faith-based clinics in the same cities. Two main instruments were used, the Duke University Religion Index (DUREL) and the questionnaire from Curlin et al. “Religion and Spirituality in Medicine: Physicians’ Perspectives.” A total of 123 psychiatrists participated in this survey. However, due to incomplete responses, only 99 questionnaires from psychiatrists were analyzed. Results show that German psychiatrists positively experience the influence of ReS on patients’ mental health. Psychiatrists’ own ReS significantly influenced their interpretation of the effect of ReS on psychiatric patients as well as their attitude toward ReS in the clinical setting. The more religious psychiatrists are, the more they tend to observe a positive influence of ReS on mental health. In light of these results, psychiatrists should be aware of their own religious/spiritual characteristics and also reconsider their assumptions about professional neutrality and value openness. Furthermore, training programs on religious/spiritual issues and effective teamwork with chaplains are recommended

    Numerical estimation on free electrons generated by shielded radioactive materials under various gaseous environments

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    We report simulation results on generation of free electrons due to the presence of radioactive materials under controlled pressure and gases using a general Monte Carlo transport code (MCNPX). A radioactive material decays to lower atomic number, simultaneously producing high energy gamma rays that can generate free electrons via various scattering mechanisms. This paper shows detailed simulation works for answering how many free electrons can be generated under the existence of shielded radioactive materials as a function of pressure and types of gases.open0

    Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K2P) and voltage-gated (Kv1.1 and Kv1.2) potassium channels

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    <p>Abstract</p> <p>Background</p> <p>Imiquimod (IQ) is known as an agonist of Toll-like receptor 7 (TLR7) and is widely used to treat various infectious skin diseases. However, it causes severe itching sensation as its side effect. The precise mechanism of how IQ causes itching sensation is unknown. A recent report suggested a molecular target of IQ as TLR7 expressed in dorsal root ganglion (DRG) neurons. However, we recently proposed a TLR7-independent mechanism, in which the activation of TLR7 is not required for the action of IQ in DRG neurons. To resolve this controversy regarding the involvement of TLR7 and to address the exact molecular identity of itching sensation by IQ, we investigated the possible molecular target of IQ in DRG neurons.</p> <p>Findings</p> <p>When IQ was applied to DRG neurons, we observed an increase in action potential (AP) duration and membrane resistance both in wild type and TLR7-deficient mice. Based on these results, we tested whether the treatment of IQ has an effect on the activity of K<sup>+ </sup>channels, K<sub>v</sub>1.1 and K<sub>v</sub>1.2 (voltage-gated K<sup>+ </sup>channels) and TREK1 and TRAAK (K<sub>2P </sub>channels). IQ effectively reduced the currents mediated by both K<sup>+ </sup>channels in a dose-dependent manner, acting as an antagonist at TREK1 and TRAAK and as a partial antagonist at K<sub>v</sub>1.1 and K<sub>v</sub>1.2.</p> <p>Conclusions</p> <p>Our results demonstrate that IQ blocks the voltage-gated K<sup>+ </sup>channels to increase AP duration and K<sub>2P </sub>channels to increase membrane resistance, which are critical for the membrane excitability of DRG neurons. Therefore, we propose that IQ enhances the excitability of DRG neurons by blocking multiple potassium channels and causing pruritus.</p

    Increase of Ceftazidime- and Fluoroquinolone-Resistant Klebsiella pneumoniae and Imipenem-Resistant Acinetobacter spp. in Korea: Analysis of KONSAR Study Data from 2005 and 2007

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    PURPOSE: Antimicrobial resistance monitoring could be a useful source of information for treating and controlling nosocomial infections. We analyzed antimicrobial resistance data generated by Korean Hospitals and by a commercial laboratory in 2005 and 2007. MATERIALS AND METHODS: Susceptibility data for 2005 and 2007 were collected from 37 and 41 hospitals, respectively, and from one commercial laboratory. Intermediate susceptibility was not included in the calculation of resistance rates. RESULTS: Methicillin-resistant Staphylococcus aureus (MRSA) (64%), third-generation cephalosporin-resistant Klebsiella pneumoniae (29%), fluoroquinolone-resistant Escherichia coli (27%), Pseudomonas aeruginosa (33%), and Acinetobacter spp. (48%), and amikacin-resistant P. aeruginosa (19%) and Acinetobacter spp. (37%) were prevalent in hospitals in 2007. A gradual increase of vancomycin-resistant Enterococcus faecium and imipenem-resistant Acinetobacter spp. was observed. Higher incidences of thirdgeneration cephalosporin-resistant E. coli and K. pneumoniae and imipenemresistant P. aeruginosa were found in the commercial laboratory than in the hospitals. CONCLUSION: Methicillin-resistant S. aureus, third-generation cephalosporin- resistant K. pneumoniae, and fluoroquinolone-resistant E. coli, P. aeruginosa and Acinetobacter spp. remain prevalent in Korea, while the incidence of vancomycin-resistant E. faecium and imipenem-resistant Acinetobacter spp. has increased gradually. The higher prevalences of third-generation cephalosporinresistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa in the commercial laboratory are a new concern.ope
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